个人简介
郭兴杰,女,博士,教授。1982年2月毕业于沈阳药学院,获药学学士学位,1991年在沈阳药科大学获药物分析学硕士学位,2003年在沈阳药科大学获得药物分析学博士学位。2001年至2012年,在日本东京大学学习,完成了博士毕业论文的全部研究工作。2013年被聘为沈阳药科大学教授。作为课题负责人主持3项国家自然科学基项目,主持2项国家自然基金理科基础人才项目和2项科技部项目。另外,作为项目骨干成员承担国家自然科学基金面上项目1项,承担国家科技部项目1项。目前已在Talanta等SCI收载期刊发表论文40多篇。
研究领域
研究方向一:手性药物分离新技术、新方法研究。
研究方向二:药物质量控制方法研究。
研究方向三:手性药物在生物体内立体选择性药代动力学研究。
近期论文
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1.LinlinFang,PingWang,XiaoliWen,XinGuo,LindaLuo,JiaYuandXingjieGuo.Layer-by-layerself-assemblyofgoldnanoparticles/thiolsβ-cyclodextrincoatingasthestationaryphaseforenhancedchiraldifferentiationinopentubularcapillaryelectrochromatography.[J].Talanta,2017,167:158-165.(IF4.035)
2.XinGuo,ZhiqiangWang,LihuaZuo,ZhixuZhou,XingjieGuo,TieminSun.Quantitativepredictionofenantioseparationusingβ-cyclodextrinderivativesaschiralselectorsincapillaryelectrophoresis.,Analyst,2014,139(24):6511-6519.(IF4.033)
3.LinlinFang,JiaYu,ZhenJiangandXingjieGuo.Preparationofaβ-Cyclodextrin-BasedOpen-TubularCapillaryElectrochromatographyColumnandApplicationforEnantioseparationsofTenBasicDrugs.[J].PlosOne,2016,11(1):1-11.(IF3.057)
4.JinxiaWei,LinlinFang,XinleiLiang,DanSu,XingjieGuo.AsensitiveandselectiveUPLC–MS/MSmethodforsimultaneousdeterminationof10alkaloidsfromRhizomaMenispermiinratplasmaanditsapplicationtoapharmacokineticstudy.[J].Talanta,2015,144:662-670.(IF4.035)
5.(10)JiaYu,XinleiLiang,ZhaokunWang,XinGuo,TieminSun,XingjieGuo.SeparationofFolinicAcidDiastereomersinCapillaryElectrophoresisUsingaNewCationicβ-CyclodextrinDerivative.[J].PLosOne,2015,10(3):1-10.(IF3.057)
6.LihongLin,MingyingDuan,GuangChen,XiaohongYou,ChanglinLiu,XingjieGuo.AnLC-MS/MSmethodfordeterminationofnovelfungicidepyraoxystrobininratplasmaandtissues:Toxicokineticsandtissuedistributionstudy.[J].Talanta,2015,136:183-189.(IF4.035)
7.JinxiaWei,ZhenJiang,ZhiCui,XingjieGuo.RapiddeterminationofeightoxoisoaporphinealkaloidsinRhizomaMenispermibytheoptimalhomogenateextractionfollowedbyUPLC-MS/MS.[J].AnalyticalandBioanalyticalChemistry,2015,407(18):5535-5540.(IF3.125)
8.XinleiLiang,LongshanZhao,MiaoduoDeng,LijieLiu,YongfuMa,XingjieGuo.SeparationofOfloxacinandItsSixRelatedSubstancesEnantiomersbyChiralLigand-ExchangeChromatography.[J].Chirality,2015,27(11):843-849.(IF2.025)
9.YanCui,ZhenJiang,JiayiSun,JiaYu,MinghuaLi,MingjieLi,MingxiaLiu,XingjieGuo.Enantiomericpuritydeterminationof(L)-aminoacidswithpre-columnderivatizationandchiralstationaryphase:Developmentandvalidationofthemethod.[J].FoodChemistry,2014,158:401-407.(IF4.052)
10.LihongLin,WeiYu,YananPang,ChangsongSun,QingheMeng,XiaoleiLi,XingjieGuo.ValidationofanLC-MS/MSmethodforthequantitativedeterminationofanovelfungicide:pyraoxystrobininratplasmaanditsapplicationtoatoxicokineticsstudy.[J].AnalyticalandBioanalyticalChemistry,2014,406(22):5521-5526.IF3.125)