池岛乔 - 沈阳药科大学 - 无涯创新学院

个人简介

池岛乔，男，博士，教授，博士生导师。1972年毕业于日本东北大学，获理学部生物学科学士学位，1974年于同校获理学研究科硕士学位，1978年获日本东北大学理学研究科博士学位。曾在日本横滨市立大学医学部、美国哈佛大学医学部、Tufts大学医学部任教，此后在日本万有制药株式会社（美国Merck公司的分公司）分子生物学研究所担任部长。1996年来到中国，在长春中医药大学担任教授，于2002年开始在沈阳药科大学任教。现为中日医药研究所所长。作为课题负责人主持了国家自然科学基金面上项目一项，作为主要参与人参与国家自然科学基金三项，辽宁省创新团队项目一项。在沈阳药科大学从事免疫药理学工作10余年来（2002年-），共发表SCI收录论文约200篇，学会发表论文约100篇（其中国际学会80余篇）

研究领域

天然药物有效成分的抗炎、抗肿瘤、抗阿尔兹海默病及抗糖尿病药理学研究天然药物影响细菌凋亡、自噬和衰老等过程的药理学研究细胞外基质胶原明胶对细胞生理学和药理学的影响研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.Zhang X1,Chen YR1,Zhao YL2,Liu WW1,Hayashi T3,Mizuno K4,Hattori S4,Fujisaki H4,Ogura T4,Onodera S5,Ikejima T6. (2019) Type I collagen or gelatin stimulates mouse peritoneal macrophages to aggregate and produce pro-inflammatory molecules through upregulated ROS levels.Int Immunopharmacol.27;76:105845. doi: 10.1016/j.intimp.2019.105845. [Epub ahead of print] (IF=3.361) 2.Liu X1,Long X1,Gao Y1,Liu W1,Hayashi T1,2,Mizuno K3,Hattori S3,Fujisaki H3,Ogura T3,Onodera S4,Wang DO1,Ikejima T1,(2019)Type I collagen inhibits adipogenic differentiation via YAP activation in vitro.J Cell Physiol.. doi: 10.1002/jcp.29100. [Epub ahead of print] (IF=4.522) 3.Sun Y1,Yang J1,2,Liu W1,Yao G3,4,Xu F1,Hayashi T1,5,Onodera S6,Ikejima T7,8(2019) Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha.Mol Cell Biochem.460(1-2):81-92. doi: 10.1007/s11010-019-03572-1. (IF=2.884) 4.Liu B1,Liu W1,Liu P1,Liu X1,Song X1,2,Hayashi T1,3,Onodera S4,Ikejima T5,6.(2019)Silibinin Alleviates the Learning and Memory Defects in Overtrained Rats Accompanying Reduced Neuronal Apoptosis and Senescence.Neurochem Res.44(8):1818-1829. doi: 10.1007/s11064-019-02816-2. (IF=2.782) 5.Si L1,Liu W1,Hayashi T2,Ji Y1,Fu J1,Nie Y1,Mizuno K3,Hattori S3,Onodera S4,Ikejima T5.(2019) Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment.Arch Biochem Biophys.671:42-51. doi: 10.1016/j.abb.2019.05.009. (IF=3.559) 6.Yang J1,2,Sun Y1,Liu X1,Xu F1,Liu W1,Hayashi T1,3,Imamura Y3,Mizuno K4,Hattori S4,Tanaka K4,Fujisaki H4,Tashiro SI5,Onodera S6,Ikejima T1,7.(2019)Silibinin's regulation of proliferation and collagen gene expressions of rat pancreatic β-cells cultured on types I and V collagen involves β-catenin nuclear translocation.Connect Tissue Res.60(5):463-476. doi: 10.1080/03008207.2019.1593393.(IF=2.167) 7.Yang J1,Sun Y1,Xu F1,Liu W1,Hayashi T1,2,Hattori S3,Ushiki-Kaku Y3,Onodera S4,Tashiro SI5,Ikejima T1,6.(2019)Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ1-42 -induced reactive oxygen species/reactive nitrogen species generation.Phytother Res.33(4):998-1009. doi: 10.1002/ptr.6293.(IF=3.766) 8.Zang L1,Wang J2,Ren Y2,Liu W2,Yu Y2,Zhao S2,Otkur W2,Zhao Y2,Hayashi T2,Tashiro SI3,Onodera S4,Ikejima T5.(2019)Activated toll-like receptor 4 is involved in oridonin-induced phagocytosis via promotion of migration and autophagy-lysosome pathway in RAW264.7 macrophages.Int Immunopharmacol.66:99-108. doi: 10.1016/j.intimp.2018.11.014.(IF=3.361) 9.Zhao YL1,Zhang X1,Liu WW1,Yang YT1,Gao ZK1,Liu XL1,Liu W1,Hayashi T1,Yamato M2,Fujisaki H3,Hattori S3,Mizuno K3,Atsuzawa Y3,Tashiro SI4,Onodera S5,Ikejima T1.(2019)Reactive oxygen species are responsible for the cell aggregation and production of pro-inflammatory mediators in phorbol ester (PMA)-treated U937 cells on gelatin-coated dishes through upregulation of autophagy.Connect Tissue Res.2019 Jul;60(4):323-334. doi: 10.1080/03008207.2018.1530770.(IF=2.167) 10.Yang J1,Sun Y1,Xu F1,Liu W1,Mai Y1,Hayashi T1,2,Hattori S3,Ushiki-Kaku Y3,Onodera S4,Tashiro SI5,Ikejima T6.(2019)Silibinin ameliorates amylin-induced pancreatic β-cell apoptosis partly via upregulation of GLP-1R/PKA pathway.Mol Cell Biochem.452(1-2):83-94. doi: 10.1007/s11010-018-3414-9.(IF=2.884)