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1.WangY,LinH,HaoN,ZhuZ,WangD,LiY,ChenH,ZhuY,HanX*.ForkheadboxO1mediatesdefectsinpalmitate-inducedinsulingranuleexocytosisbydownregulationofcalcium/calmodulin-dependentserineproteinkinaseexpressioninINS-1cells.Diabetologia.2015Mar22.[Epubaheadofprint]
2.QiaoN,XuC,ZhuYX,CaoY,LiuDC,HanX*.Ets-1asanearlyresponsegeneagainsthypoxia-inducedapoptosisinpancreaticβ-cells.CellDeathDis.2015Feb19;6:e1650.
3.NieJ,LiuX,LilleyBN,ZhangH,PanYA,KimballSR,ZhangJ,ZhangW,WangL,JeffersonLS,SanesJR,HanX*,ShiY*.SAD-Akinasecontrolsisletβ-cellsizeandfunctionasamediatorofmTORC1signaling.ProcNatlAcadSciUSA.2013Aug20;110(34):13857-62
4.ZhuY,YouW,WangH,LiY,QiaoN,ShiY,ZhangC,BleichD,HanX*.MicroRNA-24/MODYGeneRegulatoryPathwayMediatesPancreaticBeta-CellDysfunction.Diabetes.2013Sep;62(9):3194-206.
5.NieJ,LilleyBN,PanYA,FaruqueO,LiuX,ZhangW,SanesJR,HanX*,ShiY*.SAD-APotentiatesGlucose-StimulatedInsulinSecretionasaMediatorofGlucagon-LikePeptide1ResponseinPancreaticβCells.MolCellBiol.2013Jul;33(13):2527-34.
6.LinHY,YinY,ZhangJX,XuanH,ZhengY,ZhanSS,ZhuYX,HanX*,IdentificationofdirectforkheadboxO1targetsinvolvedinpalmitate-inducedapoptosisinclonalinsulin-secretingcellsusingchromatinimmunoprecipitationcoupledtoDNAselectionandligation,Diabetologia.2012Oct;55(10):2703-12..
7.NieJ,SunC,FaruqueO,YeG,LiJ,LiangQ,ChangZ,YangW,HanX*,ShiY*,Synapsesofamphidsdefective(SAD-A)kinasepromotesglucose-stimulatedinsulinsecretionthroughactivationofp21-activatedkinase(PAK1)inpancreaticβ-cells,JBiolChem.2012Jul27;287(31):26435-44.
8.MengZX,YinY,LvJH,ShaM,LinY,GaoL,ZhuYX,SunYJ,HanX*.AberrantactivationofliverXreceptorsimpairspancreaticbetacellfunctionthroughupregulationofSterolregulatoryelement-bindingprotein1cinmouseisletsandrodentcelllines.Diabetologia,2012Jun;55(6):1733-44.Epub2012Mar14.6.973
9.LiW,ChenZ,GongFR,ZongY,ChenK,LiDM,YinH,DuanWM,MiaoY,TaoM,HanX*,XuZK*.GrowthofthepancreaticcancercelllinePANC-1isinhibitedbyproteinphosphatase2Ainhibitorsthroughoveractivationofthec-JunN-terminalkinasepathway.EurJCancer.2011Nov;47(17):2654-64.Epub2011Sep28.4.944
10.ShuT,ZhuY,WangH,LinY,MaZ,HanX*.AGEsDecreaseInsulinSynthesisinPancreaticβ-CellbyRepressingPdx-1ProteinExpressionatthePost-TranslationalLevel.PLoSOne.2011Apr18;6(4):e18782.4.351
11.ChenF,ZhuY,TangX,SunY,JiaW,SunY,HanX*.DynamicRegulationofPDX-1andFoxO1ExpressionbyFoxA2inDexamethasone-InducedPancreatic{beta}-cellsDysfunction.Endocrinology.2011May;152(5):1779-88.Epub2011Mar8.4.752
