个人简介
学习简历:
1996.09-2000.06安徽师范大学应用化学专业获学士学位
2000.09-2003.06苏州大学无机化学专业获硕士学位
2003.09-2006.06苏州大学有机化学专业获博士学位
工作简历:
2006.07-2009.11南方医科大学药物化学教研室讲师
2009.12-2014.11南方医科大学合成药物化学课题组副教授
2013.04-2014.04新加坡科技研究局材料工程研究院访问学者
2014.12-2015.12南方医科大学合成药物化学课题组教授
2016.01-至今南方医科大学无机药物化学课题组教授学科主任
近5年获得的科研课题：
(1)主持国家自然科学基金面上项目，同源细胞膜包裹P-DNA@MOF荧光/MRI双模态探针的构建及其癌症靶向诊断功能研究，项目编号：21874064，起止时间：2019年1月-2022年12月。
(2)主持广东省自然科学基金项目，具有水稳定性的纳米金属有机骨架的构建及其多种埃博拉病毒核酸分子保守序列同步识别功能研究，项目编号：2018A030313456，起止时间：2018年5月-2021年4月。
(3)主持广州市科技计划项目，荧光/MRI双模态探针CCMs+P-DNA@MOF的构建及其精准靶向癌症早期诊疗功能研究；起止时间：2019年4月-2022年3月。
(4)主持广东省自然科学基金自由申请项目，“具有空气水稳定性的两性金属有机骨架的合成及其载药功能研究”，项目编号：2015A030313284，起止时间：2015年8月-2018年8月。
(5)主持广东省公益研究与能力建设专项资金项目“新型生物医用材料金属有机骨架的构建及载药功能研究”，项目编号：2015A010105016，起止时间：2015年1月-2017年12月。
近5年获得的发明专利:
(1)Chen,Jin-Xiang;Xie,Bao-Ping;Qiu,Gui-Hua;Hu,Pei-Pei;Liang,Zhen;Liang,Ye-Mei;Sun,Bin;Bai,Li-Ping;Jiang,Zhi-Hong;Crystallinecopper-basedcoordinationpolymersandtheiruse.澳洲发明专利，专利号：AU:2017100590
(2)Chen,Jin-Xiang;Sun,Bin;Xie,Bao-Ping;Jiang,Zhi-Hong;Bai,Li-Ping;Crystallinelanthanum-carboxylatecoordinationpolymersandtheiruse.澳洲发明专利，AU:2017100565
(3)Chen,Jin-Xiang;Sun,Bin;Zhao,Hai-Qing;Xie,Bao-Ping;Bai,Li-Ping;Jiang,Zhi-Hong;Zwitterioniczinc(II)carboxylatecompoundsandtheiruse.澳洲发明专利。专利号：AU:2016101528
(4)Chen,Jin-Xiang;Pang,Jian-Xin;Liu,Shu-Wen;Bai,Li.Ping;Jiang,Zhi-Hong;Crystallinecontrastagentformagneticresonanceimaging,kitandcompositioncomprisingitandtheiruse.澳洲发明专利，专利号：AU:2016101702
(5)Chen,Jin-Xiang;Sun,Bin;Zhao,Hai-Qing;Xie,Bao-Ping;Bai,Li-Ping;Jiang,Zhi-Hong;Zwitterioniczinc(II)carboxylatecompoundsandtheiruse.美国发明专利，专利号：US10,023,594B2
(6)Chen,Jin-Xiang;Sun,Bin;Xie,Bao-Ping;Jiang,Zhi-Hong;Bai,Li-Ping;Crystallinelanthanum-carboxylatecoordinationpolymersandtheiruse.美国发明专利，专利号：US10.260.114B2。
(7)陈金香，杨水平，陈文华，一种两性羧酸镧金属有机骨架及其合成方法和应用，申请号：201510952885.X，授权日：2018年12月4日，专利号：ZL201510952885.X
(8)陈金香，覃亮，陈文华，刘叔文，庞建新，一种基于锰的两性羧酸金属配位聚合物及其制备方法，中国发明专利，专利号：ZL201610404049.2
(9)陈金香，覃亮，陈文华，刘叔文，庞建新，一种基于钆的两性羧酸金属配位聚合物及其制备方法，中国发明专利，专利号：ZL201610403497.0
(10)陈金香，覃亮，陈文华，刘叔文，谢宝平，孙斌，一种两性羧酸四核铜金属配位聚合物及其制备方法，专利号：ZL201610403491.3
(11)陈金香，覃亮，陈文华，刘叔文，谢宝平，孙斌，一种两性羧酸双核铜金属配位聚合物及其制备方法，中国发明专利，专利号：ZL201610404106.7
(12)陈金香，覃亮，陈文华，刘叔文，谢宝平，孙斌，一种两性羧酸六核铜金属配位聚合物及其制备方法，中国发明专利，专利号：ZL201610404108.6
近期论文
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近5年以第一作者或通讯作者发表的SCI论文:
(1)Shi-XinLin,Wei-LunPan,Ru-JieNiu,YanLiu,Jin-XiangChen,*Wen-HuaZhang,*Jian-PingLang*andDavidJ.Young,EffectiveloadingofcisplatinintoananoscaleUiO-66metal–organicframeworkwithpreformeddefects,DaltonTrans.,2019,48,5308–5314.
