研究领域
(1)过渡金属催化有机合成;(2)活性天然产物的合成,结构修饰和构效关系研究。
近期论文
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Long Yuhua; She zhigang; liu Xiaochen, Chen, Yu*. Synthesis of 1-Aminoisoquinolines by Gold(III)-Mediated Domino Reactions from 2-Alkynylbenzamides and Ammonium Acetate. J. Org. Chem. 2013,78,2579-2588.
Huang, Xishan; Huang, Hongbo; Li, Hanxiang; Sun, Xuefeng; Huang, Huarong; Lu, Yongjun; Lin, Yongcheng; Long, Yuhua*; She, Zhigang *. Asperterpenoid A, a New Sesterterpenoid as an Inhibitor of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B from the Culture of Aspergillus sp. 16-5c. Org. Lett. 2013,15,721-723.
Chen, Hong; Zhu, Xun; Zhong, Li-Li; Yang, Bing; Li, Jia; Wu, Jue-Heng; Chen, Sheng-Ping; Lin, Yong-Cheng; Long, Yuhua*; She, Zhi-Gang* . Synthesis and antitumor activities of derivatives of the marine mangrove fungal metabolite deoxyBostrycin. Marine Drugs,2012,10,2715-2728.
Long, Yuhua; Zhang, Haifeng; Yang, Dingqiao. Efficient Synthesis of Ferrocenylquinolines via the Friedlander Reaction. Synth. Comm.,2013, 43 ,619-634.
Chen, Hong; Zhong, Lili; Long, Yuhua; Li, Jia; Wu, Jueheng; Liu, Lan; Chen, Shengping; Lin, Yongcheng; Li, Mengfeng; Zhu, Xun; She, Zhigang* . Studies on the synthesis of derivatives of marine-derived Bostrycin and their structure-activity relationship against tumor cells. Marine Drugs, 2012, 10 ,932-952.
Wang, Wenling; Long, Yuhua; Zou, Zhifu; Yang, Dingqiao. A Facile Synthesis of Enantiomerically Pure (R)-6-Arylbinols. Chin. J. Chem., 2012, 30, 1092-1096.
Fang, Shai; Liang, Xiuli; Long, Yuhua; Li, Xiaolu; Yang, Dingqiao; Wang, Sanyong; Li, Chunrong. Iridium-Catalyzed Asymmetric Ring-Opening of Azabicyclic Alkenes with Phenols. Organometallics, 2012, 31, 3113-3118.
Long, Yuhua; Yang, Dingqiao*; Zhang, Zhenming; Wu, Yujuan; Zeng, Heping; Chen, Yu*. Iridium-Catalyzed Asymmetric Ring Opening of Azabicyclic Alkenes by Amines. J. Org. Chem. 2010, 75, 7291-7299.
Yang, DingQiao*; Long, YuHua*; Wu, YuJuan; Zuo, XiongJun; Tu, QingQiang; Fang, Shai; Jiang, LaSheng; Wang, San-Yong; Li, Chun-Rong . Iridium-Catalyzed Anti-Stereocontrolled Asymmetric Ring Opening of Azabicyclic Alkenes with Primary Aromatic Amines, Organometallics,2010, 29, 5936-5940.
Yang, Dingqiao*; Long, Yuhua*; Zhang, Junfang; Zeng, Heping; Wang, Sanyong; Li, Chunrong. Iridium-Catalyzed Asymmetric Ring-Opening Reactions of Oxabenzonorbornadienes with Amine Nucleophiles. Organometallics, 2010, 29(16), 3477-3480.
Long, Yuhua; Zhao, Shuangqi; Zeng, Heping; Yang, Dingqiao*. Highly Efficient Rhodium-Catalyzed Asymmetric Ring-Opening Reactions of Oxabenzonorbornadiene with Amine Nucleophiles. Catal. Lett. , 2010 , 138 , 124-133.
Long, Yuhua; Yang, Dingqiao; Zeng, Heping; Xie, Lei; Wu, Lihuan; Mo, Haihong; Zuo, Xiongjun. Rhodium-catalyzed asymmetric ring-opening reactions of N-boc-azabenzonorbornadiene with N-substituted piperazine nucleophiles. Chin. J. Chem. 2010, 28, 235-242.
Yang, Dingqiao*; Long, Yuhua; Wang, Huan; Zhang, Zhenming. Iridium-Catalyzed Asymmetric Ring-Opening Reactions of N-Boc-azabenzonorbornadiene with Secondary Amine Nucleophiles. Org. Lett. 2008, 10, 4723-4726.
Pang, Ji-Yan; Long, Yu-Hua (并列第一); Chen, Wen-Hua; Jiang, Zhi-Hong . Amplification of DNA-binding affinities of protoberberine alkaloids by appended polyamines. Bioorg. & Med. Chem. Lett. 2007, 17, 1018-1021.
Long, Yu-Hua; Bai, Li-Ping; Qin, Yong; Pang, Ji-Yan; Chen, Wen-Hua; Cai, Zongwei; Xu, Zun-Le; Jiang, Zhi-Hong . Spacer length and attaching position-dependent binding of synthesized protoberberine dimers to double-stranded DNA. Bioorg. & Med. Chem. 2006, 14, 4670-4676.