李仲 - 南京医科大学

个人简介

李仲，男，1975年生，博士。1998年本科毕业于南昌大学医学院，2007年博士毕业于香港科技大学生物系。2012年11月到南京医科大学工作，任教授，同时担任江苏省发育生物学学会理事。目前已在重要国际期刊中发表文章10篇（其中第一作者4篇，总影响因子>73）,代表性研究成果发表于JClinInvest、Diabetes、EMBOJ、CellMetabolism、JBC、PNAS、JLR等国际著名期刊。主持国家自然科学基金面上项目1项，做为学术骨干参与973项目两项。

研究领域

糖、脂代谢调控的分子机制研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

代表论著： 1.JohnZhongLi,YongchengHuang,RuchanKaraman,PavlinaT.Ivanova,H.AlexBrown,ThomasRoddy,JoseCastro-Perez,JonathanC.Cohen,andHelenH.Hobbs.ChronicoverexpressionofPNPLA3I148Minmouselivercauseshepaticsteatosis.JClinInvest122(11):4130-44（2012）(IF=13.073) 2.MaheshK.BasantaniMitchT.Sitnick,DaniBrenner,NoahP.Gardner,JohnZhongLi,GabrieleSchoiswohl,KuiYang,ManjuKumari,RichardWGross,RudolfZechner,andErinE.Kershaw.Pnpla3/Adiponutrindeficientinmicedoesnotcontributetofattyliverdiseaseorthemetabolicsyndrome.JLipidRes52(2):318–329(2011)(IF=5.559) 3.JohnZhongLi,YaoLei,YueWang,YinxinZhang,JingYe,XiayuXia,XianmingPanandPengLi.Controlofcholesterolbiosynthesis,uptakeandstorageinhepatocytesbyCideb.BiochimBiophysActa-MolecularandCellBiologyofLipids1801(5)：577-586(2010)(IF=5.269) 4.YongchengHuang,ShaoqingHe,JohnZhongLi,Young-KyoSeo,TimothyF.Osborne,JonathanC.Cohen,andHelenH.Hobbs.AFeed-forwardLoopAmplifiesNutritionalRegulationofPNPLA3.ProcNatlAcadSciUSA107,7892-7897(2010)(IF=9.681) 5.ShaoqingHe,ChristopherMcPhaul,JohnZhongLi,RitaGaruti,LisaKinch,NickVGrishin,JonathanC.Cohen,andHelenH.Hobbs.ASequenceVariation(I148M)inPNPLA3AssociatedwithNonalcoholicFattyLiverDiseaseDisruptsTriglycerideHydrolysis.JBiolChem285:6706-15(2010)(IF=4.773) 6.JingYe,JohnZhongLi,YangLiu,XuanheLi,TianshuYang,XiaodongMa,QingLi,ZeminYao,andPengLi.Cideb,anER-andlipiddroplet-Associatedprotein,mediatedVLDLlipidationandmaturationbyinteractingwithApolipoproteinB.CellMetab9(2),177-190(2009)(IF=13.668) 7.ShenYonToh,JingyiGong,GuoliDu,JohnZhongLi,ShuquanYang,JingYe,HuilanYao,YinxinZhang,BofuXue,QingLiHongyuanYang,ZilongWen,andPengLi.Up-regulationofmitochondrialactivityandacquirementofbrownadiposetissue-likepropertyinthewhiteadiposetissueoffsp27deficientmice.PLoSONE.3:e2890(2008)(IF=4.092) 8.JingzongQi,JingyiGong,TongjinZhao,JieZhao,PennyLam,JingYe,JohnZhongLi,JiaweiWu,Hai-mengZhou,andPengLi.DownregulationofAMP-activatedproteinkinasebyCidea-mediatedubiquitinationanddegradationinbrownadiposetissue.EMBOJ.271537-1548(2008)(IF=9.205) 9.JohnZhongLi,JingYe,BofuXue,JingzongQi,JingZhang,ZhihongZhou,QingLi,ZilongWenandPengLi.Cidebregulatesdiet-inducedobesity,liversteatosisandinsulinsensitivitybycontrollinglipogeneisandfattyacidoxidation.Diabetes56,2523-2532(2007)(IF=8.286)