黄开勋 - 华中科技大学 - 化学与化工学院

研究领域

（1）硒蛋白的生物学功能，着重于硒蛋白在糖尿病、血管疾病和白内障发生发展中作用及机理；（2）新药制剂及功能食品的研究与开发；（3）无机纳米材料的合成与生物安全性研究。

近期论文

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Hongjie Chen, Weiqun Tian, Kaixun Huang*. Effect of blood-retinal barrier development on formation of selenite nuclear cataract in rat. Toxicology Letters. 216 (2013): 181-188. Yi Li, Yi Ji, Jun Zhou, Kaixun Huang*. Effect of methionine sulfoxide reductase B1 silencing on high-glucose-induced apoptosis of human lens epithelial cells. Life Sciences.92(2013): 193-201 HA Abbood, KAM Ahmed, Y Ren, KX Huang*. MnV2O6?V2O5 cross-like nanobelt arrays: synthesis, characterization and photocatalytic properties. Appl Phys A. (2013) 112: 901-909 Y Jia, Y Li, SQ Du, KX Huang*. Involvement of MsrB1 in the regulation of redox balance and inhibition of peroxynitrite-induced apoptosis in human lens epithelial cells. Experimental Eye Research 100 (2012): 7-16. Hayder A. Abbood, H Peng, XH Gao, BE Tan, KX Huang*. Fabrication of cross-like NH4V4O10 nanobelt array controlled by CMC as soft template and photocatalytic activity of its calcinated product. Chemical Engineering Journal 209 (2012): 245-254. Khalid AM Ahmed, Hayder A. Abbood, KX Huang*. Hydrothermal synthesis of Mn(OH)O nanowires and their thermal conversion to (1D)-manganese oxides nanostructures. Journal of Crystal Growth. 2012, 358: 33-37. Khalid Abdelazez Mohamed Ahmed, Kaixun Huang*. Synthesis, characterization and catalytic activity of birnessite type potassium manganese oxide nanotubes and nanorods. Materials Chemistry and Physics 133 (2012) 605-610. Yi Li, Wen Zhang, Peiwu Li, Kaixun Huang*. Effect of streptozocin-induced diabetes mellitus on expression of methionine sulfoxide reductases and accumulation of their substrates in mouse lenses. Experim Eye Res. 92 (2011) 401-407 Khalid Abdelazez Mohamed Ahmed, Hong Peng, Kangbing Wu, Kaixun Huang*. Hydrothermal preparation of nanostructured manganese oxides (MnOx) and their electrochemical and photocatalytic properties. Chemical Engineering Journal 172 (2011) 531-539 Du SQ, Zhou J, Jia Y, Huang KX* SelK is a novel ER stress-regulated protein and protects HepG2 cells from ER stress agent-induced apoptosis. Arch Biochem Biophys. 2010, 502: 137-143 Du SQ, Liu HM, Huang KX*. Influence of SelS gene silence on β-Mercaptoethanol- mediated endoplasmic reticulum stress and cell apoptosis in HepG2 cells. Biochim Biophys Acta. 2010, 1800: 511-517. Jun Zhou, Kaixun Huang*. Peroxynitrite mediates muscle insulin resistance in mice via nitration of IRβ/IRS-1 and Akt. Toxicology and Applied Pharmacology 2009, 241: 101-110 Zeng, JH, Zhou, J, Huang, KX. Effect of selenium on pancreatic proinflammatory cytokines in streptozotocin-induced diabetic mice. Journal of Nutritional Biochemistry 2009, 20: 530-536 Jun Zhou, Xingmu He, Kaixun Huang*. Bidirectional regulation of insulin receptor autophosphorylation and kinase activity by peroxynitrite. Archives of Biochemistry and Biophysics. 2009, 488: 1-8 Liu HM, Wang TB, Huang KX*. Cholestiane-3 beta,5 alpha,6 beta-triol-induced reactive oxygen species production promotes mitochondrial dysfunction in isolated mice liver mitochondria. Chemico-Biological Interactions, 2009, 179 (2-3): 81-87 Khalid Abdelazez Mohamed Ahmed, Qiumei Zeng, Kangbing Wua, Kaixun Huang*. Mn3O4 nanoplates and nanoparticles: Synthesis, characterization, electrochemical and catalytic roperties, Journal of Solid State Chemistry, 2010, 183(3): 744-751 Jun Zhou, Haidong Li, Jinhong Zeng, Kaixun Huang*. Effects of peroxynitrite-induced protein tyrosine nitration on insulin-stimulated tyrosine phosphorylation in HepG2 cells. Mol Cell Biochem, 2009, 331:49-57 Xue G, Liu FX, Wang Y, Huang KX*. Optimization of Synthetic Conditions for the Preparation of Dihomo-gamma-Linolenic Acid from gamma-Linolenic Acid Journal of the American Oil Chemists Society, 2009, 86 (1): 77-82 Cheng GE, Huang T, Wu K, Huang KX*. Synthesis of Fiber-Like Porous Microstructures SnO2 Templated by Cotton Fibers and Their Gas Sensing Properties Journal of Nanoscience and Nanotechnology, 2009, 9(3): 2001-2007 Zhao PT, Zeng QM, Huang KX. Fabrication of beta-NiS hollow sphere consisting of nanoflakes via a hydrothermal process Materials Letters, 2009, 63 (2): 313-315 Yu Zhang, Kaixun Huang*. DFT studies on the role of glutamate residue in the tyrosine nitration. Journal of Molecular Structure: THEOCHEM. 2008, 864(1-3): 48-55 Jinhong Zeng, Shaoqing Du, Jun Zhou, Kaixun Huang*. Role of SelS in lipopolysaccharide- induced inflammatory response in hepatoma HepG2 cells. Archives of Biochemistry and Biophysics, 2008, 478: 1–6 Guoe Cheng, Tao Huang, Kui Wu and Kaixun Huang*. Synthesis of Fiber-Like Porous Microstructures SnO2 Templated by Cotton Fibers and Their Gas Sensing Properties. Journal of Nanoscience and Nanotechnology, 2008, 8, 1-7 Pingtang Zhao, Qiumei Zeng, Xianliang He, Hao Tang, Kaixun Huang*. Preparation of γ-MnS hollow spheres consisting of cones by a hydrothermal method. Journal of Crystal Growth, 2008, 310: 4268–4272 Liu HM, Liu SX, Huang KX*. Low-temperature chemical route to bismuth-doped tellurium single-crystalline nanorods. Materials Letters, 2008, 62(12-13): 1983-1985 Pingtang Zhao and Kaixun Huang*. Preparation and Characterization of Netted Sphere-like CdS Nanostructures. Crystal Growth & Design. 2008, 8(2): 717–722 Pingtang Zhao, Jinmin Wang, Guoe Chen, Zhou Xiao, Jing Zhou, Dean Chen, and Kaixun Huang*. Hydrothermal Synthesis of PbS Hollow Spheres with Single Crystal-Like Electron Diffraction Patterns. Journal of Nanoscience and Nanotechnology. 2008, 8: 379-385