12.LiW,ChenZ,ZongY,GongF,ZhuY,ZhuY,LvJ,ZhangJ,XieL,SunY,MiaoY,TaoM,HanX*,XuZ*.PP2AinhibitorsinduceapoptosisinpancreaticcancercelllinePANC-1throughpersistentphosphorylationofIKKαandsustainedactivationoftheNF-κBpathway.CancerLett.2011May28;304(2):117-27.Epub2011Mar3.3.741
13.ShenH,XuW,LuoW,ZhouL,YongW,ChenF,WuC,ChenQ,HanX*.Upregulationofmdr1geneisrelatedtoactivationoftheMAPK/ERKsignaltransductionpathwayandYB-1nucleartranslocationinB-celllymphoma.ExpHematol.2011May;39(5):558-69.Epub2011Feb24.3.106
14.ZhuY,ShuT,LinY,WangH,YangJ,ShiY,HanX*.Inhibitionofthereceptorforadvancedglycationendproducts(RAGE)protectspancreaticβ-cells.BiochemBiophysResCommun.2011Jan7;404(1):159-65.2.548
15.LinY,TangX,ZhuY,ShuT,HanX*.IdentificationofPARP-1asoneofthetranscriptionfactorsbindingtotherepressorelementinthepromoterregionofCOX-2.ArchBiochemBiophys.2011Jan1;505(1):123-9.3.046
16.GuoJ,ZhuJX,DengXH,HuXH,ZhaoJ,SunYJ,HanX*.Palmitate-inducedinhibitionofinsulingeneexpressioninratisletβ-cellsinvolvestheceramidetransportprotein.CellPhysiolBiochem.2010;26(4-5):717-28.3.563
17.LiW,XieL,ChenZ,ZhuY,SunY,MiaoY,XuZ*,HanX*.Cantharidin,apotentandselectivePP2Ainhibitor,inducesanoxidativestress-independentgrowthinhibitionofpancreaticcancercellsthroughG2/Mcell-cyclearrestandapoptosis.CancerSci.2010May;101(5):1226-33.3.771
18.GuoJ,QianY,XiX,HuX,ZhuJ,HanX*.Blockageofceramidemetabolismexacerbatespalmitateinhibitionofpro-insulingeneexpressioninpancreaticbeta-cells.MolCellBiochem.2010May;338(1-2):283-90.1.896
19.MengZ,LvJ,LuoY,LinY,ZhuY,NieJ,YangT,SunY,HanX*.ForkheadBoxO1/PancreaticandDuodenalHomeobox1intracellulartranslocationisregulatedbyc-JunN-terminalkinaseandinvolvedinprostaglandinE2-inducedpancreaticbeta-celldysfunction.Endocrinology.2009Dec;150(12):5284-93.4.945
20.ZhouX,ZhengM,ChenF,ZhuY,YongW,LinH,SunY,HanX*.Gefitinibinhibitstheproliferationofpancreaticcancercellsviacellcyclearrest.AnatRec(Hoboken).2009Aug;292(8):1122-7.1.569
21.ZhangXF,YongW,LvJH,ZhuYX,ZhangJJ,ChenF,ZhangRH,YangT,SunYJ,HanX*.InhibitionofforkheadboxO1protectspancreaticbeta-cellsagainstdexamethasone-induceddysfunction.Endocrinology.2009Sep;150(9):4065-73.4.945
22.XiaW,ZhaoT,LvJH,XuS,ShiJ,WangS,HanX*,SunYJ*.CelecoxibenhancedthesensitivityofcancercellstoanticancerdrugsbyinhibitionoftheexpressionofP-glycoproteinthroughaCOX-2-independentManner.JCellBiochem.2009Sep1;108(1):181-94.3.54
23.YinY,WangS,SunY,MattY,ColburnNH,ShuY*,HanX*.JNK/AP-1pathwayisinvolvedintumornecrosisfactor-alphainducedexpressionofvascularendothelialgrowthfactorinMCF7cells.BiomedPharmacother.2009Jul;63(6):429-35.2.198
