王锐 - 重庆理工大学 - 药学与生物工程学院

个人简介

王锐，男，理学博士，副教授，中心实验室主任。学习经历： 2006/09-2009/06,中国科学院学，成都生物研究所，药物化学，博士 2003/09-2006/06，四川大学，化学学院，生物有机化学，硕士

研究领域

有机合成方法学研究：杂环合成研究、有机小分子催化不对称合成、C-C键形成研究；抗糖尿病药物及抗高血压药物合成及药物中间体合成研究。

近期论文

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[1]RuiWang,*Chun-hongAn,YangLi,YueZhao,TaoWang,AoLi*DirectSynthesisof2-ArylbenzothiazolesfromBenzothiazoleswithPhenylglycineDerivativesMediatedbyCu(OTf)2/K2S2O8TetrahedronLetters2015,56,2077-2082.(SCI2.6) [2]AoLi*,JunWang,Dan-PingZhu,Xiao-XunZhang,Ruo-LinPan,RuiWang*.Arctigeninsuppressestransforminggrowthfactor-β1-inducedexpressionofmonocytechemoattractantprotein-1andthesubsequentepithelial-mesenchymaltransitionthroughreactiveoxygenspecies-dependentERK/NF-κBsignalingpathwayinrenaltubularepithelialcells.Freeradicalresearch,2015,inpress,DOI:10.3109/10715762.2015.1038258.(SCI2.9) [3]RuiWang,*Yong-liangDing,HongLiu,ShuPeng,JieRen,LeiLiCopper-catalyzedmulticomponentreactionsof2-iodoanilines,benzylamines,andelementalsulfurtoward2-arylbenzothiazolesTetrahedronLetters2014,55,945-949.(SCI,2.6) [4]RuiWang,*HongLiu,LiangYue,Xiao-keZhang,Qiu-yuanTan,Ruo-linPanTransitionmetal-freedirectaminationofbenzoxazolesusingformamidesasnitrogensourcesTetrahedronLetters2014,55,2233-2237.(SCI,2.6,被引频次6) [5]RuiWang,*Wen-juanYang,LiangYue,WeiPan,Hong-yaoZeng.DDQ-PromotedC–SBondFormation:Synthesisof2-AminobenzothiazoleDerivativesunderTransition-Metal-,Ligand-,andBase-FreeConditions,Synlett.,2012,11,1643.(SCI,2.7,被引频次7，有机化学门户网站评述http://www.organic-chemistry.org;Eur.J.Org.Chem.综述) [6]RuiWang,*ZhiChen,LiangYue,WeiPan,Jun-JieZhao.Directtransitionmetal-freeC–Sbondformation:synthesisof2-aminobenzothiazolederivativesviabase-mediatedapproach.TetrahedronLett.,2012,53,4529.(SCI2.6,被引频次10). [7]JiYJ,ShuM,LinY,WangYQ,WangR,HuY,LinZH.Combined3D-QSARmodelingand moleculardockingstudyonazacyclesCCR5antagonists.JournalofMolecularStructure1045:35-41,2013.(SCI) [8]YangWJ,ShuM,WangYQ,WangR,HuY,Meng,LX,Lin,ZH.3D-QSARanddockingstudiesof3-PyridineheterocyclicderivativesaspotentPI3K/mTORinhibitors.JournalofMolecularStructure1054:107-116,2013.(SCI) [9]WangR,HuangTK,ShiL,.LiBG.LuXX.HeteropolyAcidsCatalyzedDirectMannichReactions:Three-ComponentSynthesisofN-Protectedβ-AminoKetones，Synlett.,2007,2197–2200.(SCI2.7,被引频次7) [10]WangR,LiBG,HuangTK,ShiL,LuXX.NbCl5-CatalyzedOne-potMannich-typeReaction:ThreeComponentSynthesisofβ–AminoCarbonylCompounds,TetrahedronLett.,2007,48,2071–2073.(SCI2.6,被引频次105) [11]WangR,LuXX,YuXQ,ShiL,SunY.Acid-CatalyzedSolvent-FreeSynthesisof2-ArylbenzimidazolesunderMicrowaveIrradiation.JournalofMolecularCatalysis.A,Chemical,2007,266,198–201.(SCI2.8,被引频次32)

学术兼职

ResearchonChemicalIntermediates评审专家，LettersinDrugDesign&Discovery评审专家，DrugDesign,DevelopmentandTherapy评审专家