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个人简介

A.B., Cornell University, 1963 Ph.D., University of Rochester, 1967

研究领域

Organic Total Synthesis of Natural Products

近期论文

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Chauhan, P. S.; Sacher, J. R.; Weinreb, S. M. Synthesis of the Tetracyclic Skeleton of the Lycopodium Alkaloid Lycopladine H via a Pivotal Double Hydroformylation/Intramolecular Reductive Amination Sequence. Org. Lett. 2015, 17, 806. Nocket, A. J.; Feng, Y.; Weinreb, S. M. Construction of the Myrioneuron Alkaloids: A Total Synthesis of (±)-Myrioneurinol. J. Org. Chem. 2015, 80, 1116. Nocket, A. J.; Weinreb, S. M. Total Synthesis of the Tetracyclic Antimalarial Alkaloid (±)-Myrioneurinol. Angew. Chem. Int. Ed. 2014, 53, 14162 Chauhan, P. S.; Weinreb, S. M. Convergent Approach to the Tetracyclic Core of the Apparicine Class of Indole Alkaloids via a Key Intermolecular Nitrosoalkene Conjugate Addition. J. Org. Chem. 2014, 79, 6389. Feng, Y.; Majireck, M. M.; Weinreb, S. M. Total Syntheses of the Monoterpene Indole Alkaloids (±)-Alstilobanine A and E, and (±)-Angustilodine. J. Org. Chem. 2014, 79, 7 (Featured Article). Sengupta, R.; Weinreb, S. M. A One-Pot Umpolung Method for Preparation of a-Aryl Nitriles from a-Chloroaldoximes via Organocuprate Additions to Transient Nitrosoalkenes. Synthesis 2012, 44, 2933. Feng, Y.; Majireck, M. M.; Weinreb, S. M. Total Synthesis of the Unusual Monoterpenoid Indole Alkaloid (±)-Alstilobanine A. Angew. Chem. Int. Ed. 2012, 51, 12846. Sacher, J. R.; Weinreb, S. M. Construction of the Azocane (Azacyclooctane) Moiety of the Lycopodium Alkaloid Lycopladine H via an Intramolecular Hydroaminomethylation Strategy. Org. Lett. 2012, 14, 2172. Chauhan, P. S.; Majireck, M. M.; Weinreb, S. M. Regioselective a-Monochlorination of N-Protected-3 piperidones. Heterocycles 2012, 84, 577. Sacher, J. R.; Weinreb, S. M. Discussion Addendum for 2-Trimethylsilylethanesulfonyl Chloride (SES-Cl). Org. Synth. 2012, 89, 34. Sengupta, R.; Witek, J. A.; Weinreb, S. M. Stereochemical Investigations of Conjugate Additions of Carbon- and Heteronucleophiles to Ring-Substituted Nitrosocyclohexenes. Tetrahedron 2011, 67, 8229. Sacher, J. R.; Weinreb, S. M. Exploratory Studies Towards a Total Synthesis of the Unusual Bridged Tetracyclic Lycopodium Alkaloid Lycopladine H. Tetrahedron 2011, 67, 10203. Witek, J. A.; Weinreb, S. M. Investigation of the Stereochemistry of Intermolecular Conjugate Additions of Nucleophiles to Acyclic Nitrosoalkenes. Org. Lett. 2011, 13, 1258. Kumar, P.; Li, P.; Korboukh, I.; Wang, T. L.; Yennawar, H.; Weinreb, S. M. Further Studies of Intramolecular Michael Reactions of Nitrosoalkenes for Construction of Functionalized Bridged Ring Systems. J. Org. Chem. 2011, 76, 2094. Majireck, M. M.; Witek, J. A.; Weinreb, S. M. An Expedient Reductive Method for Conversion of Ketoximes to the Corresponding Carbonyl Compounds. Tetrahedron Lett. 2010, 51, 3555. Liu, P.; Seo, J. H.; Weinreb, S. M. Evolution of a Strategy for Total Synthesis of the Marine Fungal Alkaloid (±)-Communesin F. J. Org. Chem. 2010, 75, 2667. Li, P.; Majireck, M. M.; Witek, J. A.; Weinreb, S. M. Efficient Methodology for Alkylation of Vinylnitroso Compounds with Carbon Nucleophiles. Tetrahedron Lett. 2010, 51, 2032. Liu, P.; Seo, J. H.; Weinreb, S. M. A New Total Synthesis of the Polycyclic Fungal Metabolite (±)-Communesin F. Angew. Chem. Int. Ed. 2010, 49, 2000.

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