沈雷 - 武汉理工大学 - 化学化工与生命科学学院

个人简介

1999-2003，中国科学技术大学，化学物理专业，本科 2003-2008，中国科学技术大学&加拿大多伦多大学，博士(联培)，导师：吴奇院士&Prof. Mitchell A. Winnik 2008-2009，瑞士日内瓦大学，博士后，合作导师：Michal Borkovec教授 2009-2012，美国德州大学&明尼苏达大学，博士后，合作导师：Xiaoyang Zhu教授&Timothy Lodge教授 2012-2013，美国哥伦比亚大学，化学系，助理研究员 2013-2016，华中科技大学，化学与化工学院，副教授 2017-现在，武汉理工大学，化学化工与生命科学学院，教授

研究领域

大分子表界面科学：瞄准生命健康，通过科学实验与计算模拟相结合，揭示大分子与表界面微观作用机制，创制生物功能材料。如原创无涂层式一体化小口径(直径<4mm)人工血管，为临床提供可靠的人工血管材料；阐明蛋白与药物分子的动态作用机制，创制高效抗菌促愈合材料；发明与血管相关手术器械，降低临床操作难度和相关并发症等。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

C. Cheng, Y. Zeng, Guanbin Gao*, Taolei Sun*, Lei Shen*. Flexibility Analysis of DNA Nanotubes with Prescribed Circumferences and Their Pearl-necklace Assemblies with Gold Nanoclusters. Langmuir, 2023. Y. Geng, T. Huang, W. Zhou, Lei Shen*. Physical Mechanism of Amyloid-β Peptide Chain Aggregation on Fluidic Lipid Nanotubules. Langmuir, 2022. Guanbin Gao*, X. Liu, Z. Gu, Q. Mu, G. Zhu, T. Zhang, C. Zhang, L. Zhou, Lei Shen*, Taolei Sun*. Engineering Nanointerfaces of Au25-Clusters for Chaperone-Mediated Peptide Amyloidosis. Nano Lett. 2022, 22, 2964. L. Wen, Lei Shen*. Effect of Surface-Chelated Cu2+ on Amyloid-β Peptide Fibrillation. Langmuir, 2022, 38, 174. Y. Song, Y. Geng, Lei Shen*. Visualizing Super-Diffusion, Oligomerization and Fibrillation of Amyloid-β Peptide Chains along Tubular Membranes ACS Macro Lett. 2021, 10, 1295. (Invited as Cover work) X. Zhou, M. Zhao, Y. Y. Liu, Q. J. Chen, Lei Shen*. Statistical Binding Matching Between Influenza-A-Virus and Dynamic Glycan Clusters Determines Its Adhesion onto Lipid Membranes. Langmuir, 2020, 36, 15212. (Invited as Cover work) M. Tian, B. Li*, Lei Shen*. Hierarchical Self-Assembly Mechanism of Ladder-Like Orientated Aβ40 Single-Stranded Protofibrils into Multistranded Mature Fibrils. ACS Macro Lett. 2020, 9, 1759. (Invited as Cover work) M. Tian, Lei Shen*, Self-coiling of single-stranded protofibrils into rings: A pathway of Alzheimer’s beta-peptide amyloidosis on lipid membranes. ACS Macro Lett. 2020, 9, 813. (Invited as Cover work) J. Liu, M. Tian, Lei Shen*, Surface effects on the degree of twist in amyloid fibril structures. Chem. Commun. 2020, 56, 3147. S. Cai, J. Liu, M. Tian, K Wang, Lei Shen*, Diffusion dynamics of a single collapsed homopolymer globule at solid-liquid interface. Soft Matter, 2020, 16, 2431. (Invited as Cover work) S. Gong, J. Liu, M. Tian, K Wang, S. Cai, W. Wang, Lei Shen*, Unravelling the mechanism of amyloid-β peptide oligomerization and fibrillation at chiral interfaces. Chem. Commun., 2019, 55, 13725. P. Li, Y. Shen, L. Wang, W. Lu, W. Li, K. Chen, Y. Zhou, Lei Shen*, F. Wei*, W. Zheng, The electric double layer structure modulates poly-dT25 conformation and adsorption kinetics at the cationic lipid bilayer interface. Soft Matter, 2019, 15, 4445. (Invited as Cover work) J. Lin, K. Wang, X. Xia, Lei Shen*. Quantification of Multivalency in Protein Oligomer Coated Nanoparticles Targeting Dynamic Membrane Glycan Receptors. Langmuir, 2018, 34, 8415. M. Yang, K. Wang, J. Lin, L. Wang, F. Wei*, J. Zhu, W. Zheng, Lei Shen*. Gel phase membrane retards amyloid beta-peptide (1-42) fibrillation by restricting slaved diffusion of peptides on lipid bilayers. Langmuir, 2018, 34, 8408.