华会明 - 沈阳药科大学

个人简介

华会明，女，博士，教授。1987年毕业于北京医科大学，获药学学士学位，1990年毕业于沈阳药科大学获药物化学硕士学位，1999年于同校获天然药物化学博士学位。2002-2003年在美国密西西比大学作访问学者。作为课题负责人主持了“十一五”新药创制重大专项1项、国家自然科学基金面上项目3项，以及省市级科研项目20余项。目前已在Org.Lett.,J.Nat.Prod.,Phytochemistry,Eur.J.Med.Chem.,RSCAdvances,J.Func.Foods,Tetrahedron等期刊发表SCI论文130余篇。申请专利19项，授权9项。

研究领域

研究方向一：中药抗肿瘤活性成分研究及先导化合物的发现研究方向二：微生物活性代谢产物研究

近期论文

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1.Kai-BoWang,Da-HongLi,PingHu,Wen-JingWang,ClementLin,JianWang,BinLin,JiaoBai,Yue-HuPei,Yong-KuiJing,Zhan-LinLi*,DanzhouYang*,andHui-MingHua*.ASeriesofβ‑carbolinealkaloidsfromtheseedsofPeganumharmalashowG-quadruplexinteractions.OrganicLetters,2016,18,3398−3401(IF=6.732) 2.Chun-MeiSai,Da-HongLi,Chun-MeiXue,Kai-BoWang,PingHu,Yue-HuPei,JiaoBai,Yong-KuiJing,Zhan-LinLi*,Hui-MingHua*.TwopairsofenantiomericalkaloiddimersfromMacleayacordata.OrganicLetters,2015,17,4102-4105(IF=6.732) 3.Kai-BoWang,Ying-TongDi,YuBao,Chun-MaoYuan,GangChen,Da-HongLi,JiaoBai,Hong-PingHe,Xiao-JiangHao,Yue-HuPei,Yong-KuiJing,Zhan-LinLi,*Hui-MingHua*.PeganumineA,aβ-carbolinedimerwithanewoctacyclicscaffoldfromPeganumharmala.OrganicLetters,2014,16,4028-4031.(IF=6.732) 4.KangtaoTian#,FanxingXu#,XiangGao,TongHan,JiaLi,HuaqiPan*,LingheZang,DahongLi*,ZhanlinLi,TakahiroUchita,MingGao,HuimingHua*.Nitricoxide-releasingderivativesofbrefeldinAaspotentandhighlyselectiveanticanceragents.EuropeanJournalofMedicinalChemistry,2017,136,131-143.(IF=3.902) 5.TongHan,JiaLi,JingjingXue,HeLi,FanxingXu*,KeguangCheng,DahongLi*,ZhanlinLi,MingGao,HuimingHua*.Scutellarinderivativesasapoptosisinducers:Design,synthesisandbiologicalevaluation.EuropeanJournalofMedicinalChemistry,2017,135;270-281(IF=3.902) 6.Kai-BoWang,Da-HongLi,YuBao,FeiCao,Wen-JingWang,ClementLin,WenBin,JiaoBai,Yue-HuPei,Yong-KuiJing,DanzhouYang,Zhan-LinLi*,Hui-MingHua*.StructurallydiversealkaloidsfromtheseedsofPeganumharmala.JournalofNaturalProducts,2017,80(2):551-559.(IF=3.662) 7.Chun-MeiSai,Da-HongLi,Sheng-GeLi,TongHan,Yong-ZhiGuo,Yue-HuPei,JiaoBai,Yong-KuiJing,Zhan-LinLi*,Hui-MingHua*.RacemicalkaloidsfromMacleayacordata:StructuralElucidation,chiralresolution,andcytotoxic,antibacterialactivities.RSCAdvances,2016,6,41173–41180(IF=3.289) 8.YanBai,DahongLi,TingtingZhou,NingboQin,ZhanlinLi,ZhiguoYu*,HuimingHua*.CoumarinsfromtherootsofAngelicadahuricawithantioxidantandantiproliferativeactivities.JournalofFunctionalFoods,2016,20,453–462(IF=3.973) 9.PingHu,DahongLi,KaiboWang,HaoWang,ZihouWang,ZhanlinLi,HuimingHua.NewphenoliccompoundsfromVitexnegundovar.heterophyllaandtheirantioxidantandNOinhibitoryactivities.JournalofFunctionalFoods.2015,19:174-181(IF=3.973) 10Zhi-GuoLiu,Zhan-LinLi*,JiaoBai,Da-LiMeng,NingLi,Yue-HuPei,FengZhao*,Hui-MingHua*.Anti-inflamatoryditerpenoidsfromtherootsofEuphorbiaebracteolata.JournalofNaturalProducts,2014,77,792-799(IF=3.662)

学术兼职

1.入选辽宁省百千万人才工程百人系列； 2.辽宁特聘教授； 3.中国植物学会植物化学与资源学专业委员会委员； 4.中国药学会海洋药物专业委员会委员； 5.世界中医药学会联合会中药化学专业委员会常务理事； 6.辽宁省中药学会理事； 7.辽宁省药学会中药和天然药物专业委员会委员