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Fluorogenic Peptide Sensor Array Derived from Angiotensin-Converting Enzyme Classifies Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern W.-T. Dou‡‡†, P.-H. Tong†, M. Xing†, J.-J. Liu, X.-L. Hu, T. D. James*, D.-M. Zhou*, X.-P. He* J. Am. Chem. Soc. 2024, 146, 21017-21024. DOI 10.1021/jacs.4c06172
Isoindoline-based fluorogenic probes bearing a self-immolative linker for the sensitive and selective detection of O-GlcNAcase activity Yuan-Hao Wu‡, Guan-Jun Wang‡, Chen Guo‡, Pei-Pei Wang, Jun-Yi Wang, Xi-Le Hu*, Yi Zang*, Tony D. James*, Jia Li*, Xiao-Peng He* Chem. Commun. 2024 DOI 10.1039/d4cc02845g
An esterase-activated diketopyrrolopyrrole-based theranostic prodrug for precise pyroptosis and synergistic chemo photodynamic therapy of pancreatic cancer Xixin Gu‡, Kaini Yang‡, Sifan Li, Ju Mei, Xiao-Peng He*, Wei Chen*, Jianli Hua* Mater. Chem. Front. 2024, 8, 1993-2001. DOI 10.1039/D4QM00052H
Theranostic Fluorescent Probes Amit Sharma*, Peter Verwilst, Mingle Li, Dandan Ma, Nem Singh, Jiyoung Yoo, Yujin Kim, Ying Yang, Jing-Hui Zhu, Haiqiao Huang, Xi-Le Hu, Xiao-Peng He*, Lintao Zeng*, Tony D. James*, Xiaojun Peng*, Jonathan L. Sessler*, and Jong Seung Kim* Chem. Rev. 2024, 124, 2699–2804. DOI 10.1021/acs.chemrev.3c00778
Protein-encapsulated long-wavelength fluorescent probe hybrid for imaging lipid droplets in living cells and mice with non-alcoholic fatty liver Han-Min Wang, Yan-Chen Li, Lu-Lu Sun, Ming-Ye Tang, Jia Liu, Jiahao Cai, Lei Dong*, Jia Li*, Yi Zang*, Han Hai-Hao*, Xiao-Peng He* Chin. Chem. Lett. 2024 DOI 10.1016/j.cclet.2024.109603
The development of logic gate-based fluorescent probes that respond to intracellular hydrogen peroxide and pH in tandem Hai-Hao Han, Meng-Jiao Liu, Weijian Zhang, Lu-Lu Sun, Xiuhua Ma, Hongjin Qiao, Shasha Sun, Jianming Yang, Xianzhi Chai*, Zhenyong Wu*, Xiao-Peng He* Talanta 2024, 270, 125526. DOI 10.1016/j.talanta.2023.125526
Selective FRET nano probe based on carbon dots and naphthalimide–isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury Yueci Wu†, Lu-Lu Sun†, Hai-Hao Han*, Xiao-Peng He*, Weiguo Cao* and Tony D. James* Chem. Sci. 2024, 15, 757-764. DOI 10.1039/d3sc05010f
Targeted Near-Infrared Fluorescence Imaging of Liver Cancer using Dual-Peptide-Functionalized Albumin Particles Wei-Tao Dou, Chen Guo, Ling Zhu, Peng Qiu, Weijuan Kan, Yu-Fei Pan, Yi Zang, Li-Wei Dong, Jia Li*, Ye-Xiong Tan*, Hong-Yang Wang*, and Xiao-Peng He* Chem. Biomed. Imaging 2024, 1, 47–55. DOI 10.1021/cbmi.3c00078
Editorial: Frontiers in Chemistry: rising stars 2022 Carlos D. S. Brites*‡, Daniele Contini*‡, Xiao-Peng He*‡, Tianqing Liu*‡, Basem Moosa*‡, Marianna Pannico*‡, Mohamed Nageeb Rashed*‡, Yunping Qiu*‡ and Clemens Zwergel*‡ Front. Chem. 2023, 11, 1334117. DOI 10.3389/fchem.2023.1334117
