张蕊 - 鲁东大学

个人简介

2010.7-至今鲁东大学农学院副教授 2007.9-2010.7 中国科学院西北高原生物研究所特种资源研究中心获理学博士学位 2004.9-2007.8 曲阜师范大学化学与化工学院任助教、讲师 2001.9-2004.7 山东大学胶体与界面化学教育部重点实验室获理学硕士学位 1997.9-2001.7 曲阜师范大学化学与化工学院获理学学士学位

研究领域

主要研究药用真菌中活性成分的开发利用以及活性成分与相关生物大分子的相互作用。近年来特别关注有毒大型真菌中各类毒素及其它活性成分的分离、生物活性研究，同时研究这些活性成分与相关蛋白的相互作用机制

近期论文

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Rui Zhang, Yongfei Ming & Yongjun Liu Long time molecular dynamic simulation on the agonist binding and activation of the β2-adrenergic receptor Molecular Simulation, 2015, 41(7): 564-571 Wenyou Zhu, Yongjun Liu*, Rui Zhang. A QM/MM study of the reaction mechanism of (R)-hydroxynitrile lyases from Arabidopsis thaliana (AtHNL). Proteins, 2015, 83, 66-77. 张蕊*(通讯), 吴超仪, 刘宇, 杨树德, 程显好. 分子对接和荧光光谱法研究麦角甾醇与牛血清白蛋白的相互作用, 食品科学, 2015, 36(23): 38-42 Xiang Sheng, Yongjun Liu, Rui Zhang A theoretical study of the catalytic mechanism of oxalyl-CoA decarboxylase, an enzyme for treating urolithiasis Royal Society of Chemistry Advances, 2014, 4, 35777-35788 Wenyou Zhu, Yongjun Liu, Rui Zhang QM/MM study of the conversion mechanism of lysine to methylornithine catalyzed by methylornithine synthase (PyIB) Theoretical Chemistry Accounts, 2013, 132: 1385 ZHANG Rui, DONG Li-hua, LING Bao-ping, Wang Zhi-guo, Liu Yong-jun Activation of β2-Adrenergic Receptor Induced by Three Catecholamine Agonists: a Docking and Molecular Dynamics Study Chemical Research in Chinese Universities, 2012, 28(3), 493-499. 张蕊, 杨树德, 程显好, 包海鹰, 图力古尔鹅膏毒肽与RNA聚合酶II相互作用的分子机制研究菌物学报, 2012, 31(5):727-735. 张蕊, 图力古尔鹅膏毒肽与RNA聚合酶II相互作用的研究进展食用菌学报, 2012, 19(2), 111-116. Ru Qiao, Rui Zhang, Weiqun Zhu, Peijun Gong Lab simulation of profile modification and enhanced oil recovery with a quaternary ammonium cationic polymer Journal of Industrial and Engineering Chemistry, 2012, 18, 111-115 Rui Zhang, Zhiguo Wang, Baoping Ling, Yongjun Liu, Chengbu Liu Docking and molecular dynamics studies on the interaction of four imidazoline derivatives with potassium ion channel (Kir6.2) Molecular Simulation, 2010, 36(2), 166-174. Baoping Ling, Rui Zhang, Zhiguo Wang, Yongjun Liu*, Changqiao Zhang, Chengbu Liu Theoretical studies on the interaction of guanine riboswitch with guanine and its closest analogs Molecular Simulation, 2010, 36(12), 929-938. BAOPING LING, RUI ZHANG, ZHIGUO WANG, YONGJUN LIU, CHENGBU LIU STUDY ON THE INTERACTIONS OF Smac MIMETICS WITH XIAP-BIR3 DOMAIN BY DOCKING AND MOLECULAR DYNAMICS SIMULATIONS Journal of Theoretical and Computational Chemistry, 2010, 9(4), 797–812 张蕊, 凌宝萍, 孟祥华, 王志国, 张长桥, 刘永军, 刘成卜咪唑啉类药物与钾离子通道Kir6.2相互作用的分子对接研究高等学校化学学报, 2009, 30(11), 2266-2271.