当前位置: X-MOL首页全球导师 国内导师 › 董海

个人简介

华中科技大学化学化工学院教授, 博士生导师。曾长期在化工企业工作,历任车间工人、技术员、车间生产主管、技术开发主管等职。主持及参与过多项精细化工的技术开发及化工设计。自2004年于瑞典皇家工学院攻读博士学位后,开始从事生物有机化学,特别是糖化学领域的研究工作。曾获得2008年国家优秀自费留学生奖学金。2009年入职华中科技大学化学化工学院。现已在国际知名期刊如JACS,Angew,CC,GC,ECJ,ASC,JOC,OBC等以第一作者或通讯作者发表糖化学领域研究论文五十多篇。总引用次数1000多次,H因子为20。多次在国际学术会议做报告。先后主持两项国家自然科学基金面上项目。申请发明专利五项,获授权三项,并已向企业转让授权专利两项。 教育经历 [1] 2004.9~2009.2 瑞典皇家工学院 - 哲学博士学位 - 研究生(博士)毕业 [2] 1997.9~1999.7 郑州大学 - 硕士学位 - 研究生(硕士)毕业 [3] 1988.9~1992.7 南京化工学院 - 学士学位 - 本科(学士)

研究领域

1.高效的糖基化方法及糖羟基的选择性保护方法. 2.具有生物活性的多糖的合成. 3.糖芯片的研发及应用. 4.硫糖合成及其生物活性测试 5.动态组合化学在生物医药研究中的应用. 6.生物多糖能源转化的研究. 7.糖精细化工产品的开发应用.