Orthogonally Engineered Albumin with Attenuated Macrophage Phagocytosis for the Targeted Visualization and Phototherapy of Liver Cancer Wei-Tao Dou, Peng Qiu, Yuanyuan Shi, Ling Zhu, Chen Guo, Na Li, Yi Zang, Tingting Liu, Suwen Zhao, Yufei Pan, Liwei Dong, Jonathan L. Sessler*, Yexiong Tan*, Jia Li*, Hongyang Wang*, He Tian, Xiao-Peng He* J. Am. Chem. Soc. 2023, 145, 17377–17388. DOI 10.1021/jacs.3c05052
Repurposing a long-wavelength fluorescent boronate probe for the detection of reactive oxygen species (ROS) in bacteria Kai-Cheng Yan, Naing Thet, Rachel A. Heylen, Adam C. Sedgwick*, Tony D. James*, A. Toby A. Jenkins*, Xiao-Peng He* Sens. Diagn. 2023, 2, 1181-1185. DOI 10.1039/D3SD00049D
Metal-organic framework (MOF) hybridized gold nanoparticles as a bifunctional nanozyme for glucose sensing Pei-Hong Tong, Jing-Jing Wang, Xi-Le Hu, Tony D. James*, Xiao-Peng He* Chem. Sci. 2023, 14, 7762-7769. DOI 10.1039/D3SC02598E
Rapid identification of molecular subtyping of breast cancer cell lines using a multi-channel sensor array Yuyao Jin‡, Yuanjie Sun‡, Nan Du, Wei-Tao Dou, Ying Tan Xiao-Peng He, Naihan Xu*, Chunyan Tan* Sens. Diagn. 2023, 2, 837-841. DOI 10.1039/D3SD00094J
A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species Kai-Cheng Yan, Jordan E. Gardiner, Adam C. Sedgwick, Naing Thet, Rachel A. Heylen, Tony D. James*, A. Toby A. Jenkins*, Xiao-Peng He* Chem. Commun. 2023, 59, 8278-8281. DOI 10.1039/D3CC00462G
Ratiometric sensing of β-galactosidase based on excited-state intramolecular proton transfer (ESIPT) and solid-state luminescence enhancement† He Tian, Jr., Wei Lin, Xi-Le Hu, Jing-Bo Wang, Min-Yu Zhang, Yi Zang, Xin-Yan Wu, Jia Li*, Tony D. James*, Xiao-Peng He* Org. Chem. Front. 2023, 10, 2913-2917. DOI 10.1039/d3qo00605k
Human serum albumin-based supramolecular host–guest boronate probe for enhanced peroxynitrite sensing He Tian Jr.‡, Chen Guo‡, Xi-Le Hu, Jing-Bo Wang, Yi Zang, Tony D. James*, Jia Li*, Xiao-Peng He* Org. Biomol. Chem. 2023, 21, 4661–4666. DOI 10.1039/d3ob00637a
Phenotyping of Methicillin-Resistant Staphylococcus aureus Using a Ratiometric Sensor Array Xi-Le Hu‡, Hui-Qi Gan‡, Zhao-Yang Qin, Qian Liu, Min Li*, Daijie Chen*, Jonathan L. Sessler*, He Tian, Xiao-Peng He* J. Am. Chem. Soc. 2023, 145, 8917-8926. DOI 10.1021/jacs.2c12798
Iodine substitution compromises the aggregation-induced emission (AIE) property and enhances the biothiol sensitivity of quinoline–malononitrile-based fluorescent probes Guo-Biao Zhu, Jie Gao, Min-Yu Zhang, Liu He, Hai-Hao Han, Yi Zang*, Jia Li*, Xiao-Peng He* Dyes Pigments 2023, 215, 11246. DOI 10.1016/j.dyepig.2023.111246
Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore Yueci Wu‡, Hai-Hao Han‡, Liu He, Li Li, Yi Zang, Jia Li*, Xiao-Peng He*, Yaping Ding*, Weiguo Cao* and Tony D. James* Chem. Commun. 2023, 59, 5051-5054. DOI 10.1039/d2cc06425a
A Highly Sensitive and Selective Near-Infrared Fluorescent Probe for Imaging Peroxynitrite in Living Cells and Drug-Induced Liver Injury Mice Xianzhi Chai, Bohan Li, Chi Chen, Weijian Zhang, Lulu Sun, Hai-Hao Han*, Yafei Zhang, Shasha Sun*, Jianming Yang, Junji Zhang*, Xiao-Peng He* Anal. Chem. 2023, 95, 5747–5753. DOI 10.1021/acs.analchem.3c00007
