研究领域
主要研究领域:新农药生物合理设计与相关化学生物学研究;药物分子设计、合成与研究;新型杂环化合物的合成与研究;功能有机磷化合物的研究与应用。
近期论文
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Ren Q.Y., Liang Y. J. He H.W*. Fu L.W.* , Gu Y. C. A Facile Synthesis and Biological Activity of Novel Tetrahydrobenzo[4’,5’]thieno[3’,2’:5,6] pyrido[4,3-d]pyrimidin-4(3H)-ones , Bioorganic & Medicinal Chemistry Letters, 2009,19, 6713-6716
Mo W.Y., Liao G. H., Wang T., He H.W*. Facile synthesis and biological activities of novel fluorine-containing pyrido[4,3-d]pyrimidines, Journal of Fluorine Chemistry, 2008, 129 (6): 519-523
Peng H., Wang T., Xie P., Chen T., He H.W* and Wan J*. Molecular Docking and Three-Dimensional Quantitative Structure-Activity Relationship Studies on the Binding Modes of Herbicidal 1-(Substituted Phenoxyacetoxy) alkylPhosphonates to the E1 Component of Pyruvate Dehydrogenase, J. Agric. Food Chem. 2007, 55, 1871-1880
Liu J. C., He H.W*, Ren Q.Y, Ding M. W., Synthesis of derivatives of pyrido[4,3-d]pyrimidin-4(3H)-one via an iminophosphorane,Helv. Chim. Acta, 2006, 89, 1337-1343
He H.W*, Wang T., and Yuan J. L. Synthesis and herbicidal activities of methyl-1-(2,4-dichlorophenoxyacetoxy) alkylphosphonate monosalts , Journal of Organometallic Chemistry, 2005, 690 , 2608-2613