甘泉 - 华中科技大学 - 化学与化工学院

个人简介

2013.2-2014.10 剑桥大学，玛丽居里奖学金，博士后（导师： Jonathan Nitschke 教授） 2010.1-2013.3 法国波尔多第一大学和欧洲化学生物学研究所，有机化学专业，博士（导师：Ivan Huc 教授） 2008.9-2012.1 中国科学院化学研究所，有机化学专业，博士（导师：江华研究员） 2005.9-2008.6 华中师范大学，有机化学专业，硕士（导师：刘盛华教授）： 2001.9-2005.6 华中师范大学，应用化学专业，本科

研究领域

主要从事分子仿生研究：在分子层次上，设计合成一系列工螺旋折叠分子和三维笼状化合物，模拟生物体系的结构与功能。通过动态共价组装方式，探索分子间自组装、自分类行为，研究其在识别、催化、分子/离子运输、信息传递、能量转换、以及分子开关、分子机器等方面的应用。

近期论文

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Q. Gan, T. K. Ronson, D. A. Vosburg, J. D. Thoburn, J. R. Nitschke, Cooperative loading and release behavior of a metal-organic receptor, J. Am. Chem. Soc., 2015, 137, 1770−1773. J. Shang, Q. Gan, S. J. Dawson, F. Rosu, H. Jiang, Y. Ferrand, and I. Huc, Self-association of aromatic oligoamide foldamers into double helices in water, Org. Lett., 2014, 16, 4992−4995. Q. Gan, Y. Wang, H.Jiang,Twisted helical microfibers by hierarchical self-assembly of an aromatic oligoamide foldamer, Chin. J. Chem., 2013, 31, 651-656. Q. Gan, Y.Ferrand, N.Chandramouli, B.Kauffmann, C.Aube, D.Dubreuil, I.Huc, Identification of a foldaxane kinetic byproduct during guest-induced single to double helix conversion, J. Am. Chem. Soc., 2012, 134, 15656−15659. Q. Gan, J. Shang, B.Kauffmann, Y. Wang, F. Bie, H.Jiang, A highly stable double helix of aromatic oligoamide comprised of fused ring aromatic units, Tetrahedron, 2012, 68, 4479-4484. Q. Gan,Y. Ferrand, C. Bao, B. Kauffmann, A. Grélard, H. Jiang, I. Huc, Helix-rod host-guest complexes with shuttling rates much faster than disassembly, Science, 2011, 331, 1172-1175. Y. Ferrand, Q. Gan, B. Kauffmann, H. Jiang, I. Huc, Template-induced screw motions within an aromatic amide foldamer double helix, Angew. Chem. Int. Ed., 2011, 50, 7572-7575. Q. Gan, Y. Wang, H. Jiang, Aromatic amide foldamers: A paradigm for structure-property relationships, Curr. Org. Chem., 2011, 15, 1293-1301. Q. Gan, F. Li, G. Li, B. Kauffmann, J. Xiang, I. Huc, H. Jiang, Heteromeric double helix formation by cross-hybridization of chloro-and fluoro-substituted quinoline oligoamides, Chem. Comm., 2010, 46, 297-299. C. Bao, Q. Gan, B. Kauffmann, H. Jiang, I. Huc, A self-assembled foldamer capsule: combining single and double helical segments in one aromatic amide sequence, Chem. Eur. J., 2009, 15, 11530-11536. F. Li, Q. Gan, L. Xue, Z.-M. Wang, H.Jiang, H-bonding directed one-step synthesis of novel macrocyclic peptidesfrom ?-aminoquinolinecarboxylic acid, Tetrahedron Lett., 2009, 50, 2367-2369. Q. Gan, C. Bao, B. Kauffman, A. Grélard, J. Xiang, S. Liu, I. Huc, H. Jiang, Quadruple and double helices of 8-fluoroquinoline oligoamides, Angew. Chem. Int. Ed., 2008, 47, 1715-1718. C. Bao, B. Kauffman, Q. Gan, K. Srinivas, H. Jiang, and I. Huc, Converting sequences of aromatic amino acid monomers into functional three-dimensional structures: second-generation helical capsules, Angew. Chem. Int. Ed., 2008, 47, 4153-4156. H.-H Wang, Q. Gan,X.-J. Wang, L. Xue, S.-H Liu, H. Jiang, A water-soluble, small molecular fluorescent sensor with femtomolar sensitivity for zinc ion, Org. Lett., 2007, 9, 4995-4998.