The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy Hai-Hao Han, Han-Min Wang, Paramesh Jangili, Mingle Li, Luling Wu*, Yi Zang, Adam C. Sedgwick*, Jia Li*, Xiao-Peng He*, Tony D. James* and Jong Seung Kim* Chem. Soc. Rev. 2023, 52, 879-920. DOI 10.1039/D2CS00673A
Targeted photothermal release of antibiotics by a graphene nanoribbon-based supramolecular glycomaterial Ying Shang‡, Sheng Zhang‡, Hui-Qi Gan‡, Kai-Cheng Yan, Fu-gui Xu, Yi-yong Mai, Dai-jie Chen, Xi-Le Hu*, Lei Zou*, Tony D. James* and Xiao-Peng He* Chem. Commun. 2023, 59, 1094-1097. DOI 10.1039/D2CC05879K
Fluorescent probes for the detection of chemical warfare agents Wen-Qi Meng‡*, Adam C. Sedgwick‡, Ming-xue Sun, Kai Xiao*, Xiao-Peng He*, Eric V. Anslyn*, Tony D. James* and Juyoung Yoon* Chem. Soc. Rev. 2023, 52, 601-662. DOI 10.1039/D2CS00650B
TCF-based fluorescent probe for monitoring superoxide anion produced in bacteria under chloramphenicol-and heat-induced stress Kai-Cheng Yan, Bethany L. Patenall, Jordan E. Gardiner, Rachel A. Heylen, Naing Thet, Xiao-Peng He, Adam C. Sedgwick*, Tony D. James*, A Toby A. Jenkins* Chem. Commun. 2022, 58, 13103-13106. DOI 10.1039/D2CC04662H
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues Chen-Jian Zhong, Xi-Le Hu, Xiao-Lan Yang, Hui-Qi Gan, Kai-Cheng Yan, Fu-Ting Shu, Pei Wei, Teng Gong, Peng-Fei Luo, Tony D. James, Zhao-Hong Chen*, Yong-Jun Zheng*, Xiao-Peng He*, and Zhao-Fan Xia* ACS Appl. Mater. Interfaces 2022, 14, 39808–39818. DOI 10.1021/acsami.2c10115
Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy Fang-Zhou Xu‡, Ling Zhu‡, Hai-Hao Han‡, Jian-Wei Zou*, Yi Zang, Jia Li*, Tony D. James*, Xiao-Peng He*, Cheng-Yun Wang* Chem. Sci. 2022, 13, 9373-9380. DOI 10.1039/D2SC00889K
Fluorescent probes and functional materials for biomedical applications Xi-Le Hu, Hui-Qi Gan, Fan-De Meng, Hai-Hao Han, De-Tai Shi, Shu Zhang*, Lei Zou*, Xiao-Peng He*, Tony D. James* Front. Chem. Sci. Eng. 2022, 16, 1425–1437. DOI 10.1007/s11705-022-2163-1
Fluorescence Analysis of Circulating Exosomes for Breast Cancer Diagnosis Using a Sensor Array and Deep Learning Yuyao Jin, Nan Du, Yuanfang Huang, Wanxiang Shen, Ying Tan, Yu Zong Chen, Wei-Tao Dou, Xiao-Peng He, Zijian Yang*, Naihan Xu*, and Chunyan Tan* ACS Sens. 2022, 7, 1524–1532. DOI 10.1021/acssensors.2c00259
Fluorescence evidence of annexin A6 translocation across membrane in model matrix vesicles during apatite formation Yubo Wang, Liliana Weremiejczyk, Agnieszka Strzelecka-Kiliszek, Ofelia Maniti, Ekeveliny Amabile Veschi, Mayte Bolean, Ana Paula Ramos, Layth Ben Trad, David Magne, Joanna Bandorowicz-Pikula, Slawomir Pikula, Jose Luis Millán, Massimo Bottini, Peter Goekjian, Pietro Ciancaglini, René Buchet, Wei Tao Dou, He Tian, Saïda Mebarek, Xiao P. He, Thierry Granjon* J. Extracell. Bio. 2022, 1, e38. DOI doi.org/10.1002/jex2.38
