个人简介
李三鸣,男,沈阳药科大学教授,博士生导师,辽宁省教学名师,山东省泰山学者,教育部化学课程教学指导委员会委员。兼任国家食品药品监督管理局新药评审专家、科技部重大新药创制评审专家、国家发改委项目论证专家、教育部专业设置和学位管理专家、国家中小企业创业基金评审专家、自然科学基金项目评审人、药学学报编委,人民卫生出版社《物理化学》,中国医药科技出版社《物理化学实验》主编。主持国家自然科学基金5项,科技部科技专项3项;获得各类新药证书20余项;获得省级科技进步二等奖1项、三等奖2项;在国内外学术期刊发表论文240余篇,其中SCI收载60余篇。主编和参编教材12部。主要从事药物新剂型及其释药机制的基础研究,同时进行新药研发工作。
研究领域
研究方向一:辅料功能性与辅料性质和结构关系的构建及其功能性评价方法学研究
研究方向二:药物新剂型及其释药机制的基础研究
近期论文
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1.BHu,WSun,BYang,HLi,LZhou,etal.ApplicationofSolventParametersforPredictingOrganogelFormation.,AapsPharmscitech.,2018(IF=2.666)
2.BHu,WWang,YWang,YYang,LXu,etal.Degradationofglutamate-basedorganogelsforbiodegradableimplants:Invitrostudyandinvivoobservation,MaterialsScienceandEngineeringC,2018(IF=5.080)
3.HLi,HLi,CWei,JKe,JLi,et.Biomimeticsynthesisandevaluationofhistidine-derivativetemplatedchiralmesoporoussilicaforimprovedoraldeliveryofthepoorlywater-solubledrug,nimodipine.EuropeanJournalofPharmaceuticalSciences,2018(IF=3.466)
4.HeranLi,JianxinWang,JialiangCong,etal.Biomimeticsynthesisofproline-derivativetemplatedmesoporoussilicaforincreasingthebraindistributionofdiazepamandimprovingthepharmacodynamicsofnimesulide,Drugdelivery,2017(IF=6.402)
5.BeibeiHu,YueYuan,YunYan,etal.Preparationandevaluationofanovelanticancerdrugdeliverycarrierfor5-Fluorouracilusingsyntheticbola-amphiphilebasedonlysineaspolarheads,MaterialsScienceandEngineeringC,2018(IF=5.080)
6.BaixueYang,ChenWei,YangYang,etal.Evaluationaboutwettability,waterabsorptionorswellingofexcipientsthroughvariousmethodsandthecorrelationbetweentheseparametersandtabletdisintegration,DrugDevelopmentandIndustrialPharmacy,2018(IF=1.883)
7.YibinYu,etal.Nanostructuredlipidcarrier-basedpHandtemperaturedual-responsivehydrogelcomposedofcarboxymethylchitosanandpoloxamerfordrugdelivery,InternationalJournalofBiologicalMacromolecules,2018(IF=3.909)
8.HongyuWang,YiweiSun,BaixueYang,etal.AssociationbetweenthephysicalstabilityofflurbiprofensuspensionandtheinteractionofHPMC/SDS,AsianJournalofPharmaceuticalSciences,2017(IF=4.56)
9.JinxuCao,BaixueYang,YumeiWang,etal.Polymerbrushhexadecyltrimethylammoniumbromide(CTAB)modifiedpoly(propylene-g-styrenesulphonicacid)fiber(ZB-1):CTAB/ZB-1asapromisingstrategyforimprovingthepoorlywater-solubledrugsdissolutionandphysicalstabilityofflurbiprofen,MaterialsScienceandEngineeringC,2017(IF=5.080)
10.MiaoZhang,BaixueYang,WeiLiu,etal.Influenceofhydroxypropylmethylcellulose,methylcellulose,gelatin,poloxamer407andpoloxamer188ontheformationandstabilityofsoybeanoil-in-wateremulsions,AsianJournalofPharmaceuticalSciences,2017(IF=4.56)
学术兼职
1.山东省泰山学者;
2.教育部化学课程教学指导委员会委员;
3.国家自然科学基金项目通讯评审人;