徐志爱 - 华东师范大学 - 化学与分子工程学院

个人简介

教育经历 2001年9月－2006年12月，中国科学院长春应用化学研究所，博士工作经历 2018年1月－至今：华东师范大学教授 2012年5月－2017.12：华东师范大学副教授 2009年6月－2012年4月：助教授，东北大学，日本 (Tohoku University, Japan)。 2007年6月－2009年5月：日本学术振兴会（JSPS）博士后研究员，东北大学，日本 (Tohoku University, Japan)

研究领域

生物大分子的组装及在生物分析中的应用荧光探针的合成和生物分析应用癌症和神经退行性疾病等相关分析检测与治疗

近期论文

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Y. Dang, L. Ruan, Y. Tian, Z. Xu,* and W. Zhang,* Nitric Oxide Prodrug Delivery and Release Monitoring Based on Galactose-Modified Multifunctional Nanoprobe. Anal. Chem. 2021, 93, 7625-7634. L. Lei, Z. Zou, J. Liu, Z. Xu,* Y. Fu, Y. Tian and W. Zhang* Multifunctional peptide-assembled micelles for simultaneously reducing amyloid-β and reactive oxygen species, Chemical Science, 2021, 2021, 12, 6449-6457. F. Zhou, J. Gao, Z. Xu, * T. Li, A. Gao, F. Sun, F. Wang, W. Wang, Y. Geng, F. Zhang, Z.P. Xu, H. Yu*. Overcoming immune resistance by sequential prodrug nanovesicles for promoting chemoimmunotherapy of cancer. Nano Today, 2021, 36, 101025. L. Lei, M. Li, S. Wu, Z. Xu, * P. Geng, Y. Tian, Y. Fu, and W. Zhang *, Non-invasive In-situ Ratiometric Imaging of Biometals Based on Self-Assembling Peptide Nanoribbon. Anal. Chem. 2020, 92, 5838-5845. Y. Lai, Y. Zhu, Z. Xu,* X. Hu, M. Saeed, H. Yu, X. Chen, J. Liu, W. Zhang*, Engineering Versatile Nanoparticles for Near-Infrared Light-Tunable Drug Release and Photothermal Degradation of Amyloid β. Adv. Funct. Mater. 2020, 30, 1908473. Yijing Dang, Fengyang Wang, Lingling Li, Yi Lai, Zhiai Xu, * Zhi Xiong, Ao Zhang, Yang Tian, Chunyong Ding,* and Wen Zhang* Activatable near-infrared fluorescent probe for methylglyoxal imaging in Alzheimer's disease mice. Chem. Commun. 2020, 56, 707-710. Y. Lai, Z. Xu,* X. Hu, L. Lei, L. Li, L. Dong, H. Yu,* W. Zhang*. Peptide Nanotube-Templated Biomineralization of Cu2-xS Nanoparticles for Combination Treatment of Metastatic Tumor. Small 2019, 1904397. L. Lei, R. Geng, Z. Xu,* Y. Dang, X. Hu, L. Li, P. Geng, Y. Tian, W. Zhang*. Glycopeptide Nanofiber Platform for Ab-Sialic Acid Interaction Analysis and Highly Sensitive Detection of Ab. Anal. Chem. 2019, 91, 8129-8136. R. Geng, D. Lu, Y. Lai, S. Wu, Z. Xu* and W. Zhang*, Peptide nanotube for carbon dioxide chemisorption with regeneration properties and water compatibility. Chem. Commun. 2019, 55, 3797-3800. L. Lei, Z. Xu*, X. Hu, Y. Lai, J. Xu, B. Hou, Y. Wang, H. Yu*, Y. Tian, W. Zhang*. Bioinspired Multivalent Peptide Nanotubes for Sialic Acid Targeting and Imaging-Guided Treatment of Metastatic Melanoma. Small 2019, 15(22), 1900157. F. Wang, S. Yu, Z. Xu, * L. Li, Y. Dang, X. Xu, Y. Luo, Z. Cheng, H. Yu, W. Zhang, A. Zhang, and C. Ding*. Acid-Promoted D-A-D Type Far-Red Fluorescent Probe with High Photostability for Lysosomal Nitric Oxide Imaging, Anal. Chem. 2018, 90 (13), 7953-7962. F. Lin, Y. Zhou, Q. Li, X. Zhou, Y. Shao,* B. Habermeyer, H. Wang, X. Shi, and Z. Xu,* Prototropically Allosteric Probe for Superbly Selective DNA Analysis, Anal. Chem. 2017, 89 (17), 9299–9306. C. Feng, F. Wang, Y. Dang, Z. Xu, * H. Yu, and W. Zhang. A Self-Assembled Ratiometric Polymeric Nanoprobe for Highly Selective Fluorescence Detection of Hydrogen Peroxide, Langmuir, 2017, 33, 3287–3295. Y. Hu, F. Lin, T. Wu, Y. Zhou, Q. Li, Y. Shao,* Z. Xu, * DNA Duplex Engineering for Enantioselective Fluorescent Sensor, Anal. Chem., 2017, 89, 2181-2185. L. Lu, C. Feng, J. Xu, F. Wang, H. Yu, Z. Xu, * W. Zhang, Hydrophobic-carbon-dot-based dual-emission micelle for ratiometric fluorescence biosensing and imaging of Cu2+ in liver cells, Biosensors and Bioelectronics, 2017, 92, 101-108. F. Wang, ? Q. Sun, ? B. Feng, Z. Xu, * J. Zhang, J. Xu, L. Lu, H. Yu, M. Wang, Y. Li and W. Zhang*, Polydopamine-Functionalized Graphene Oxide Loaded with Gold Nanostars and Doxorubicin for Combined Photothermal and Chemotherapy of Metastatic Breast Cancer, Adv. Healthc. Mater., 2016, 5, 2227–2236. J. Zhang, J. Liu, Y. Zhu, Z. Xu, * J. Xu, T. Wang, H. Yu and W. Zhang*, Photodynamic micelles for amyloid β degradation and aggregation inhibition, Chem. Commun., 2016, 52, 12044-12047. Y. Wang, L. Lu, H.Peng, J. Xu, F. Wang, R. Qi, Z. Xu* and W. Zhang*, Multi-doped carbon dots with ratiometric pH sensing properties for monitoring enzyme catalytic reactions. Chem. Commun., 2016, 52, 9247-9250. L. Zhu, J. Zhang, F. Wang, Y. Wang, L. Lu, C. Feng, Z. Xu*, W. Zhang*. Selective amyloid β oligomer assay based on abasic site-containing molecular beacon and enzyme-free amplification, Biosensors and Bioelectronics, 2016, 78, 206-212. Y. Wang, Q. Sun, L. Zhu, J. Zhang, F. Wang, L. Lu, H. Yu, Z. Xu* and W. Zhang*. Triplex molecular beacons for sensitive recognition of melamine based on abasic-site-containing DNA and fluorescent silver nanoclusters. Chem. Commun., 2015, 51, 7958-7961. B. Lin, D. Lu, Y. Fu, Q. Sun, K. Liu, Z. Xu* and W. Zhang*. Label-free Colorimetric Protein Assay and Logic Gates Design Based on the Self-assembly of Hemin-Graphene Hybrid Nanosheet. Langmuir, 2014, 30(8), 2144-251. Y. An, Y. Fu, D. Lu, Y. Wang, W. Bi, Z. Xu,* S. Dong, S. Zhang, C. Wang and W. Zhang*. A TiO2-Au–polymer hybrid system for the photoelectrochemical immunoassay of SirT1. J. Mater. Chem. B, 2014, 2, 1644-1652.