Tuning the Solid- and Solution-State Fluorescence of the Iron-Chelator Deferasirox Xi-Le Hu†, Adam C. Sedgwick†*, Daniel N. Mangel†, Ying Shang, Axel Steinbrueck, Kai-Cheng Yan, Ling Zhu, Dylan W. Snelson, Sajal Sen, Calvin V. Chau, Gabriel Juarez, Vincent M. Lynch, Xiao-Peng He*, Jonathan L. Sessler* J. Am. Chem. Soc. 2022, 144, 7382–7390. DOI 10.1021/jacs.2c01155
A homogeneous high-throughput array for the detection and discrimination of influenza A viruses Wei-Tao Dou†, Xiang Wang†, Tingting Liu, Suwen Zhao, Jiao-Jiao Liu, Yao Yan, Jun Li, Chi-Yu Zhang, Adam C Sedgwick, He Tian, Jonathan L Sessler*, Dong-Ming Zhou*, Xiao-Peng He* Chem 2022, 8, 1750-1761. DOI 10.1016/j.chempr.2022.03.012
Targeted delivery of maytansine to liver cancer cells via galactose-modified supramolecular two-dimensional glycomaterial. Hai-Na Xie†, Yu-Yuan Chen†, Guo-Biao Zhu, Hai-Hao Han*, Xile Hu, Zhi-Qiang Pan, Yi Zang, Donghao Xie*, Xiao-Peng He, Jia Li*, Tony D. James* Chem. Commun. 2022, 58, 5029-5032. DOI 10.1039/D1CC06809A
Fluorescent probes for the detection of disease-associated biomarkers Wei-Tao Dou†, Hai-Hao Han†, Adam C. Sedgwick, Guo-Biao Zhu, Yi Zang, Xin-Rong Yang*, Juyoung Yoon*, Tony D. James*, Jia Li*, Xiao-Peng He* Sci. Bull. 2022, 67, 853-878. DOI 10.1016/j.scib.2022.01.014
Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications Luling Wu†, Jihong Liu†, Xue Tian†, Robin R. Groleau, Beidou Feng, Yonggang Yang, Adam C. Sedgwick, Hai-Hao Han*, Yang Wang, Han-Min Wang, Fang Huang, Steven D. Bull, Hua Zhang*, Chusen Huang*, Yi Zang, Jia Li, Xiao-Peng He, Ping Li*, Bo Tang, Tony D. James*, Jonathan L. Sessler* J. Am. Chem. Soc. 2022, 144, 174–183. DOI 10.1021/jacs.1c07954
A General Strategy to the Intracellular Sensing of Glycosidases using AIE-Based Glycoclusters Lei Dong†, Min-Yu Zhang†, Hai-Hao Han†, Yi Zang, Guo-Rong Chen, Jia Li*, Xiao-Peng He*, Sébastien Vidal* Chem. Sci. 2022, 13, 247-256. DOI 10.1039/D1SC05057E
Ferrocene-Labelled Electroactive Aptamer-Based Sensors (Aptasensors) for Glycated Haemoglobin Xue-Qing Feng†, Yi Ju†, Wei-Tao Dou*, Qing Li, Zhong-Gan Jin, Xiao-Peng He, Tony D. James*, Bang-Ce Ye* Molecules 2021, 26, 7077. DOI 10.3390/molecules26237077
Near-Infrared Light-Triggered Bacterial Eradication Using a Nanowire Nanocomposite of Graphene Nanoribbons and Chitosan-Coated Silver Nanoparticles Ming Zhou†, Hui-Qi Gan†, Guo-Rong Chen, Tony D James, Bin Zhang, Qiang Hu*, Fugui Xu*, Xi-Le Hu*, Xiao-Peng He, Yiyong Mai Front. Chem. 2021, 9, 767847. DOI 10.3389/fchem.2021.767847
Metal-organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics Pei-Hong Tong, Ling Zhu, Yi Zang, Jia Li*, Xiao-Peng He*, Tony D. James* Chem. Commun. 2021, 57, 12098-12110. DOI 10.1039/D1CC05157A
Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells Dan Zhao†, Hai-Hao Han†, Ling Zhu, Fang-Zhou Xu, Xing-Yu Ma, Jia Li, Tony D. James*, Yi Zang*, Xiao-Peng He*, Chengyun Wang* ACS Appl. Bio Mater. 2021, 4, 7016–7024. DOI 10.1021/acsabm.1c00673
