张剑波 - 华东师范大学 - 化学与分子工程学院

个人简介

教育经历 1993年毕业于复旦大学药学院，获理学学士学位。随后进入中科院上海有机化学研究所攻读研究生学位，于1996年、1999 年获理学硕士与博士学位。2000年至2003 年，在美国进行博士后研究工作经历 2003年11月至今，任华东师范大学副教授，硕士生导师

研究领域

本课题组以糖类化合物的研究为中心，致力于发展绿色、高效的糖苷化方法和合成策略，并以之为基础研究合成含有糖结构单元的生物活性分子，探索新型抗肿瘤和抗病毒药物。 1. 化学生物学（糖化学和糖生物学） 2. 绿色有机合成 3. 糖类药物 4. 生物表面活性剂

近期论文

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Youxian Dong, Hong Guo, Dina Ma, Nan Jiang, Zekun Ding, Jianbo Zhang* Copper-Catalyzed Direct Stereoselective Synthesis of 2-deoxyglycosides Synlett 2020, 31, 1087-1093 Mei Y, Dong Y, Li J, et al. and Zhang J. FeCl3/C as an efficient catalyst for Ferrier rearrangement of 3,4,6-tri-O-Benzyl-D-glucal. J. Carbohydr. Chem.,2020, 39, 232-249. Jiang N, Dong Y, Sun G, et al. and Zhang J. Core-Shell Fe3O4@Carbon@SO3H: A Powerful Recyclable Catalyst for the Synthesis of α-2-Deoxygalactosides. ChemistrySelect, 2020, 5, 1592-1596. Dong Y, Ding Z, Guo H, et al. and Zhang J. A Highly Efficient Magnetic Iron(III) Nanocatalyst for Ferrier Rearrangements. Synlett, 2019, 30, 1419-1426.被Synfacts杂志Highlight报道 (Synfacts 2019, 15(10), 1165) Guo H, Si W, Li J, et al. and Zhang J. An Unexpected FeCl3/C-Catalyzed β-Stereoselective Glycosylation in the Presence of the C(2)-Benzyl Group. Synthesis 2019, 51, 2984-3000. Yang G, Luo X, Guo H, et al. and Zhang J. α-Selective Synthesis of 2-Deoxy-Glycosides and Disaccharides. J. Carbohydr. Chem., 2018, 37, 128-152. Ding Z, Luo X, Ma Y, et al. and Zhang J. Eco-friendly synthesis of 5-hydroxymethylfurfural (HMF) and its application to the Ferrier-rearrangement reaction J. Carbohydr. Chem., 2018, 37, 81-93. Sun G, Wu Y, Liu A, et al. and Zhang J. Substoichiometric FeCl3 Activation of Propargyl Glycosides for the Synthesis of Disaccharides and Glycoconjugates. Synlett, 2018, 29, 668-672. Liu N, Tian X, Ding Z, et al. and Zhang J. Synthesis of aryl α-O-L-rhamnopyranoside by two-step reaction in one pot. J. Carbohydr. Chem., 2017, 36, 220-234 Qiu S, Sun G, Ding Z, et al. and Zhang J. Ferric Chloride: An Eco-friendly Catalyst for the Stereoselective Synthesis of 2-Deoxy Aryl-O-Rhamnosides. Synlett 2017, 28, 2024-2029. Sun G, Qiu S, Ding Z, et al. and Zhang J. Magnetic Core-Shell Fe3O4@C-SO3H as an Efficient and Renewable 'Green Catalyst' for the Synthesis of O-2,3-Unsaturated Glycopyranosides. Synlett2016, 27, 347-352. Chen H, Luo X, Qiu S, et al. and Zhang J. TMSOTf mediated stereoselective synthesis of α-C-glycosides from unactivated aryl acetylenes. Glycoconj. J., 2017, 34, 13-20. Zhang W, Luo X, Wang Z, et al. and Zhang J. One-pot synthesis of β-2,6-dideoxyglycosides via glycosyl iodide intermediates. J. Carbohydr. Chem., 2016, 35, 315-325. Qiu S, Wan Z, Sun G, et al. and Zhang J. A Facile and Direct Glycosidation Method for the Synthesis of 2‐Deoxy α‐Rhamnosides Catalyzed by Ferric Chloride. ChemistrySelect 2016, 1, 4840-4844. Chen H, Xian T, Zhang W, et al. and Zhang J. An efficient method for the synthesis of pyranoid glycals. Carbohydr Res., 2016, 431, 42-46. Zhou J, Chen H, et al. and Zhang J. FeCl3·6H2O/C: An Efficient and Recyclable Catalyst for the Synthesis of 2,3-Unsaturated O-and S-Glycosides. J. Carbohydr. Chem., 2014, 33, 313-325. Zhang J, Zhang B, Zhou J, et al. A Facile H2SO4-SiO2-Catalyzed Ferrier Rearrangement of 3,4,6-Tri-O-benzyl-D-glucal. J. Carbohydr. Chem., 2014, 32, 380-391. Yang G, Wang Q, Luo X, et al. and Zhang J. Facile TMSOTf-catalyzed preparation of 2-deoxy α-O-aryl-D-glycosides from glycosyl acetates. Glycoconj J., 2012, 29, 453-456. Zhang J, Jie F, Si W, et al. and Zhang J. A highly efficient deprotection of the 2,2,2-trichloroethyl group at the anomeric oxygen of carbohydrates. Carbohydr Res.,2011, 346, 2290-2293. Zhou J, Zhang B, Yang G, et al. and Zhang J. A Facile H2SO4/4 ? Molecular Sieves Catalyzed Synthesis of 2,3-Unsaturated O-Glycosides via Ferrier-Type Rearrangement. Synlett2010, 6, 893–896.

学术兼职

国家食品药品监督管理局新药审评专家中国生物化学与分子生物学会分子生物技术专业委员会中国生物工程学会糖工程专业委员会委员上海药学会海洋药物专业委员会委员