24.MengZX,NieJ,LingJJ,SunJX,ZhuYX,GaoL,LvJH,ZhuDY,SunYJ,HanX*.ActivationofliverXreceptorsinhibitspancreaticisletbetacellproliferationthroughcellcyclearrest.Diabetologia.2009Jan;52(1):125-35.6.418
25.YangX,LinL,ZhangX,JiY,LvJ,ZhuY,YinY,SunY,HanX*.Identificationofanovelrepressorelementinthecyclo-oxygenase-2promoteranditsnuclearbindingprotein.ClinExpPharmacolPhysiol.2008Oct;35(10):1204-8.2.04
26.ZhuJ,YongW,WuX,YuY,LvJ,LiuC,MaoX,ZhuY,XuK,HanX*,LiuC*.Anti-inflammatoryeffectofresveratrolonTNF-alpha-inducedMCP-1expressioninadipocytes.BiochemBiophysResCommun.2008May2;369(2):471-7.2.75
27.MaC,ZhangJJ,DurrinKL.LvJH,ZhuD,HanX*,andSunY*.（2007).TheBCL2majorbreakpointregion(mbr)regulatesgeneexpression.Oncogene26（18）2649-57IF6.440co-correspondingauthor
28.MengZ,SunJ,LingJ,LvJ,ZhuDY,ChenQ,SunY*andHanX*.(2006)ProstaglandinE2regulatesFoxoactivityviatheAktpathway:implicationsforpancreaticislatbeta-celldysfunction.Diabetologia49(12):2959-68IF5.337correspondingauthor
29.ZhangJJ，MaCY,HanX*,DurrinL,andSunY*.(2006).TheBCL2majorbreakpointregion(mbr)possessestranscriptionalregulatoryfunction.Gene379：127-131.IF2.69*Co-correspondingauthor
30.SunY,WangT,YinY,XuS,MaC,HanX*(2006).ThebehaviorofSATB1,aMARbindingprotein,inresponsetoapoptosisstimulation.CellBiologyInternational.30(3):244-247.IF1.19correspondingauthor
31.WangZ,LvJH,ZhangRH,ZyX,SunY,ZhuJ,HanX*.(2006).Co-culturewithfatcellsinducesinsulinresistanceinprimaryhepatocytes.BBRC345(3):976-83.IF3.0*correspondingauthor
32.XuZK,ChenNG,MaCY,MengZX,SunYJ,HanX*.(2006).Roleofperoxisomeproliferator-activatedreceptorgammainglucose-inducedinsulinsecretion.ActaBiochim.Biophys.Sin.38(1):1-7.IF0.5correspondingauthor
33.LinJ,SunY,ZhuD,ChenQandHanX*.(2005).PotentialroleofNOinmodulationofCOX-2expressionandPGE2productioninpancreaticβ-cells.ActaBiochimicaetBiophysicaSinica37(2):139-146.IF0.5correspondingautho
34.HanX,ChenS,SunY,JerryL.Nadler,andBleichD.(2002).Inductionofcyclooxygenase-2(COX-2)geneinpancreaticbetacellsby12-lipoxygenasepathwayproduct12-hydroxyeicosatetraenoicacid(12-HETE).MolecularEndocrinology.19:2145-2154.
35.HanX,SunY,StephenScott,andDavidBleich.(2001).TissueInhibitorofMetalloproteinase-1(TIMP-1)preventscytokine-mediateddysfunctionandcytotoxicityinpancreaticisletsandb-cells.Diabetes.50(5):1047-55.
36.HanX,LundbergP,TanamachiB,OpenshawH,LongmateJ,CantinE.(2001)Genderinfluencesherpessimplexvirustype1infectioninnormalandgammainterferon-mutantmice.JVirol.Mar;75(6):3048-52.
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