Graphene nanoribbon-based supramolecular ensembles with dual-receptor targeting function for targeted photothermal tumor therapy Wei-Tao Dou‡, Fugui Xu‡, Chen-Xi Xu, Jie Gao, Hongbo Ru, Xiangfeng Luan, Jiacheng Zhang, Ling Zhu, Adam Sedgwick, Guo-Rong Chen, Yi Zang, Tony D. James, He Tian, Jia Li*, Yiyong Mai*, Xiao-Peng He* Chem. Sci. 2021, 12, 11089-11097. DOI 10.1039/D1SC02154K
Small-molecule fluorescence-based probes for interrogating major organ diseases Hai-Hao Han, He Tian Jr., Yi Zang, Adam C Sedgwick, Jia Li*, Jonathan L Sessler*, Xiao-Peng He*, Tony D. James* Chem. Soc. Rev. 2021, 50, 9391-9429. DOI 10.1039/D0CS01183E
TCF-ALP: a fluorescent probe for the selective detection of Staphylococcus bacteria and application in “smart” wound dressings Lauren Gwynne, George T. Williams, Kai-Cheng Yan, Bethany L. Patenall, Jordan E. Gardiner, Xiao-Peng He, Jean-Yves Maillard, Tony D. James*, Adam. C. Sedgwick*, A. Toby. A. Jenkins* Biomater. Sci. 2021, 9, 4433-4439. DOI 10.1039/d0bm01918f
In vitro studies of deferasirox derivatives as potential organelle-targeting traceable anti-cancer therapeutics Axel Steinbrueck, Adam C. Sedgwick, Hai-Hao Han, Michael Y. Zhao, Sajal Sen, Dan-Ying Huang, Yi Zang, Jia Li*, Xiao-Peng He*, Jonathan L. Sessler * Chem. Commun 2021, 57, 5678-5681. DOI 10.1039/d0cc08156f
Low-dimensional nanomaterials for antibacterial applications Xi-Le Hu†, Ying Shang†, Kai-Cheng Yan†, Adam C. Sedgwick, Hui-Qi Gan, Guo-Rong Chen, Xiao-Peng He*, Tony D. James*, Daijie Chen* J. Mater. Chem. B 2021, 9, 3640-3661. DOI 10.1039/d1tb00033k
The Evaluation of Ester Functionalised TCF-Based Fluorescent Probes for the Detection of Bacterial Species Lauren Gwynne†, George T. Williams†, Kai-Cheng Yan, Jordan E. Gardiner, Kira L. F. Hilton, Bethany L. Patenall, Jennifer R. Hiscock, Jean-Yves Maillard, Xiao-Peng He, Tony D. James*, Adam C. Sedgwick*, A. Toby A. Jenkins* Isr. J. Chem. 2021, 61, 234-238. DOI 10.1002/ijch.202000105
Stimulus-responsive water soluble synthetic nanographene Shuang Ma‡, Yan-Peng Zhu‡, Wei-Tao Dou, Ying Chen, Xiao-Peng He, Jiao-Bing Wang* Sci. China Chem. 2021, 64, 576–580 . DOI 10.1007/s11426-020-9916-7
Fluorescent probes for the imaging of lipid droplets in live cells He Tian Jr.†, Adam C. Sedgwick†, Hai-Hao Han†, Sajal Sen, Guo-Rong Chen, Yi Zang, Jonathan L. Sessler*, Tony D. James*, Jia Li*, Xiao-Peng He* Coord. Chem. Rev. 2021, 427, 213577. DOI 10.1016/j.ccr.2020.213577
Deferasirox (ExJade): An FDA-Approved AIEgen Platform with Unique Photophysical Properties Adam C. Sedgwick, Kai-Cheng Yan, Daniel N. Mangel, Ying Shang, Axel Steinbrueck, Hai-Hao Han, James T. Brewster II, Xi-Le Hu, Dylan W. Snelson, Vincent M. Lynch, He Tian, Xiao-Peng He*, and Jonathan L. Sessler* J. Am. Chem. Soc. 2021, 143, 1278–1283. DOI 10.1021/jacs.0c11641
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