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Design, synthesis, and metabolism studies of N-1,4-diketophenyltriazinones as protoporphyrinogen IX oxidase inhibitors. Liu, H. Y.; Yu, L. K.; Qin, S. N. Yang, H. Z.; Wang, D. W.; * Xi, Z.2023-05-04
Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds. Wang, D.; Pang, Z.; Yu, H.; Thiombiano, B.; Walmsley, A.; Yu, S.; Zhang, Y.; Wei, T.; Liang, L.; Wang, J.; Wen, X.; Bouwmeester, H. J.; Yao, R.; Xi, Z. 2022-03-03
Discovery of a broad-spectrum fluorogenic agonist for strigolactone receptors through a computational approach. Wang, D.-W.; Yu, S.-Y.; Pang, Z.-L.; Ma, D.-J.; Liang, L.; Wang, X.; Wei, T.; Yang, H.-Z.; Ma, Y.-Q.; Xi, Z. 2021-06-09
Discovery of N-phenylaminomethylthioacetylpyrimidine-2,4-diones as protoporphyrinogen IX oxidase inhibitors through a reaction intermediate derivation approach. Wang, D. W.; Liang, L.; Xue, Z. Y.; Yu, S. Y.; Zhang, R. B.; Wang, X.; Xu, H.; Wen, X.; Xi, Z. 2021-06-09
Discovery of a potent thieno[2,3-d]pyrimidine-2,4-dione-based protoporphyrinogen IX oxidase inhibitor through in silico structure-guided optimization approach. Wang, D. W.; Zhang, H.; Yu, S. Y.; Zhang, R. B.; Liang, L.; Wang, X.; Yang, H. Z.; Xi, Z. 2021-06-01
Diaryl Ether: A Privileged Scaffold for Drug and Agrochemical Discovery. Tao Chen, Hao Xiong, Jing-Fang Yang, Xiao-Lei Zhu, Ren-Yu Qu,* and Guang-Fu Yang*2020-08-11
An Activity-based Fluorogenic Probe Enables Cellular and In Vivo Profiling of Carboxylesterase Isozymes. Shi-Yu Liu(共一), Ren-Yu Qu(共一), Rong-Rong Li, Yao-Chao Yan, Yao Sun, Wen-Chao Yang,*,† and Guang-Fu Yang*,†‡ 2020-06-09
Discovery of Novel Pyrazole−Quinazoline-2,4-dione Hybrids as 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. He, B.; Wu, F. X.; Yu, L. K.; Wu, L.; Chen, Q.; Hao, G. F.; Yang, W. C.; Lin, H. Y.;* Yang, G. F.*2020-05-06
Auto in silico ligand directing evolution (AILDE) to facilitate the rapid and efficient discovery of drug lead. Wu, F. X.; Zuo, L. S.; Wang, F.; Huang, W.;* Hao, G. F.;* Yang, G. F.*2020-04-29
In Vivo Imaging of Human Neutrophil Elastase for Pulmonary Diseases based on Fluorescence Resonance Energy Transfer Using CdSe/ZnS Quantum Dots. Yan, A. M.; Liu, S. Y.; Fang, Y. Y.; Dong, Q. J.; Li, R. R.; Sun, Y.; Yang, W. C.;* Yang, G. F.*2020-04-28
Graph attention convolutional neural network accurately predicts chemical poisoning of honey bees. Wang, F.; Yang, J. F.; Wang, M. Y.; Jia, C. Y.; Shi, X. X.; Hao, G. F.;* Yang, G. F.*2020-04-03
Graph attention convolutional neural network model for chemical poisoning of honey bees’ prediction. Fan Wang, Jing-Fang Yang, Meng-Yao Wang, Chen-Yang Jia, Xing-Xing Shi, Ge-Fei Hao, Guang-Fu Yang 2020-04-03
Cross-resistance, biochemical mechanism and fitness costs of laboratory-selected resistance to pyridalyl in diamondback moth, Plutella xylostella. Wang, R.; Qu, C.; Wang, Z. Y.;* Yang, G. F.*2020-02-12
Genome-wide phylogenetic and structural analysis reveals the molecular evolution of the ABA receptor gene family. Yang, J. F.; Chen, M. X.; Zhang, J. H.; Hao, G. F.,* Yang, G. F.*2020-02-07
A drug-likeness toolbox facilitates ADMET study in drug discovery. Jia, C. Y.; Li, J. Y.; Hao, G. F.;* Yang, G. F.2020-01-15
Molecular pathogenesis of tumorigenesis caused by succinate dehydrogenase defect. Moosavi, B.;* Zhu, X. L.; Yang, W. C.; Yang, G. F.*2020-01-15
Fragment-based Discovery of Flexible Inhibitor Targeting Wild-type Acetohydroxyacid Synthase and P197L Mutant. Qu, R. Y.; Yang, J. F.; Chen, Q.; Niu, C. W.; Xi, Z.; Yang, W. C.; Yang, G. F.*2020-01-14
Development of a Web-Based Laboratory Class to Reduce the Challenges in Teaching Fragment-Based Drug Design. Shi, X. X.; Li, J. Y.; Chen, Q.; Hao, G. F.;* Yang, G. F.*2020-01-09
The anti-cancer compound Schweinfurthin A targets Osh2 and disrupts lipid metabolism in yeast model. Moosavi, B.;* Gao, M. Q.; Zhu, X. L.; Yang, G. F.*2020-01-03
An overview of spirooxindole as a promising scaffold for novel drug discovery. Zhou, L. M.; Qu, R. Y.; Yang, G. F.*2020-01-02
Synthesis and Biological Evaluation of New MET Inhibitors with 1,6-Naphthyridinone Scaffold. Wang, M. S.; Zuo, L. S.; Yang, F. P.; Wang, W. J.; Huang, W.;* Yang, G. F.*2020-01-01
LARMD: integration of bioinformatic resources to profile ligand-driven protein dynamics with a case on the activation of estrogen receptor. Yang, J. F.; Wang, F.; Chen, Y. Z.; Hao, G. F.,* Yang, G. F.*2019-12-03
Pyrazole-Isoindoline-1,3-dione Hybrid: A Promising Scaffold for 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. He, B.; Dong, J.; Lin, H. Y.; Wang, M. Y.; Li, X. K.; Zheng, B. F.; Chen, Q.; Hao, G. F.; Yang, W. C.;* Yang, G. F.*2019-09-17