个人简介
王先龙,博士,福建医科大学生物信息学系教授。2006年于美国布林莫尔学院化学系获得哲学博士(PhD)学位。2008年至2017年在电子科技大学任教,2017年调入福建医科大学工作。主要研究领域为生物信息学和计算生物学,重点关注肿瘤标志物发现和药物基因组学研究,特别是中枢神经系统肿瘤的诊断和治疗。已在国际学术期刊上发表SCI检索论文40余篇(第一作者或通讯作者共二十余篇),出版英文学术专著一本,主持国家自然科学基金青年基金一项,主研国家自然科学基金重点项目一项,主持教育部博士点基金一项,主持成都市中小企业创新基金一项,主持研发了多款科学计算软件。在教学方面,承担多项校级教改项目,发表多篇教学论文,出版教材一部,获得多项校级和省级教学成果奖,作为教练带领本科生参加国际基因遗传工程机器大赛(iGEM),获得软件队金牌。
近期论文
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1.QingzhouGuan,HaidanYan,YanhuaChen,BaotongZheng,HaoCai,JunHe,KaiSong,YouGuo,LuAo,HuapingLiu,WenyuanZhao,XianlongWang*andZhengGu*.Quantitativeorqualitativetranscriptionaldiagnosticsignatures?Acasestudyforcolorectalcancer.BMCGenomics.2018,19:99(DOI:10.1186/s12864-018-4446-y)(JCR二区,IF3.729)
2.HaoCai,XiangyuLi,JingLi,QiruiLiang,WeichengZheng,QingzhouGuan,ZhengGuo*,XianlongWang*.Identifyingdifferentiallyexpressedgenesfromcross-siteintegrateddatabasedonrelativeexpressionorderings.Int.J.Biol.Sci.2018,14(8):892-900.(DOI:10.7150/ijbs.24548)(JCR三区,IF3.873
3.JunCheng,XuekunSong,LuAo,RouChen,MeirongChi,YouGuo,JiahuiZhang,HongdongLi,WenyuanZhao,ZhengGuo*,XianlongWang*.Sharedliver-liketranscriptionalcharacteristicsinlivermetastasesandcorrespondingprimarycolorectaltumors.J.Cancer2018,9(8):1500-1505.(DOI:10.7150/jca.23017)(JCR三区,IF2.916)
4.LuAo,ZimeiZhang,QingzhouGuan,YatingGuo,YouGuo,JiahuiZhang,XingweiLv,HaiyanHuang,HuarongZhang,XianlongWang,ZhengGuo.Aqualitativesignatureforearlydiagnosisofhepatocellularcarcinomabasedonrelativeexpressionorderings.LiverInternational.2018,38,1812–1819.(DOI:10.1111/liv.13864)(JCR二区,IF4.116)
5.HuapingLiu,YaweiLi,JunHe,QingzhouGuan,RouChen,HaidanYan,WeichengZheng,KaiSong,HaoCai,YouGuo,XianlongWang*andZhengGuo*.Robusttranscriptionalsignaturesforlow-inputRNAsamplesbasedonrelativeexpressionorderings.BMCGenomics.2017,18:913.(DOI:10.1186/s12864-017-4280-7)(JCR二区,IF3.729)
6.JunHe,HaidanYan,HaoCai,XiangyuLi,QingzhouGuan,WeichengZheng,RouChen,HuapingLiu,KaiSong,ZhengGuo*andXianlongWang*.Statisticallycontrolledidentificationofdifferentiallyexpressedgenesinone-to-onecelllinecomparisonsoftheCMAPdatabasefordrugrepositioning.JournalofTranslationalMedicine.2017,15:198.(DOI:10.1186/s12967-017-1302-9).(JCR二区,IF3.786)
7.LuAo,YouGuo,XuekunSong,QingzhouGuan,WeichengZheng,JiahuiZhang,HaiyanHuang,YiZou,ZhengGuo*,XianlongWang*.Evaluatinghepatocellularcarcinomacelllinesfortumorsamplesusingwithin-samplerelativeexpressionorderingsofgenes.LiverInternational.2017,37,1688-1696.(DOI:10.1111/liv.13467).(JCR二区,IF4.116)
8.ShuqinCao,YanpengLiu,HuiShang,SheyuLi,JianJiang,XiaofengZhu*,PengZhang,XianlongWang*,JianshuLi*.Supramolecularnanoparticlesofcalcitoninanddipeptideforlong-termcontrolledrelease.JournalofControlledRelease.2017,256(28):182-192.(DOI:10.1016/j.jconrel.2017.04.014).(JCR一区,IF7.441)
9.PeterABeckmann*,CleliaWMallory,FrankBMallory,ArnoldLRheingold,XianlongWang*.MethoxyandMethylGroupRotation:Solid-StateNMR1HSpin-LatticeRelaxation,ElectronicStructureCalculations,X-rayDiffractometry,andScanningElectronMicroscopy.ChemPhysChem,2015,16(7),1509.DOI:10.1002/cphc.201402716(二区,IF3.138)
10.XianlongWang*,FrankBMallory,CleliaWMallory,HosannaOdhner,PeterABeckmann*.Solidstate1Hspin-latticerelaxationandisolated-moleculeandclusterelectronicstructurecalculationsinorganicmolecularsolids:Therelationshipbetweenstructureandmethylgroupandt-butylgrouprotation.J.Chem.Phys.2014,140(19),194304.DOI:10.1063/1.4874157(二区,IF2.894)