(2)Shao-LanCai,Zi-ChuanYang,Ke-YangWu,ChengFan,Ling-YanZhai,Nai-HanHuang,Rong-TianLi,Wen-JunDuan*andJin-XiangChen*,ExperimentalandcomputationalinvestigationofaDNA-shielded3Dmetal-organicframeworkforthepromptdualsensingofAg+andS2−.RSCadv.2019,9,15424‒15430.
(3)Nai-HanHuang,Rong-TianLi,ChengFan,Ke-YangWu,ZheZhang,Jin-XiangChen*RapidsequentialdetectionofHg2+andbiothiolsbyaprobeDNA-MOFhybridsensorysystem,J.Inorg.Biochem.,2019,197,110690.
(4)Ke-YangWu,LiangQin,ChengFan,Shao-LanCai,BinSun,Bao-PingXie,Xiao-YanTang*andJin-XiangChen*SequentialandRecyclableSensingofFe3+andAscorbicAcidBasedonaWater-stableGreen-emittingTerbium(III)Metal−OrganicFramework,DaltonTrans.,2019,48,8911-8919.
(5)Bao-PingXie,Gui-HuaQiu,BinSun,Zi-FengYang,Wen-HuaZhang,*Jin-XiangChen,*Zhi-HongJiang*SynchronoussensingofthreeconservedsequencesofZikavirusbyaDNAs@MOFhybrid:Experimentalandmolecularsimulationstudies,Inorg.Chem.Frontier.2019,6,148-152.
(6)Ling-YanZhai#,Min-XiangLi#,Wei-LunPan,YunChen,Min-MinLi,Jian-XinPang,LeiZheng*,Jin-XiangChen*,Wen-JunDuan*,InSituDetectionofPlasmaExosomalMicroRNA-1246forBreastCancerDiagnosticsbyaAuNanoflareProbe,ACSAppl.Mater.Inter.2018,10,39478-39486.
(7)Xiang-MingHu#,Rong-TianLi#,Miao-MiaoZhang,Ke-YangWu,Huan-HuanLi,Nai-HanHuang,BinSun*,Jin-XiangChen*Phenanthroline-linkedberberinedimerandfluorophore-taggedDNAconjugatefortheselectivedetectionofmicroRNA-185:experimentalandmoleculardockingstudies,Anal.Chim.Acta,2019,1051,153-159.
(8)Pei-PeiHu,NingLiu,Ke-YangWu,Ling-YanZhai,Bao-PingXie,BinSun,Wen-JunDuan,Wen-HuaZhang,*andJin-XiangChen*SuccessiveandSpecificDetectionofHg2+andI−byaDNA@MOFBiosensor:ExperimentalandSimulationStudies,Inorg.Chem.2018,57(14),8382-8389.
(9)Bao-PingXie#,Gui-HuaQiu#,Pei-PeiHu,ZhenLiang,Ye-MeiLiang,BinSun,Li-PingBai,Zhi-HongJiang,Jin-XiangChen∗SimultaneousdetectionofDengueandZikavirusRNAsequenceswithathree-dimensionalCu-basedzwitterionicmetal−organicframework,comparisonofsingleandsynchronousfluorescenceanalysis,Sensor.Actuat.B-Chem.2018,254C,1133-1140.
(10)BinSun1,ZhenLiang1,Bao-PingXie,Rong-TianLi,Lin-ZeLi,Zhi-HongJiang,Li-PingBai,Jin-XiangChen∗,Fluorescencesensingplatformbasedonruthenium(II)complexesashigh3S(sensitivity,specificity,speed)and“on-off-on”sensorsforthemiR-185detection,Talanta,2018,179,658-667.
(11)Gui-HuaQiu,Zi-HuaWeng,Pei-PeiHu,Wen-JunDuan,Bao-PingXie,BinSun,Xiao-YanTang,Jin-XiangChen*,SynchronousdetectionofebolavirusconservedRNAsequencesandebolavirus-encodedmiRNA-likefragmentbasedonazwitterioniccopper(II)metal–organicframework,Talanta,2018,180,396-402.
(12)LiangQin,#Zi-YanSun,#KaiCheng,Shu-WenLiu,Jian-XinPang,Li-MingXia,Wen-HuaChen,*ZhenCheng,*andJin-XiangChen*Zwitterionicmanganesandgadoliniummetal–organicframeworksasefficientmagneticresonancecontrastagentsforinvivoimaging,ACSAppl.Mater.Inter.2017,9(47),41378-41386.
