个人简介
2003年、2007年在四川大学生命科学学院获理学学士、硕士学位
2011年 国家纳米科学中心获物理化学博士学位。
2011年-至今,中国科学院高能物理研究所助理研究员、副研究员、特聘青年研究员
近年来,主要从事纳米材料的生物医学效应及机制的研究;并以同步辐射等放射分析手段为基础,逐步建立与发展纳米-生物界面的创新分析方法,实现界面结构的高分辨解析、实现单细胞与单颗粒高分辨成像、实现纳米化学反应的高灵敏分析,为纳米生物医学效应研究提供强有力的分析手段。研究成果发表在J. Am. Chem. Soc., Anal. Chem., Adv. Mater., Nano Lett., ACS Nano, Biomaterials等期刊,共发表50余篇论文, 被引用5000次。荣获中国毒理学会-联合利华毒理学替代法创新奖(2017)、中国毒理学会-英国皇家化学会优秀论文奖(2015)、国际纳米药剂学青年科学家(2012)等奖励。目前,与北京同步辐射装置、上海光源、合肥同步辐射、美国先进光源(APS)、布鲁克海文国家实验室(NSLSII)、加拿大光源(CLS)、美国FDA等知名研究机构的实验室建立了密切合作。
近期论文
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Zhang, G.; Cong, Y.; Liu, F.-L.; Sun, J.; Zhang, J.; Cao, G.; Zhou, L.; Yang, W.; Song, Q.; Wang, F.; Liu, K.; Qu, J.; Wang, J.; He, M.; Feng, S.; Baimanov, D.; Xu, W.; Luo, R.-H.; Long, X.-Y.; Liao, S.; Fan, Y.; Li, Y.-F.; Li, B.; Shao, X.; Wang, G.; Fang, L.; Wang, H.; Yu, X.-F.; Chang, Y.-Z.; Zhao, Y.; Li, L.; Yu, P.; Zheng, Y.-T.; Boraschi, D.; Li, H.; Chen, C.; Wang, L.; Li, Y., A nanomaterial targeting the spike protein captures SARS-CoV-2 variants and promotes viral elimination. Nature Nanotechnology 2022, 10.1038/s41565-022-01177-2.
Liming Wang, Liang Yan, Jing Liu, Chunying Chen*, Yuliang Zhao*. Quantification of Nanomaterial/Nanomedicine Trafficking in vivo. Anal. Chem. 2018, 90 (1), 589-614.
Jabran Saleem, Liming Wang*, Chunying Chen*. Carbon-Based Nanomaterials for Cancer Therapy via Targeting Tumor Microenvironment. Adv. Healthc. Mater. 2018, 1800525.
Xiumei Jiang#; Liming Wang#; Yinglu Ji; Jinglong Tang; Xin Tian; Mingjing Cao; Jingxuan Li; Shuying Bi; Xiaochun Wu*; Chunying Chen*; Junjie Yin. Interference of Steroidogenesis by Gold Nanorod Core/Silver Shell Nanostructures: Implications for Reproductive Toxicity of Silver Nanomaterials. Small 2017, 13 (10), 1602855.
Chengdu Sun#, Liming Wang#, Dan Gao, Yuanming Pan, Yuliang Zhao, Chunying Chen*, Mingzhou Guo*. C60(OH)22: A Potential Histone Deacetylase Inhibitor with Anti-angiogenic Activity. Nanoscale 2016, 8, 16332-16339.
Jing Liu, Pengyang Wang, Xiao Zhang, Liming Wang*, Dongliang Wang, Zhanjun Gu, Jinglong Tang, Mengyu Guo, Mingjing Cao, Huige Zhou, Ying Liu*, Chunying Chen*. Rapid Degradation and High Renal Clearance of Cu3BiS3 Nanodots for Efficient Cancer Diagnosis and Photothermal Therapy in vivo. ACS Nano, 2016, 10: 4587-4598.(被引60次)
Mingjing Cao, Pengyang Wang, Yu Kou, Jing Wang, Jing Liu, Yanhui Li, Jiayang Li, Liming Wang*, Chunying Chen*. Gadolinium (III)-Chelated Silica Nanospheres Integrating Chemo- and Photothermal Therapy for Cancer Treatment and Magnetic Resonance Imaging. ACS Appl. Mater. Interfaces 2015, 7(45): 25014-25023.
Liming Wang, Tianlu Zhang, Panyun Li, Wanxia Huang, Jinglong Tang, Pengyang Wang, Jing Liu, Qingxi Yuan, Ru Bai, Kai Zhang, Yuliang Zhao, Chunying Chen. Use of Synchrotron Radiation-Analytical Techniques to Reveal Chemical Origin of Silver-Nanoparticle Cytotoxicity. ACS Nano, 2015, 9: 6532-6547.(被引80次)
Liming Wang, Qiang Sun, Xin Wang, Tao Wen, Junjie Yin, Pengyang Wang, Ru Bai, Xiang-Qian Zhang, Lu-Hua Zhang, An-Hui Lu*, Chunying Chen*. Using Hollow Carbon Nanospheres as a Light-induced Free Radical Generator to Overcome Chemotherapy Resistance. J. Am. Chem. Soc. 2015, 137: 1947–1955.(被引80次)
Liming Wang, Xiaoying Lin, Jing Wang, Zhijian Hu, Yinglu Ji, Shuai Hou, Yuliang Zhao, Xiaochun Wu*, Chunying Chen*. Novel Insights into Combating Cancer Chemotherapy Resistance Using a Plasmonic Nanocarrier: Enhancing Drug Sensitiveness and Accumulation Simultaneously with Localized Mild Photothermal Stimulus of Femtosecond Pulsed Laser. Adv. Funct. Mater. 2014, 24: 4229-4239.
Liming Wang, Jingyuan Li, Jun Pan, Xiumei Jiang, Yinglu Ji, Yufeng Li, Ying Qu, Yuliang Zhao, Xiaochun Wu*, Chunying Chen*. Revealing the Binding Structure of the Protein Corona on Gold Nanorods Using Synchrotron Radiation-Based Techniques: Understanding the Reduced Damage in Cell Membranes. J. Am. Chem. Soc. 2013, 135: 17359?17368.(被引125次)
Zhenjiang Zhang#, Liming Wang #, Jing Wang#, Xiumei Jiang, Xiaohui Li, Zhijian Hu,Yinglu Ji, Xiaochun Wu*, Chunying Chen*,Mesoporous Silica-Coated Gold Nanorods as a Light-Mediated Multifunctional Theranostic Platform for Cancer Treatment. Adv. Mater. 2012, 24: 1418-1423.(被引670次)
Liming Wang, Ying Liu, Wei Li, Xiumei Jiang, Yinglu Ji, Xiaochun Wu, Ligeng Xu, Yang Qiu, Kai Zhao, Taotao Wei, Yufeng Li, Yuliang Zhao, Chunying Chen. Selective Targeting of Gold Nanorods at the Mitochondria of Cancer Cells: Implications for Cancer Therapy. Nano Lett. 2011, 11: 772-780. (被引370次)