个人简介
张艳,女,博士,副教授。2006年毕业于沈阳药科大学中药学院中药制药专业,并于2006年到2012年期间攻读本校天然药物化学硕士及博士学位。2012年6月博士毕业,并于同年8月留校任教。2015年1月开始在沈阳药科大学博士后流动站从事在职博士后的科研工作,并于2018年入选辽宁省“百千万人才工程”万人层次,同年12月直聘为沈阳药科大学副教授,并聘为硕士生导师。作为课题负责人主持国家自然科学基金青年基金项目1项、国家博士后科学基金特别资助1项、辽宁省自然科学基金面上项目1项;此外,作为项目骨干成员参与国家自然科学基金面上项目及青年项目5项。近年在Foodchemistry、EuropeanJournalofMedicinalChemistry等杂志上发表SCI论文20余篇,目前主要协助宋少江教授培养研究生和开展科研工作。
研究领域
研究方向一:天然先导化合物的发现
研究方向二:天然药物药效作用机制研究
近期论文
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1.WenbaoWang,WeiWang,GuodongYao,QiangRen,DiWang,ZedanWang,PengLiu,PinyiGao,YanZhang*,ShaojieWang*,ShaojiangSong*.Novelsarsasapogenin-triazolylhybridsaspotentialanti-Alzheimer'sagents:Design,synthesisandbiologicalevaluation.EuropeanJournalofMedicinalChemistry,2018,151:351-362.(IF=4.816)
2.GuodongYao#,QianSun#,XiaoyuSong,XiaoxiaoHuang,YanZhang*,ShaojiangSong*.1,3-DiphenylpropanesfromDaphnegiraldiiinducedapoptosisinhepatocellularcarcinomacellsthroughnuclearfactorkappa-Binhibition.BioorganicChemistry,2018,77:619-624.(IF=3.929)
3.YanZhang,WeiWang,HuanHe,XiaoyuSong,GuodongYao,ShaojiangSong*.TriterpenesaponinswithneuroprotectiveeffectsfromawildvegetableAraliaelata.JournalofFunctionalFoods,2018,45:313-320.(IF=3.47)
4.WeiWang#,GuoDongYao#,XinYueShang,JiChaoGao,YanZhang*,ShaoJiangSong*.EclalbasaponinIfromAraliaelata(Miq.)Seem.reducesoxidativestressinducedneuralcelldeathbyautophagyactivation.Biomedicine&Pharmacotherapy,2018,97:152-161.(IF=3.457)
5.YanZhang,YingPeng,LingzhiLi,LeiZhao,YanHu,ChongHu,ShaojiangSong*.StudiesoncytotoxictriterpenesaponinsfromtheleavesofAraliaelata.FoodChemistry,2013,138:208-213.(IF=3.259)
6.YanZhang,LuZhao,ShunwangHuang,WeiWang,ShaojiangSong*.TriterpenesaponinswithneuroprotectiveeffectsfromtheleavesofDiospyroskakiThunb.Fitoterapia,2018,129:138-144.(IF=2.642)
7.YanZhang,ZhiqiangMa,ChongHu,LihuiWang,LingzhiLi,ShaojiangSong*.CytotoxictriterpenesaponinsfromtheleavesofAraliaelata.Fitoterapia,2012,83:806-811.(IF=2.642)
8.YanZhang,FengyingHan,JieWu,ShaojiangSong*.Triterpenesaponinswitha-glucosidaseandPTP1BinhibitoryactivitiesfromtheleavesofAraliaelata.PhytochemistryLetters,2018,26:179-183.(IF=1.575)
9.YanZhang,WeiyuZhou,XiaoyuSong,GuodongYao,ShaojiangSong*.NeuroprotectiveterpenoidsfromtheleavesofViburnumodoratissimum.NaturalProductResearch,2018.(IF=1.928)
10.HuanHe,XinyueShang,WeiweiLiu,YanZhang*,ShaojiangSong*.TriterpenesfromthefruitofCamptothecaacuminatasuppresshumanhepatocellularcarcinomacellproliferationthroughapoptosisinduction.NaturalProductResearch,2018.(IF=1.928)