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Biological Malaria parasite metabolism and biochemistry Document Actions

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Lisewski AM, Quiros JP, Ng CL, Adikesavan AK, Miura K, Putluri N, Eastman RT, Scanfeld D, Regenbogen SJ, Altenhofen L, Llinás M, Sreekumar A, Long C, Fidock DA, Lichtarge O."Supergenomic Network Compression and the Discovery of EXP1 as a Glutathione Transferase Inhibited by Artesunate." Cell. 2014 Aug 14;158(4):916-28. doi: 10.1016/j.cell.2014.07.011. Coleman BI, Skillman KM, Jiang RH, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BF, Marti M, Llinás M, Buckee CO, Duraisingh MT. "A Plasmodium falciparum Histone Deacetylase Regulates Antigenic Variation and Gametocyte Conversion." Cell Host & Microbe. 2014 Aug 13;16(2):177-86. doi: 10.1016/j.chom.2014.06.014. (Read Highlight Summary from Cell Host & Microbe) Oberstaller J, Pumpalova Y, Schieler A, Llinás M, Kissinger JC. "The Cryptosporidium parvum ApiAP2 gene family: insights into the evolution of apicomplexan AP2 regulatory systems." Nucleic Acids Research. 2014 June 23. pii: gku500. O’Hara JK, Kerwin LJ, Cobbold SA, Tai J, Bedell TA, Reider PJ, Llinás M. "Targeting NAD+ metabolism in the human nalaria parasite Plasmodium falciparum." PLoS ONE. 2014 April; 9(4):e94061. (Supplement) Kafsack BFC, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA, Cortés A, Llinás M. "A transcriptional switch underlies commitment to sexual development in malaria parasites." Nature. 2014 Mar 13;507(7491):248-52. (Supplement) (Read Highlight Summary in Current Biology) (Read Highlight Summary in Nature Reviews Microbiology) (Read Review on Sexual Commitment by Pietro Alano) Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R, Kafsack BFC, Williams AE, Llinás M, Berriman M, Billker O, Waters AP. "A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium." Nature. 2014 Mar 13;507 (7491):253-7. (Supplement) Lewis IA, Wacker M, Olszewski KL, Cobbold SA, Baska KS, Tan A, Ferdig MT, Llinás M. "Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism." PLoS Genetics. 2014 Jan;10(1):e1004085. (Supplement) Klein EY, Graham AL, Llinás M, Levin S. "Cross-reactive immune responses as primary drivers of malaria chronicity". Infection & Immunity. 2014 Jan;82(1): 140-51. (Supplement) Cobbold SA, Vaughan AM, Lewis IA, Painter HJ, Camargo N, Perlman DH, Fishbaugher M, Healer J, Cowman AF, Kappe SH, Llinás M. "Kinetic Flux Profiling Elucidates Two Independent Acetyl-CoA Biosynthetic Pathways in Plasmodium falciparum". J Biol Chem. 2013 Dec 20; 288(51): 36338-50. (Supplement) Caudy AA, Guan Y, et al. "A new system for comparative functional genomics of Saccharomyces yeasts." Genetics. 2013 Sep; 195(1): 275-87. Mira-Martínez S, Rovira-Graells N, Crowley VM, Altenhofen LM, Llinás M, Cortés A. "Epigenetic switches in clag3 genes mediate blasticidin S resistance in malaria parasites". Cellular Microbiology. 2013 Nov;15(11): 1913-23. Carter LM, Kafsack B, Llinás M, Pollitt L, Reece S "Stress and Sex in Malaria Parasites: Why Does Commitment Vary?" Evolution, Medicine, and Public Health. 2013 June 4; 135-147. Radke JB, Lucas O, De Silva EK, Ma Y, Sullivan WJ Jr, Weiss LM, Llinás M, White MW. "ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst." PNAS 2013 April 09. Pino P, Sebastian S, Kim EA, Bush E, Brochet M, Volkmann K, Kozlowski E, Llinás M, Billker O, Soldati-Favre D. "A tetracycline-repressible transactivator system to study essential genes in malaria parasites." Cell Host & Microbe 2012 Dec 13;12(6):824-34. Babbitt SE, Altenhofen L, Cobbold SA, Istvan ES, Fennell C, Doerig C, Llinás M, Goldberg DE. "Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state." PNAS 2012 Nov 20;109(47):E3278-87. Painter HJ, Altenhofen LM, Kafsack BF, Llinás M. "Whole-Genome Analysis of Plasmodium spp. Utilizing a New Agilent Technologies DNA Microarray Platform." Methods Mol Biol. 2012 923:213-9. Olszewski KL, Llinás M. "Extraction of Hydrophilic Metabolites from Plasmodium falciparum-Infected Erythrocytes for Metabolomic Analysis." Methods Mol Biol. 2012 923:259-66. Straimer J, Lee MC, Lee AH, Zeitler B, Williams AE, Pearl JR, Zhang L, Rebar EJ, Gregory PD, Llinás M, Urnov FD, Fidock DA. "Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases." Nature Methods. 2012 Aug 2. Kafsack BF, Painter HJ, Llinás M. "New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community." Malaria Journal. 2012 Jun 8;11(1):187. Painter HJ, Llinás M. "Comment on "emerging functions of transcription factors in malaria parasite." J Biomed Biotechnol. 2012 Epub 2012 May 20. Klein EY, Lewis IA, Jung C, Llinás M, Levin SA. "Relationship between treatment-seeking behaviour and artemisinin drug quality in Ghana." Malaria Journal. 2012 Apr 6;11:110.

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