研究领域
物理有机化学,生物有机化学与化学生物学
有机合成,生物偶联,超分子构建,药物及载体。
近期论文
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J. Guo, G.J. Chen, X.H. Ning, J.F. Zhou, X.R. Li, A. Jagielska, B.Q. Xu& G.-J. Boons.A Chemo-Mechanical Tweezer for Single Molecular Characterization of Soft Materials.Chem. Eur. J.2012,18,4568-4574.
J. Guo, G.J. Chen, X.H. Ning, M.A. Wolfert, X.R. Li, B.Q. Xu& G.-J. Boons.Surface Modification of Polymeric Micelles by Strain-Promoted Alkyne-AzideCycloaddition.Chem. Eur. J.2010, 16, 13360-13366.(Selected for a Frontipiece by Chem. Eur. J.; Highlighted by “Surface Functionalization by Strain-Promoted Alkyne–Azide Click Reactions” R. Manova, T.A. van Beek& H. Zuilhof, Angew. Chem. Int. Ed. 2011, 50, 5428-5430.)
J. Guo, P.C. Mayers, G. Breault& C.A. Hunter.Synthesis of a molecular trefoil knot by folding and closing on an octahedral coordination template.Nat. Chem.2010, 2, 218-222.(Highlighted by: “Chemical topology: Tying up some loose ends” E.E. Fenlon, Nat. Chem. 2010, 2, 156-157; “Chemistry: Tie the knot” Nature 2010, 463, 853; “Closure on the knotty problem” K. McAlpine, Chem. World 2010, 7(3), 28.)
X.H. Ning, J. Guo, M.A. Wolfert& G.-J.Boons. Visualizing Metabolically-Labeled Glycoconjugates of Living Cells by Copper-Free and Fast HuisgenCycloadditions. Angew. Chem. Int. Ed.2008, 47, 2253-2255.(Featured as Very Important Paper (VIP); Highlighted by Faculty of 1000 Biology P. Dawson, Jun. 04, 2008.)
J. Guo, J. Asong& G.-J.Boons.Selective Inhibition of Glycosidases by Feedback Prodrugs.Angew. Chem. Int. Ed.2006, 45, 5345-5348.