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个人简介

张宪省,博士、教授、博士生导师,山东农业大学校长,作物生物学国家重点实验室主任。担任中国植物学会植物细胞生物学专业委员会副主任,中国遗传学会理事,山东省遗传学会理事长,山东省植物学会副理事长,美国植物生物学会会员。《PlantCellReports》副主编,《植物学报》和《遗传》编委。 教学工作 承担本科生《生物技术科学进展》、《生物科学研究进展》;硕士研究生《植物发育分子生物学》、《发育生物学专业外语》;博士研究生《生命科学研究进展》、《发育生物学专题讨论》等。

研究领域

研究方向 1.植物发育的分子基础:本研究方向主要研究植物开花时间、有性生殖、种子发育等植物发育的重要科学问题,尤其是研究植物细胞全能性和器官发育的分子机制。目的旨在解析上述发育过程的基因调控网络,阐明植物发育的细胞分子基础。 2.植物生物技术:本研究方向主要分离控制重要农艺性状的基因,改良小麦和玉米的重要农艺性状和品质性状,提高作物产量,改良作物品质。

科研项目 1.转基因生物新品种培育重大专项:玉米叶片功能期延长和粒重增加等转基因新材料和新组合筛选(2016ZX08003003-002),2016-2020年。 2.重大科学研究计划项目(973):植物传粉与受精的分子调控网络(2013CB945100),2013-2017年。 3.国家自然科学基金重大研究计划:生长素和细胞分裂素调节离体器官发生的分子调控网络(91217308),2013-2015年。 4.转基因生物新品种培育重大专项:高产转基因玉米新品种培育(2014ZX08003-003),2014-2015年。 5.山东省农业良种工程:高产优质彩糯小麦种植材料创新与新品种培育,2013-2015年。 6.重大科学研究计划项目(973计划):植物授粉细胞识别的分子机理研究信号通路(2007CB947600),2007-2011年。 7.国家自然科学基金重点项目:植物激素调节体细胞胚胎发生的分子机理研究(90917015),2010-2013年。 8.重大科学研究计划项目(973):植物干细胞维持和分化的分子机理研究(2007CB948200),2007-2011年。 9.转基因生物新品种培育重大专项:高产转基因玉米新品种培育(2013ZX08003-003),2013年。 10.转基因生物新品种培育重大专项:高产转基因玉米新品种培育(2011ZX08003-003),2011-2012年。 11.转基因生物新品种培育重大专项课题:高产转基因玉米新品种培育(2008ZX08003-003),2008-2010年。 12.重大科学研究计划项目(973计划):植物干细胞维持和分化的分子机理研究(2007CB948200),2007-2011年。 研究专利 1.小麦TaTOC1基因及其克隆方法和应用,专利号:ZL201110093145.7。 2.一种用于改良玉米株型和提高玉米产量的基因的获得方法和应用,专利号:ZL201310653350.3。 3.小麦TaGI1基因及其克隆与应用,专利号:ZL200410035916.7。 4.紫花苜蓿Na+/H+反向转运蛋白基因及其克隆与应用,专利号ZL200410035915.2。 5.紫色小麦二氢黄酮醇还原酶基因及其克隆与应用,专利号ZL200410035914.8。 6.小麦周期蛋白基因及其分离方法与应用,专利号ZL02135544.4。 7.偃麦草钠离子反向转运蛋白基因及其克隆方法与应用,专利号ZL02135545.2。 8.山农紫糯1号,农业部新品种保护权。 9.山农紫糯2号,审核中,农业部新品种保护权。

近期论文

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1.ChengZJ1,ZhaoXY1,ShaoXX1,WangF,ZhouC,LiuYG,ZhangYandZhangXS(2014)AbscisicAcidRegulatesEarlySeedDevelopmentinArabidopsisbyABI5-MediatedTranscriptionofSHORTHYPOCOTYLUNDERBLUE1,Plantcell,26:1053-1068. 2.SuYHandZhangXS(2014)TheHormonalControlofRegenerationinPlants.InBrigitteGalliot,editor:MechanismsofRegeneration,108:35-69 3.LiYL,DaiXR,YueX,GaoXQandZhangXS(2014)Identificationofsmallsecretedpeptides(SSPs)inmaizeandexpressionanalysisofpartialSSPgenesinreproductivetissues.Planta,240:713-728 4.DaiXR1,GaoXQ1,ChenGH,TangLL,WangHandZhangXS(2014)ABNORMALPOLLENTUBEGUIDANCE1,anendoplasmicreticulum-localizedmannosyltransferasehomologofGLYCOSYLPHOSPHATIDYLINOSITOL10inyeastandPHOSPHATIDYLINOSITOLGLYCANANCHORBIOSYNTHESISBinhuman,isrequiredforArabidopsispollentubemicropylarguidanceandembryodevelopment.PlantPhysiology,165:1544–1556 5.YueX1,GaoXQ1,WangFandZhangXS(2014)Transcriptionalevidenceforinferredpatternofpollentube-stigmametaboliccouplingduringpollination.PLoSOne,9(9):e107046.DOI:10.1371/journal.pone.0107046 