(13)Shui-PingYang,WeiZhao,Pei-PeiHu,Ke-YangWu,Zhi-HongJiang,Li-PingBai,Min-MinLi,andJin-XiangChen*,Lanthanum-basedmetal−organicframeworksforspecificdetectionofSudanvirusRNAconservativesequencesdowntosingle-basemismatch,Inorg.Chem.2017,56,14880-14887.
(14)Gui-HuaQiua,1Wan-ZhenLu1,Pei-PeiHu,Zhi-HongJiang,Li-PingBai,Tao-RuiWang,Min-MinLi,*Jin-XiangChen,*Ametal-organicframeworkbasedPCR-freebiosensorforthedetectionofgastriccancerassociatedmicroRNAs,J.Inorg.Biochem.2017,177,138-142.
(15)BinSu1,Hai-QingZha1,Bao-PingXie,Li-PingBai,Zhi-HongJiang,Jin-XiangChen,*Sequence-specificfluorometricrecognitionofHIV-1ds-DNAbyusingzwitterioniczinc(II)-carboxylatepolymers,J.Inorg.Biochem.2017,176,17-23.
(16)Hai-QingZhao1,Gui-HuaQiu1,ZhenLiang,Min-MinLi,BinSun,LiangQin,Shui-PingYang,Wen-HuaChen,Jin-XiangChen*,AZinc(II)-basedtwo-dimensionalMOFforsensitiveandselectivesensingofHIV-1ds-DNAsequences,Anal.Chim.Acta,2016,922,55-63.
(17)Hai-QingZhao,‡Shui-PingYang,‡Ni-NiDing,LiangQin,Gui-HuaQiu,Jin-XiangChen,*Wen-HuaZhang,*Wen-HuaChen*andT.S.AndyHor*Azwitterionic1D/2Dpolymerco-crystalanditspolymorphicsub-components:ahighlyselectivesensingplatformforHIVds-DNAsequences,DaltonTrans.,2016,45,5092–5100.
(18)LiangQin,Li-XianLin,Zhi-PingFang,Shui-PingYang,Gui-HuaQiu,Jin-XiangChen*andWen-HuaChen*Awater-stablemetal-organicframeworkofazwitterioniccarboxylatewithdysprosium:asensingplatformforEbolavirusRNAsequences,Chem.Commu.2016,52,132-135.
(19)Shui-PingYang,Shao-RuiChen,Shu-WenLiu,Xiao-YanTang,LiangQin,Gui-HuaQiu,Jin-XiangChen,*Wen-HuaChen,*Platformsformedfroma3DCu-basedzwitterionicmetal−organicframeworkandprobess-DNA:selectivefluorescentbiosensorsforHIV-1ds-DNAandSudanvirusRNAsequences,Anal.Chem.2015,87,12206-12214.
(20)MingChen,Xiao-YanTang,Shui-PingYang,Huan-HuanLi,Hai-QingZhao,Zhi-HongJiang,Jin-XiangChen,*Wen-HuaChen,*Fivewater-solublezwitterioniccopper(II)-carboxylatepolymers:roleofdipyridylcoligandsinenhancingtheDNA-binding,cleavingandanticanceractivities,DaltonTrans.2015,44,13369-13377.
(21)MingChen,Xiao-YanTang,Ming-ZhenChen,Jin-XiangChen*,Wen-HuaChen*,LanthanidebasedPolymerswithChargedLigandBackbones:Triple-strandedChainStructuresandtheirDNACleavageStudies,Aust.JChem.2015,48,493-499.
(22)Zi-XuanZhang,Ni-NiDing,Wen-HuaZhang*,Chen,Jin-Xiang*,Young,DavidJ.*,AndyHor,T.S.*Stitching2DPolymericLayersintoFlexibleInterpenetratedMetal–OrganicFrameworkswithinSingleCrystals,Angew.Chem.Int.Ed.2014,53,4628-4632.
(23)Jin-XiangChen,*MingChen,Ni-NiDing,Wen-HuaChen,Wen-HuaZhang,*AndyHor,T.S.*;Young,DavidJ.*TransmetalationofaDodecahedralNa9Aggregate-basedPolymer:aFacileRoutetoWaterStableCu(II)CoordinationNetworks,Inorg.Chem.2014,53,7446-7545.
(24)Jin-XiangChen*,Hai-QingZhao,Huan-HuanLi,Sheng-LiHuang,Ni-NiDing,Wen-HuaChen,Young,DavidJ.;Wen-HuaZhang*,AndyHor,T.S*.BentTritopicCarboxylatesforCoordinationNetworks:CluestotheOriginofSelf-penetration,CrystEngComm.2014,16,7722-7730.
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