李志广 - 大连医科大学 - 国际教育学院

个人简介

李志广职务: 教授专业: 生物化学与分子生物学 Education/Working Experience 201402—Present China Dalian Medical University Professor 201105—201402 USA Johns Hopkins University Postdoctoral Research Scientist / Teaching assistant 200806—201105 USA National Center for Toxicological Research Postdoctoral fellow 200207—200407 China CapitalBio Corporation Research Scientist 200107—200207 China YiShengTang Biology Medicine Ltd Research Scientist 200409 — 200807 China Institute of Biophysics, Chinese Academy of Sciences Biochemistry and Molecular Biology Ph.D. 199809 — 200107 China Fu Dan University Microbiology M.S. 199409 — 199807 China Wu Han University Microbiology B.S. Research Projects/Grants Liao Ning Pan Deng Scholar Fund(2014-2016) NSFC General Projects: Mechanism Investigation of the establishment of aberrant methylation at tumor suppressor gene promoters via DNMT1 and polII.(2014-2018) Admission Plan/Requirements The applicant should be between 23-35 years old, healthy, has obtained bachelor degree with good scores(GPA>3.75), has working experience, has solid financial support to afford the study and living expenses in China. Requires students to have good biological statistics or bioinformatics background. This major can accept one student.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Zhiguang Li, Hongzheng Dai, Suzanne N. Martos, Beisi Xu, Yang Gao, Teng Li, Guangjing Zhu, Dustin E. Schones, and Zhibin Wang. Distinct roles of DNMT1-dependent and -independent methylation patterns in the genome of mouse embryonic stem cells. Genome Biology. 2015 Jun 2;16:115.(IF=10.81) 2. Li Zhiguang, Qin T, Wang K, Hackenberg M, Yan J, Gao Y, Yu L, Shi L, Su Z, Chen T: Integrated microRNA, mRNA, and protein expression profiling reveals microRNA regulatory networks in rat kidney treated with a carcinogenic dose of Aristolochic Acid. BMC genomics 2015, 16(1):1-11 (IF=4.041) 3. Wang Y, Li Zhiguang, Chen T, Zhao X: Understanding the aristolochic acid toxicities in rat kidneys with regulatory networks. IET Systems Biology 2015, 9(4):141-146 Accepted. (IF=1.672) 4. Meng F, Li Zhiguang, Yan J, Manjanatha M, Shelton S, Yarborough S, Chen T: Tissue-specific microRNA responses in rats treated with mutagenic and carcinogenic doses of aristolochic acid. Mutagenesis 2014, 29(5):357-65. (IF=3.497) 5. Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Zhiguang, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B: The ubiquitin ligase stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor foxp3. Immunity 2013, 39(2):272-285. (IF=19.748) 6. Meng F, Hackenberg M, Li Zhiguang, Yan J, Chen T: Discovery of novel microRNAs in rat kidney using next generation sequencing and microarray validation. PloS one 2012, 7(3):e34394. (IF=3.73) 7. Chen T, Li Zhiguang, Yan J, Yang X, Salminen W: MicroRNA expression profiles distinguish the carcinogenic effects of riddelliine in rat liver. Mutagenesis 2012, 27(1):59-66. (IF=3.5)

学术兼职

Psychoneuroimmunology Research Society 2013.11— Present Environmental Mutagen Society 2011.01— Present Member Member The Society of Toxicology 2009.09—Present Member