6.BaiB,SuYH,YuanJandZhangXS(2013)InductionofSomaticEmbryosinArabidopsisRequiresLocalAuxinBiosynthesisMediatedbytheDown-regulationofEthyleneBiosynthesis.MolecularPlant,6:1247-1260 7.SuYH,SuYX,LiuYGandZhangXS(2013)AbscisicacidisrequiredforsomaticembryoinitiationthroughmediatingspatialauxinresponseinArabidopsis.PlantGrowthRegul.69:167-176 8.ZhaoXY,SuYH,ZhangCL,WangL,LiXGandZhangXS(2013)DifferencesincapacitiesofinvitroorganregenerationbetweentwoArabidopsisecotypesWassilewskijaandColumbia.PlantCellTissOrganCult112:65-74 9.LiXM,SangYL,ZhaoXYandZhangXS(2013)High-ThroughputSequencingofSmallRNAsfromPollenandSilkandCharacterizationofmiRNAsasCandidateFactorsInvolvedinPollen-SilkInteractionsinMaize.PLoSOne,8:e72852 10.XuXH,WangF,ChenH,SunWandZhangXS(2013)TranscriptomeAnalysisofMaizeSilksRevealsEffectiveActivationofGenesInvolvedinMicrotubule-basedMovement,Ubiquitin-dependentProteinDegradation,andTransportinthePollinationProcess.PLoSOne,8:e53545 11.ChengZJ,WangL,SunW,ZhangY,ZhouC,SuYH,LiW,SunTT,ZhaoXY,LiXG,ChengY,ZhaoY,XieQandZhangXS(2012)PatternofauxinandcytokininresponsesforshootmeristeminductionresultsfromtheregulationofcytokininbiosynthesisbyAUXINRESPONSEFACTOR3.PlantPhysiol.161:240-251 12.XuXH1,ChenH1,SangYL,WangF,MaJP,GaoXQandZhangXS(2012)Identificationofgenesspecificallyorpreferentiallyexpressedinmaizesilkrevealssimilarityanddiversityintranscriptabundanceofdifferentdrystigmas.BMCGenomics13:294-310 13.SangYL,XuM,MaFF,ChenH,XuXH,GaoXQandZhangXS(2012)Comparativeproteomicanalysisrevealssimilaranddistinctfeaturesofproteinsindryandwetstigmas.Proteomics12:1983-1998 14.GaoXQandZhangXS.(2012)MetabolismandRolesofPhosphatidylinositol3-phosphateinPollenDevelopmentandPollenTubeGrowthinArabidopsis.PlantSiganlingandBehavior7:2,1-5 15.XuN,GaoXQ,ZhaoXY,ZhuDZ,ZhouLZandZhangXS(2011)ArabidopsisAtVPS15isEssentialforPollenDevelopmentandGerminationthroughModulatingPhosphatidylinositol3-PhosphateFormation.PMB77(3):251-60 16.LiW,LiuH,ChengZJ,SuYH,HanHN,ZhangYandZhangXS(2011)DNAMethylationandHistoneModificationsRegulatedenovoShootRegenerationinArabidopsisbyModulatingWUSCHELExpressionandAuxinSignaling.PlosGenetics7:8el002243 17.SuYH,LiuYBandZhangXS(2011)Auxin-cytokinininteractionregulatesmeristemdevelopment.MolecularPlant4(4):616-625 18.LiX,ChenGH,ZhangWYandZhangXS(2010)Genome-widetranscriptionalanalysisofmaizeendosperminresponsetoaewxdoublemutation.JGG.37:749-762 19.SuYH,ChengZJ,SuYXandZhangXS(2010)PatternanalysisofstemcelldifferentiationduringinvitroArabidopsisorganogenesis.Front.Biol.5(5):464-470 20.ChengZJ,ZhuSS,GaoXQandZhangXS(2010)CytokininandauxinregulatesWUSinductionandinflorescenceregenerationininvitroinArabidopsis.PlantCellRep29:927-933. 