个人简介
韩飞,男,博士,副研究员,硕士生导师。2003年毕业于沈阳药科大学,获药学(日语)学士学位;2005-2008年于沈阳药科大学药剂系硕博连读,获药剂学博士学位;毕业后于沈阳药大药业有限责任公司工作,曾任公司研发总监兼生产总监。2012年,于沈阳药科大学药学院分析测试中心任教;2016年,被直聘为沈阳药科大学副研究员,主要研究方向为傅立叶变换离子回旋共振质谱法和质谱成像技术在药学研究领域的应用。作为课题负责人主持了国家自然科学基金面上项目1项,辽宁省教育厅一般项目1项,教育部新教师博士点基金1项。另外,作为项目骨干成员承担国家自然科学基金青年基金项目1项。目前已在Talanta,IntJ.Pharm.,RSCAdvances,Anal.Bioanal.Chem.,J.Chromatogr.B.等期刊发表SCI论文30余篇。
研究领域
研究方向一:质谱成像技术在药学研究领域的应用
研究方向二:超高分辨质谱傅立叶变换离子回旋共振质谱在药学研究领域的应用
研究方向三:新型MALDI基质的开发及应用
近期论文
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1.FeiHan,RanYin,XinChe,JingYuan,YananCui,HeYin,SanmingLi*.Nanostructuredlipidcarriers(NLC)basedtopicalgelofflurbiprofen:Design,characterizationandinvivoevaluation.InternationalJournalofPharmaceutics.439:349–357,2012.(IF=3.994)
2.FeiHan,YantingLi,LiMa,TianfengLiu,YawenWu,RuiXu,AihuaSong,RanYin.ArapidandsensitiveUHPLC-FT-ICRMS/MSmethodforidentificationofchemicalconstituentsinRhodiolacrenulataextract,ratplasmaandratbrainafteroraladministration.Talanta,2016,160,183-193.(IF=4.035)
3.FeiHan*,TianfengLiu,RanYin,XiaoshuZhang,LiMa,RuiXuandYawenWu.UHPLC-FT-ICR-MScombinedwithserumpharmacochemistryforbioactivecompoundsdiscoveryofZhi-Zi-Da-Huang-decoctionagainstalcohol-inducedhepatotoxicityinrats.RSCAdvances.2016,6,108917-108927.(IF=3.289)
4.FeiHan,Yan-tingLi,Xin-juanMao,Xiao-shuZhang,JiaoGuan,Ai-huaSong,YinRan.Metabolicprofileofsalidrosideinratsusinghigh-performanceliquidchromatographycombinedwithFouriertransformioncyclotronresonancemassspectrometry.AnalyticalandBioanalyticalChemistry.2016,408(7),1975-1981.(IF=3.125)
5.FeiHan,YangDong,ZhenSu,RanYin,AihuaSong,SanmingLi.Preparation,characteristicsandassessmentofanovelgelatin–chitosanspongescaffoldasskintissueengineeringmaterial.InternationalJournalofPharmaceutics.2014,476(1-2),124-133.(IF=3.65)
6.FeiHan,YantingLi,XinjuanMao,RuiXuandRanYin.CharacterizationofchemicalconstituentsinRhodiolaCrenulatebyhigh-performanceliquidchromatographycoupledwithFourier-transformioncyclotronresonancemassspectrometer.JournalofMassSpectrometry.2016,51,363-368.(IF=2.541)
7.FeiHan,YantingLi,XiaoshuZhang,AihuaSong,HeyunZhu,RanYin.ApilotstudyofdirectinfusionanalysisbyFT-ICRMSforrapiddifferentiationandauthenticationoftraditionalChineseherbalmedicines.InternationalJournalofMassSpectrometry.2016,403,62-67.(IF=2.183)
8.FeiHan,YantingLi,XiaoshuZhang,AihuaSong,HeyunZhu,RanYin.ComparativestudyofdirectinjectionanalysisandliquidchromatographymassspectrometryforidentificationofchemicalconstituentsinKudieziinjectionbyFT-ICRMSInternationalJournalofMassSpectrometry2016,405,32-38.(IF=2.183)
9.FeiHan,YangDong,AihuaSong,RanYin.Alginate/chitosanbasedbi-layercompositemembraneaspotentialsustained-releasewounddressingcontainingciprofloxacinhydrochloride.AppliedSurfaceScience.2014,311,626-634.(IF=2.711)
10.AihuaSong,XiaoshuZhang,YantingLi,XinjuanMao,FeiHan*.Effectofliquid-to-solidlipidratioonCharacterizationsofflurbiprofen-loadedsolidlipidnanoparticles(SLNs)andnanostructuredlipidcarriers(NLCs)fortransdermaladministration.DrugDevelopmentAndIndustrialPharmacy.2016,42(8),1308-1314.(IF=2.429)