个人简介

Engineering and Physical Sciences Research Council (UK) Grant recipient (2012-2013) National Science Foundation Postdoctoral Fellow (2009-2012) National Science Foundation EAPSI Fellow (2007) National Institutes of Health GPP Biophysics Fellow (2003-2008)

研究领域

Biological/Computational/Theoretical/Physical

Biological Theory and computation of molecular and cellular processes Computational / Theoretical Theory and computation of molecular and cellular processes Physical Theory and computation of molecular and cellular processes

近期论文

查看导师最新文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

D. Nissley and E.P. O'Brien. "Timing is everything: Unifying codon translation rates and nascent proteome behavior" J. Am. Chem. Soc., 2014. 136, 17892-17898. E.P. O'Brien, P. Ciryam, M. Vendruscolo and C. M. Dobson. "Understanding the influence of codon translation rates on cotranslational protein folding" Acc. Chem. Res., 2014. 47, 1536-1544. E.P. O'Brien, M. Vendruscolo and C. M. Dobson. "Kinetic modeling indicates that fast translating codons can coordinate cotranslational protein folding by avoiding misfolding" Nature Communications, 2014. 5, 2988. P. Ciryam, R. I. Morimoto, M. Vendruscolo, C. M. Dobson and E. P. O’Brien. "In vivo translation rates can substantially delay the cotranslational folding of the E. coli cytosolic proteome" Proc. Natl. Acad. Sci. U.S.A., 2013. 110, E132-E140. D. Thirumalai, Z. Liu, E. P. O’Brien and G. Reddy. "Protein folding: From theory to practice" Curr. Opin. Struc. Biol., 2013. 23, 22-29. E. P. O’Brien, J. Christodoulou, M. Vendruscolo and C. M. Dobson. "Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactions" J. Am. Chem. Soc., 2012. 134, 10920-10932. E. P. O’Brien, M. Vendruscolo and C. M. Dobson. "Prediction of variable translation rate effects on co-translational folding" Nature Communications, 2012. 3, 868. E. P. O’Brien, J. Christodoulou, M. Vendruscolo and C. M. Dobson. "New scenarios of protein folding can occur on the ribosome" J. Am. Chem. Soc., 2011. 133, 513-526. E. P. O’Brien, S. T. D. Hsu, J. Christodoulou, M. Vendruscolo and C. M. Dobson. "Transient tertiary structure formation within the ribosome exit port" J. Am. Chem. Soc., 2010. 132, 16928-16937.