21.GaoXQ,ZhuDZandZhangXS(2010)Stigmafactorsregulatingself-compatiblepollination.Front.Biol.5(2):156-163 22.LiXG,SuYH,ZhaoXY,LiW,GaoXQandZhangXS(2010)Cytokininoverexpression-causedalterationofflowerdevelopmentispartiallymediatedbyCUC2andCUC3inArabidopsis.Gene450:109-120 23.GuoJ,WangF,SongJandZhangXS(2010)TheexpressionofOrysa;CycB1;1isessentialforendospermformationandcausesembryoenlargementinrice.Planta231:293-303 24.MaY,WangF,GuoJandZhangXS(2009)RiceOsAS2Gene,aMemberofLOBDomainFamily,FunctionsinRegulationofShootDifferentiationandLeafDevelopment.JournalofPlantBiology52:374-381 25.SuYH,ZhaoXY,LiuYB,ZhangCL,O’NeillSDandZhangXS(2009)Auxin-inducedWUSexpressionisessentialforembryonicstemcellrenewalduringsomaticembryogenesisinArabidopsis.PlantJournal59:448-460 26.SuYHandZhangXS(2009)Auxingradientstriggerdenovoformationofstemcellsduringsomaticembryogenesis.PlantSignalingandBehavior4:7,574-576 27.ZhouY,ZhangXJ,KangXJ,ZhaoXY,ZhangXSandNiM(2009)SHORTHYPOCOTYLUNDERBLUE1associateswithMINISEED3andHAIKU2promotesinvivotoregulateArabidopsisseeddevelopment.PlantCell21:106-117 28.MaQ,DaiX,XuY,GuoJ,LiuY,ChenN,XiaoJ,ZhangD,XuZ,ZhangXSandChongK.(2009)EnhancedtolerancetochillingstressinOsMYB3R-2transgenicriceismediatedbyalterationincellcycleandectopicexpressionofstressgenes.PlantPhysiology150:257-271 29.LuoY,LiuYB,DongYX,GaoXQandZhangXS.(2009)ExpressionofaputativealfalfahelicaseincreasestolerancetoabioticstressinArabiodopsisbyenhancingthecapacitiesforROSscavengingandosmoticadjustment.JournalofPlantPhysiology166:385-394 30.WangB,SangY,SongJ,GaoXQandZhangXS.(2009)ExpressionofariceOSARGOSgeneinArabidopsispromotescelldivisionandexpensionandincreasesorgansize.J.Genet.Genomics36:31-40 31.SunZ,MaL,MurphyRW,ZhangXSandHuangDW.(2009)Factorsaffectingmito-nuclearcodonusageinteractionsintheOXPHOsystemofDrosophilamelanogaster.J.Genet.Genomics35:729-735 32.SunZ,WanDG,MurphyRW,MaL,ZhangXSandHuangDW.(2009)Comparisonofbasecompositionandcodonusageininsectmitochondrialgenomes.Genes&Genomics31:65-71 33.于明明,李兴国,张宪省。APETALA1启动子驱动AtPT4在转基因拟南芥中表达导致花和花器官发育异常。植物学报44(1):59-68 34.WuXQ,LiXGandZhangXS.(2008)Molecularanalysisofhormone-regulatedpedalregenerationinPetunia.PlantCellReports27:1169-1176 35.ZhaoXY,SuYH,ChengZHandZhangXS.(2008)Cellfateswitchduringinvitroplantorganogenesis.JournalofIntergrativePlantBiology50(7):814-822 36.AnBY,LuoY,LiJR,QiaoWH,ZhangXSandGaoXQ.(2008)ExpressionofavacuolarNa+/H+antiportorgeneofalfalfaenhancessalinitytoleranceintransgenicArabidopsis.ActaAgronomicaSinica34:557-564 37.GuoJ,SongJ,WangFandZhangXS.(2007)Genome-wideidentificationandexpressionanalysisofricecellcyclegenes.PlantMolecularBiology64:349-360 38.QiaoWH,ZhaoXY,LiWandZhangXS.(2007)Characterizationofaroot-specificvacuolarNa+/H+antiportergeneinAgropyronelongatumanditsexpressioninvolvedinthesalttoleranceofplants.PlantCellReports26:1663-1672 39.DongYX,ZhaoXY,WangJW,YuanGLandZhangXS.