个人简介
杨俭,女,1961年12月出生,博士。南京医科大学药理系副主任。江苏省“六大人才高峰”B类培养对象。从事药物代谢酶的转录(核受体)调节,药物、草药、激素之间的相互作用的研究。
。
目前主持课题:
国家自然科学基金“在对IL6的反应中DEC1负性调节肝脏药物代谢酶CYP3A4表达(30772616)(2008-2010)”
近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
近期发表论文:
JianYang,DeshiShi,DongfangYang,XiulongSong,andBingfangYan.Interleukin-6AlterstheCellularResponsivenesstoClopidogrel,Irinotecan,andOseltamivirbySuppressingtheExpressionofCarboxylesterasesHCE1andHCE2.MolPharmacol2007,72(3):684-694
YangJ,YanB.Photochemotherapeuticagent8-methoxypsoraleninducesCytochromeP4503A4andCarboxylesteraseHCE2:EvidenceonanInvolvementofthePregnaneXReceptor.ToxicolSci.2007;95(1):13-22
JianYang,JackChampitelli,GangHu,YanheLin,JinLuo,ChunXue.IncreaseinDPP-IVintheintestine,liverandkidneyoftherattreatedwithhighfatdietandstreptozotocin.LifeSci.2007,81:272-279.
YangJ,HuLF,LiuX,ZhouF,DingJH,HuG.Effectsofiptakalimontheextracellularglutamateanddopaminelevelsinthestriatumofunilateral6-hydroxydopamine-lesionedrats:amicrodialysisstudy.LifeSci.2006,78(17):1940-4.
LiY,XieM,YangJ,YangD,DengR,WanY,YanB.TheexpressionofantiapoptoticproteinsurvivinistranscriptionallyupregulatedbyDEC1primarilythroughmultiplesp1bindingsitesintheproximalpromoter.Oncogene.2006Jun1;25(23):3296-306.
ShiD,YangJ,YangD,LucluyseEL,BlackC,YouL,AkhlaghiF,YanB.Anti-Influenzaviralprodrugoseltamivirisactivatedbycarboxylesteraseandtheactivationisinhibitedby?anti-plateletagentclopidogrel.JPharmacolExpTher.2006;319(3):1477-84.