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

冯广京,吴钰周,罗涛,吕剑,王双双.董海.Improved Synthesis of 1-Glycosyl Thioacetates and Its Application in the Synthesis of Thioglucoside Gliflozin Analogues.Eur. J. Org. Chem. 2021, 2940–2949, Xueming Li,Yuxin Pei,Quanquan Song.Zhichao Pei,Teodor Aastrup,Hai Dong.Direct attachment of suspension cells to PDA surface and its application in suspension-cell QCM biosensor.Sens. Actuators B Chem. 2021, 326, 128823, 张乐峰,葛建涛,张英,蒲亮.董海,裴志超.The Oxidation of S-Acetyl by Nitrite: Mechanism and Application.ChemistrySelect 2020, 5, 14549, 吕剑,罗涛,冯广京,余剑成.董海.Stannous chloride as a low toxicity and extremely cheap catalyst for regio-/site-selective acylation with unusually broad substrate scope.[J].Green Chem., 2020, 22, 6936, 罗涛,张英,Jiafeng Xi.董海,卢玉超.Improved Synthesis of Sulfur-Containing Glycosides by Suppressing Thioacetyl Migration.[J].Front. Chem. 2020, 8, 319, 刘瑜,吕剑,朱家佳,邹大鹏.董海.Regio/site-selective alkylation of substrates containing a cis-, 1,2- or 1,3-diol with ferric chloride and dipivaloylmethane as the catalytic system..[J].Green Chem. 2020, 22, 1139-1144, 朱家佳,吕剑,刘瑜.董海.Regioselective Sulfonylation/Acylation of Carbohydrates Catalyzed by FeCl3 Combined with Benzoyltrifluoroacetone and Its Mechanism Study..[J].J. Org. Chem. 2020, 85, 3307-3319, 吕剑,罗涛,邹大鹏.董海.Using DMF as Both a Catalyst and Cosolvent for the Regioselective Silylation of Polyols and Diols.[J].Eur. J. Org. Chem. 2019, 6383-6395, Yuchao Lu, Chenxi Hou, Jingli Ren, Kui Yang, Yincheng Chang, Yuxin Pei, Hai Dong, Zhichao Pei.董海,裴志超.A multifunctional supramolecular vesicle based on complex of cystamine dihydrochloride capped pillar[5]arene and galactose derivative for targeted drug delivery.[J].Int. J. Nanomedicine. 2019. 14. 3525, 葛建涛,吕剑,罗涛,周琅.董海.A One-Pot Method for Removal of Thioacetyl Group via Desulfurization under Ultraviolet Light to Synthesize Deoxyglycosides..[J].Org. Lett. 2019, 21, 5903-5906, Ying Zhang, Fu-Long Zhao, Tao Luo, Zhichao Pei.Zhichao Pei, Hai Dong.Regio/Stereoselective Glycosylation of Diol and Polyol Acceptors in Efficient Synthesis of Neu5Ac‐α‐2,3‐LacNPhth Trisaccharide.[J].Chem. Asia J. 2019, 14, 223, Jian Lv, Tao Luo, Ying Zhang, Zhichao Pei.Zhichao Pei, Hai Dong.Regio/Site-Selective Benzoylation of Carbohydrates by Catalytic Amounts of FeCl3.[J].ACS Omega 2018, 3, 17717, Bo Ren, Lu Gan, Li Zhang, Ningning Yan, Hai Dong.Bo Ren.Publication Preview Source Diisopropylethylamine-Triggered, Highly Efficient, Self-Catalyzed Regioselective Acylation of Carbohydrates and Diols.Org. Biomol. Chem. 2018, 16, 5591, Bo Ren, Jiantao Ge, Hai Dong.Hai Dong.Reply to the ‘Comment on “Zemplén transesterification: a name reaction that has misled us for 90 years”’ by G. Poli, C. Pezzetta, I. Leito and S. Tshepelevitsh, Green Chemistry, 2018, 20, DOI: 10.1039/c7gc03795c.[J].Green Chem. 2018, 20, 2395, Jian Lv, Jian-Tao Ge, Tao Luo, Hai Dong.Hai Dong.An inexpensive catalyst, Fe(acac) 3 , for regio/site-selective acylation of diols and carbohydrates containing a 1,2- cis -diol.[J].Green Chem. 2018, 20, 1987, Jian-Tao Ge, Lang Zhou, Fu-Long Zhao,Hai Dong*.Hai Dong.Straightforward S−S Bond Formation via the Oxidation of S‑Acetylby Iodine in the Presence of N‑Iodosuccinimide.[J].J. Org. Chem. 2017, 82, 12613., Oscar Norberg, Bin Wu, Niranjan Thota, Jian-Tao Ge, Germain Fauquet, Ann-Kathrin Saur, Teodor Aastrup, Hai Dong,* Olof Ramstrom.Hai Dong,* Mingdi Yan,* Olof Ramstrom*.,Synthesis and binding affinity analysis of alpha 1-2-and alpha 1-6-O/S-linked dimannosides for the elucidation of sulfur in glycosidic bonds using quartz crystal microbalance sensors, Carbohydr. Res. 2017, 452, 35..[J]. Jian-Tao Ge, Ying-Ying Li, Jun Tian, Rong-Zhen Liao, Hai Dong*.Hai Dong.Synthesis of Deoxyglycosides by Desulfurization under UV Light.J. Org. Chem. 2017, 82, 7008., Hengfu Xu,Ying Zhang, Hai Dong,* Yuchao Lu, Yuxin Pei, Zhichao Pei,*.Hai Dong,* Zhichao Pei*.Organotin-catalyzed regioselective benzylation of carbohydrate trans-diols,.Tetrahedron Lett. 2017, 58, 4039., Bo Ren, Jian Lv, Yu Zhang, Jun Tian, Hai Dong,*.Hai Dong*.Highly Efficient Selective Benzylation of Carbohydrates Catalyzed by Iron(III) with Silver Oxide and Bromide Anion as Co-catalysts,.ChemCatChem, 2017, 9, 950., Yuchao Lu, Chenxi Hou, Jingli Ren, Xiaoting Xin, Hengfu Xu, Yuxin Pei, Hai Dong*, Zhichao Pei*..Hai Dong*, Zhichao Pei*.Regioselective Benzoylation of Diols and Carbohydrates by Catalytic Amounts of Organobase..[J].Molecules, 2016, 21, 641., Hengfu Xu, Bo Ren, Wei Zhao, Xiaoting Xin, Yuchao Lu, Yuxin Pei, Hai Dong*, Zhichao Pei*..Hai Dong*, Zhichao Pei*.Regioselective mono and multiple alkylation of diols and polyols catalyzed by organotin and its applications on the synthesis of value-added carbohydrate intermediates..Tetrahedron 2016, 72, 3490., Xueming Li, Siyu Song, Yuxin Pei, Hai Dong*, Teodor Aastrup, Zhichao Pei*..Hai Dong*, Zhichao Pei*.Oriented and reversible immobilization of His-tagged proteins on two- and three-dimensional surfaces for study of protein-protein interactions by a QCM biosensor..Sens. Actuators B: Chem. 2016, 224, 814., Bo Ren, Olof Ramström, Qiang Zhang, Jiantao Ge, Hai Dong*..Hai Dong*.An Iron(III) Catalyst with Unusually Broad Substrate Scope in Regioselective Alkylation of Diols and Polyols..[J].Chem. Eur. J. 2016, 22, 2481., Chen Shao, Xueming Li, Zhichao Pei, Dongdong Liu, Lin Wang, Hai Dong*, Yuxin Pei*..Hai Dong*, Yuxin Pei*.Facile fabrication of glycopolymer-based iron oxide nanoparticles and their applications in carbohydrate-lectin interaction and targeted cell imaging..[J].Polym. Chem. 2016, 7, 1337., Xiaoling Zhang, Bo Ren, Jiantao Ge, Zhichao Pei*.Zhichao Pei*, Hai Dong*..A Green and Convenient Method for Regioselective Mono and Multiple Benzoylation of Diols and Polyols..[J].Tetrahedron. 2016, 72, 1005., Bin Wu, Jiantao Ge, Bo Ren, Zhichao Pei*, Hai Dong*..Zhichao Pei*, Hai Dong*.Synthesis and Binding Affinity Analysis of Positional Thiol Analogs of Mannopyranose for the Elucidation of Sulfur in Different Position..[J].Tetrahedron, 2015, 71, 4023., Bo Ren, Meiyan Wang, Jingyao Liu, Jiantao Ge, Hai Dong*.Hai Dong*.Enhanced Basicity of Ag2O by Coordination to Soft Anions..[J].ChemCatChem 2015, 7, 761, Jingyi Li, Lingzhi Chen, Jiangping Xu, Ke Wang, Xiaofan Wang, Xiaohua He, Hai Dong.Hai Dong,* Shaoliang Lin,*,Jintao Zhu*.Photoguided Shape Deformation of Azobenzene-Containing Polymer Microparticles,.[J].Langmuir 2015, 31, 13094., Bo Ren, Meiyan Wang, Jing-yao Liu, Jiantao Ge, Xiaoling Zhang, Hai Dong*..Hai Dong*.Zemplén Transesterification: A Name Reaction Having Been Misleading Us for 90 Years..[J].Green Chem. 2015, 17, 1321.,

推荐链接
down
wechat
bug