(2007)ImprovementforAgronomicTraitsofPartialWaxyWheatbyCombinationofBackcrossingwithaPCR-basedDNAMarker.JournalofGenet.Genomics34:836-841 40.GuoSJ,ZhouHY,ZhangXS,LiXGandMengQW.(2007)OverexpressionofCaHSP26intransgenictobaccoalleviatesphotoinhibitionofPSIIandPSIduringchillingstressunderlowirradiance.JournalofPlantPhysiology164:126-136 41.ChuZQ,ChenH,ZhangYY,ZhangZH,ZhengNY,YinBJ,YanHY,ZhuL,ZhaoXY,YuanM,ZhangXSandXieQ.(2007)KnockoutoftheAtCESA2geneaffectsmicrotubuleorientationandcausesabnormalcellexpansioninArabiodpsisthaliana.PlantPhysiology143:213-224 42.MaXJ,TaoY,ZhaoXYandZhangXS.(2007)WheatTaAS2,amemberofLOB-Domainfamily,affectstheadaxial-abaxialpolarityofleavesintransgenicArabidopsis.PlantScience172:181-188 43.WangF,HuoSN,GuoJandZhangXS.(2006)WheatD-TypecyclinTriae;CYCD2;1regulatedevelopmentoftransgenicArabidopsisplants.Planta224:1129-1140 44.GuanCM,ZhuSS,LiXGandZhangXS.(2006)Hormone-regulatedinflorescenceinductionandTFL1expressioninArabidopsiscallusinvitro.PlantCellReports25:1133-1137 45.ZhaoW,SuHY,SongJ,ZhaoXYandZhangXS.(2006)EctopicexpressionofTaYAB1,amemberofYABBYgenefamilyinwheat,causesthepartialabaxializationoftheadaxialepidermisesofleavesandarreststhedevelopmentofshootapicalmeristeminArabidopsis,PlantScience170:364-371 46.GuoSJ,LiJR,QiaoWHandZhangXS.(2006)Analysisofamyloseaccumulationduringseeddevelopmentofmaize.ActaGeneticaSinica32:846-854 47.ZhaoXY,LiuMS,LiJR,GuanCMandZhangXS.(2005)ThewheatTaGI1,involvedinphotoperoidicflowering,encodesanArabidopsisGIortholog.PlantMolecularBiology58:53-64 48.ZhaoXY,ChengZJandZhangXS.(2006)OverexpressionofTaMADS1,aSEPALLATA-likegeneinwheat,causesearlyfloweringandtheabnormaldevelopmentoffloralorgansinArabidopsis.Planta223:698-707 49.SuHY,LiQZ,LiXGandZhangXS.(2005)CharacterizationandexpressionanalysisofaMADSboxgene,HoMADS2,inHyacinthusorientalisL.ActaGeneticaSinica32:1191-1198 50.LiuMS,WangF,DongYXandZhangXS.(2005)Expressionanalysisofdihydroflavonol4-reductasegenesinvolvedinanthocyaninbiosynthesisinpurplegrainsofTriticumaestivum.JournalofIntergrativePlantBiology47(9):1107-1114 51.LiJR,ZhaoW,LiQZ,YeXG,AnBY,LiXandZhangXS.(2005)RNASilencingofwaxygeneresultsinlowlevelsofamyloseintheseedsoftransgenicwheat(TriticumaestivumL.).ActaGeneticaSinica32:846-854 52.XuHY,LiXG,LiQZ,BaiSN,LuWLandZhangXS.(2004)CharacterizationofHoMADS1anditsinductionbyplanthormonesduringinvitrodevelopmentinHyacinthusorientalisL.PlantMolecularBiology55:209-220 53.LanLF,ChenW,LaiY,SuoJF,KongZS,CanLi,LuY,ZhangYJ,ZhaoXY,ZhangXS,ZhangYS,HanB,ChengJandXueYB.(2004)Mornitoringofgeneexpressionprofilesandisolationofcandidategenesinvolvedinpollinationandfertilizationinrice(OryzasativaL.)using10KcDNAmicroarray.PlantMolecularBiology54:471-483 54.AnYR,LiXG,SuHYandZhangXS.