李霞 - 华中农业大学 - 植物科学技术学院

个人简介

学习经历 1981.09-1985.07 河北师范大学生物学，本科学生，获得理学学士学位 1988.09-1991.06 河北师范大学，硕士研究生，获得理学硕士学位 1998.01-2001.06 美国普渡大学园艺系博士研究生，获得博士学位工作经历 1985.07-1988.08 河北师范大学生物系（现生命学院）党总支秘书 1991.06-1992.06 河北师范大学生物系，助教 1992.06-1995.08 河北师范大学生物系，讲师，植物教研室副主任 1995.09-1997.12 美国普渡大学生物系和园艺系，访问学者 2001.06-2004.02 美国夭科特烟草公司，科学家（研究员） 2004.03-2015.08 中国科学院遗传与发育生物学研究所和植物细胞和染色体工程国家重点实验室，研究员，博士生导师。农业资源研究中心副主任，中心学术委员会主任 2015.9-至今华中农业大学，植物科学技术学院, 教授,博士生导师

研究领域

1.大豆共生固氮调控机理研究大豆是重要的经济作物，是植物蛋白和油脂的主要来源。大豆可以和根瘤菌共生形成根瘤，进而把空气中的N2转化为植物可以利用的NH3。大豆根瘤的发育和固氮效率的高低是影响大豆产量和品质的关键因素。本课题组利用生理生化、分子生物学、遗传学等综合研究方法对大豆根瘤发育和固氮效率及其对非生物胁迫响应的分子机制进行系统性研究，重点研究大豆miRNA及靶基因影响大豆根瘤发育和固氮效率的分子调控网络。旨在解析豆科植物共生固氮的分子机制，为分子设计培育高效固氮的高产优质豆科植物新品种提供科学依据。 2.植物耐逆和可塑性发育分子机制研究植物对逆境响应以及抗逆的分子机制是一个重要的生物学问题，涉及到植物在逆境下的可塑性发育、基础代谢以及植物细胞、组织和个体得能量、水分、离子、氧化还原物的稳态的调控等生物学过程。本课题组将以模式植物拟南芥和大豆为材料，采用综合研究手段探究植物对非生物逆境尤其抗盐碱和干旱响应的生理和遗传机理，重点是植物根系发育对逆境适应和调控分子网络，逆境条件下植物防御代谢的转换的机制。最终目标是揭示植物抗逆的分子机理，创建耐盐抗旱节水新作物品系

近期论文

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1. Wang LX, Sun ZX, Su C, Wang YL, Yan QQ, Chen JH, Ott T, Li X*. (2019). A GmNINa-miR172c-NNC1 regulatory network coordinates the nodulation and autoregulation of nodulation pathways in soybean. Molecular Plant 12: 1211-1226. 2. Wang YN, Yang W, Zuo YY, Zhu L, Hastwell AH, Chen L, Tian Y, Su C, Ferguson BJ, Li X*. (2019). GmYUC2a mediates auxin biosynthesis during root development and nodulation in soybean. Journal of Experimental Botany 70: 3165-3176. 3. Ullah I, Magdy M, Wang LX, Liu MY, Li X*. (2019). Genome-wide identification and evolutionary analysis of TGA transcription factors in soybean. Scientific Reports 9: 11186. 4. Bao A, Chen H, Chen L, Chen S, Hao Q, Guo W, Qiu D, Shan Z, Yang Z, Yuan S, Zhang C, Zhang X, Liu B, Kong F, Li X, Zhou X, Tran LP, Cao D. (2019) CRISPR/Cas9-mediated targeted mutagenesis of GmSPL9 genes alters plantarchitecture in soybean. BMC Plant Biology. 8;19(1):131 5. Sun ZX, Su C, Yun JX, Jiang Q, Wang LX, Wang YN, Cao D, Zhao F, Zhao QS, Zhang MC, Zhou B, Zhang L, Kong FJ, Liu BH, Tong YP, Li X*. (2018). Genetic improvement of the shoot architecture and yield in soybean plants via the manipulation of GmmiR156b. Plant Biotechnology Journal 17: 50-62. 6. Yan Q, Wang LX, Li X*. (2018). GmBEHL1, a BES1/BZR1 family protein, negatively regulates soybean nodulation. Scientific Reports 8: 7614. 7. Ji HT, Wang SF, Cheng CH, Li R, Wang ZJ, Jenkins GI, Kong FJ, Li X*. (2018). The RCC1 family protein SAB1 negatively regulates ABI5 through multidimensional mechanisms during post-germination in Arabidopsis. New Phytologist 222: 907-922. 8. Tang T, Yu XW, Yang H, Gao Q, Ji HT, Wang YX, Yan GB, Peng Y, Luo HF, Liu KD, Li X, Ma CZ, Kang CY, Dai C. (2018). Development and validation of an effective CRISPR/Cas9 vector for efficiently isolating positive transformants and transgene-free mutants in a wide range of plant species. Frontier in Plant Science 9: 1533. 9. Cai ZM#, Wang YN#, Zhu L, Tian YP, Chen L, Sun ZX, Ullah I, Li X*. (2017). GmTIR1/GmAFB3-based auxin perception regulated by miR393 modulates soybean nodulation, New Phytologist 215: 672-686. 10. Hussain RM, Ali M, Feng X, Li X* (2017). The essence of NAC gene family to the cultivation of drought-resistant soybean (Glycine max L. Merr.) cultivars. BMC Plant Biology 17: 55. 11. Sahito ZA, Wang L, Sun Z, Yan QQ, Zhang XK, Jiang Q, Ullah I, Tong YP, Li X*. (2017). The miR172c-NNC1 module modulates root plastic development in response to salt in soybean. BMC Plant Biology 17: 229. 12. Wang YN, Yuan JH, Yang W, Zhu L, Su C, Wang XD, Wu HY, Sun ZX, Li X*. (2017). Genome wide identification and expression profiling of ethylene receptor genes during soybean nodulation. Frontier in Plant Science 8: 859. 13. Cheng CH, Wang ZJ, Ren ZY, Zhi LY, Yao B, Su C, Liu L, Li X*. (2017). SCFAtPP2-B11 modulates ABA signaling by facilitating SnRK2.3 degradation in Arabidopsis thaliana. PLoS Genetics 13: e1006947. 14. Cheng CH, Wang ZJ, Yuan BJ, Li X*. (2017). RBM25 mediates abiotic responses in Plants. Frontier in Plant Science 8: 292. 15. Zheng X, Liu HP, Ji HT, Wang YN, Dong BD, Qiao YZ, Liu MY*, Li X*. (2016). The wheat GT factor TaGT2L1D negatively regulates drought tolerance and plant development. Scientific Reports 6: 27042. 16. Su C#, Liu L#, Liu HP, Ferguson BJ, Zou YM, Zhao YK, Wang T, Wang YN*, Li X*. (2016). H2O2 regulates root system architecture by modulating the polar transport and redistribution of auxin. Journal of Plant Biology 59: 260-270. 17. Sun ZX#, Wang YN#, Mou FP, Tian YP, Chen L, Zhang SL, Jiang Q, Li X*. (2016). Genome- wide small RNA analysis of soybean reveals auxin-responsive microRNAs that are differentially expressed in response to salt stress in root apex. Frontier in Plant Science 6: 1273. 18. Wang ZJ, Ji HT, Yuan BJ, Wang SF, Yao BJ, Su C, Li X*. (2015). ABA signalling is fine-tuned by antagonistic HAB1 variants. Nature Communications 6: 8138