个人简介
教师简介
沈燕,1989年生,四川大学药理学博士,讲师。作为主要研究人员参与完成了多项国家自然科学基金,在BritJPharmacol,BiochemBiophResCo,EurJMedChem,ScientificReports等期刊上发表多篇研究论文。
研究领域
主要从事靶向药物活性评价及机制研究和急性胰腺炎发病机制及药物干预。
近期论文
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代表性论文:
1.YShen,LiWen,RuiZhang,etal.DihydrodiosgeninprotectsagainstexperimentalacutepancreatitisandassociatedlunginjurythroughmitochondrialprotectionandPI3Kγ/Aktinhibition.BritJPharmacol.
2.YShen,WangChen,BaobingZhao,etal.CS1isaNovelTopoisomeraseIIαInhibitorwithfavorabledrugresistanceprofiles.BiochemBiophResCo
3.YShen,WChen,ZLiandYShen.SynthesisofAryl-SubstitutedNaphthalenoidsasPotentTopoisomeraseInhibitors.MedChem.
4.WangChen,YanShen,ZhenyuLietal.Designandsynthesisof2-phenylnaphthalenoidsasinhibitorsofDNAtopoisomeraseIIαandantitumoragents.EurJMedChem
5.RuiZhang,LiWen,YanShen,etal.OnecompoundofsaponinsfromDisocoreazingiberensisprotectedagainstexperimentalacutepancreatitisbypreventingmitochondria-mediatednecrosis.ScientificReports.
6.JQiu,BZhao,YShen,WChen,etal.Anovelp-terphenylderivativeinducingcell-cyclearrestandapoptosisinMDA-MB-435cellsthroughtopoisomeraseinhibition.EurJMedChem.