(2004)PistilinductionbyhormonesfromcallusofOryzasativainvitro.PlantCellReports23:448-452 55.LiJR,WangF,ZhaoXY,DongYX,ZhangLY,AnBYandZhangXS.(2004)AnalysisofSeedExpressedSequenceTagsinTriticumaestivum.ActaBotanicaSinica46(3):363-370 56.ZhangXS,WangX,LiQZ,HuoSN,LiXGandYeBX.(2003)Aseed-specificgeneRS6,encodesaputativecupindomainprotein,isessentialforseeddevelopmentinOryzasativaL.TheAnnualMeetingoftheAmericanSocietyofPlantBiologists,PlantBiology,Abstractp49 57.LiQZ,LiXG,BaiSN,LuWLandZhangXS.(2002)IsolationofHAG1anditsregulationbyplanthormonesduringinvitrofloralorganogenesisinHyacinthusorientalisL.Planta215:533-540 58.LiQZ,LiXG,BaiSN,LuWLandZhangXS.(2001)IsolationandexpressionofHAP2inHyacinthusorientalisL.Development&ReproductiveBiology10:69-75 59.ZhangXS,LiQZ,LiXG,BaiSNandLuWL.(2000)MolecularcloningandexpressionanalysisofHAG1inthefloralorgansofHyacinthusorientalisL.ScienceinChinaC,2000,43:395-401 60.ZhangXS,LiQZ,LiXG,BaiSNandLuWL.(2000)RegulationofhomeoticgeneexpressionintheregeneratedflowersofHyacinthus.PlantBiology,TheAnnualMeetingoftheAmericanSocietyofPlantPhysiologists80:p39 61.LiQZ,LiXG,SunJQandZhangXS.(2000)IsolationandexpressionofanAGAMOUShomologintheflowerofCucumber(CucumissativasL.).Development&ReproductiveBiology9:69-76 62.ZhangXS,ZhengCCandO'NeillSD.(1999)Expressionofethylenebiosyntheticgenesregulatedbypollination-associatedfactorsinDoritaenopsisflowers.ActaBotanicaSinica41(5):468-471 63.ZhengCCandZhangXS.(1999)Cloningandcharacterizationofacircadianrhythm-regulatedpsaHcDNAinPharbitisnil.ActaBotanicaSinica41(8):820-824 64.ZhangXS,LiQZandZhengCC.(1999)HormonalregulationofpostpollinationdevelopmentofDoritaenopsisflowersbyauxinandethylene.ActaPhytophysiologicaSinica25(2):178-186 65.WangL,ZhangXS,ZhongHWandLiQZ.(1999)ExpressionandsequenceanalysisofacDNArelativetoOrchidovuledevelopment.ActaBotanicaSinica41(3):276-279 66.NadeauJA,ZhangXS,LiJandO'NeillSD.(1996)Ovuledevelopment:Identificationofstage-specificandtissue-specificcDNAs.PlantCell8:213-239 67.O'NeillSD,ZhangXSandZhengCC.(1994)DarkandcircadianregulationofmRNAaccumulationassociatedwithphotoperiodicflowerinduction.PlantPhysiology104:569-580 68.ZhangXS,NadeauJA,LiJandO'NeillSD.(1994)IsolationofcDNAclonesspecifictodevelopingandmatureovulesoforchidflowers.PlantPhysiology124:Supplement 69.ZhangXSandO'NeillSD.(1993)Ovaryandgametophytedevelopmentarecoordinatelyregulatedbyauxinandethylenefollowingpollination.PlantCell5:403-418 70.NadeauJA,ZhangXS,NairHandO'NeillSD.(1993)Temporalandspatialregulationof1-aminocyclopropane-1-carboxylateoxidaseinthepollination-inducedsenescenceoforchidflowers.PlantPhysiology103:31-39 71.O'NeillSD,NadeauJA,ZhangXS,BuiAQandHallevyAH.(1993)Interorganregulationofethylenebiosyntheticgenesbypollination.PlantCell5:419-432

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