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研究领域

(1)多肽抗肿瘤药物; (2)基于多肽类的各种生物酶的抑制剂; (3)生物大分子的组装与识别。

近期论文

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Wu, J.; Zou, Y.; Li, C.; Sicking, W.; Piantanida, I.; Yi, T.; Schmuck, C. A molecular peptide beacon for the ratiometric sensing of nucleic acids. J. Am. Chem. Soc. 2012, 134, 1958-1961. Wu, J.; Zawistowski, A.; Ehrmann, M.; Yi, T.; Schmuck, C. Peptide functionalized polydiacetylene liposomes act as a fluorescent turn-on sensor for bacterial lipopolysaccharide. J. Am. Chem. Soc. 2011, 133, 9720-9723. (Highlighted by “Chemical & Engineering” News) Wu, Y.; Yang, T.; Li, X.; Wu, J.; Yi, T.; Li, F.; Huang, C.; Fan, X. Novel derivatives of niclosamide synthesis its bioactivity and interaction with schistosoma japonicum cercariae. Dyes and Pigment 2011, 88, 326-332. Yu, X.; Liu, Q.; Wu, J.; Zhang, M.; Cao, X.; Zhang, S.; Wang, Q.; Chen, L.; Yi, T. Sonication-Triggered instantaneous gel-to-gel transformation. Chem. Eur. J. 2010, 16, 9099-9106. Wang, Q.; Wu, J.; Gong, Z.; Zou, Y.; Yi, T.; Huang, C. From vesicles to solid spheres: terminal functional group induced morphology modification. Soft Matter 2010, 6, 2679-2684. Shu, T.; Wu, J.; Zou, Y.; Liu, K.; Chen, L.; Yi, T. Zn2+ Cation triggers self-assembly of cyclen into a stable metallogel. Front. Chem. China 2010, 5, 184-192. (邀请) Wu, J.; Hu, H.; Yi, T.; Li, F.; Huang, C. Self-assembly of peptide-based multi-color gels triggered by up-conversion rare earth nanoparticles. Chem. Comm. 2009, 8, 4100-4102. Wu, J.; Yi, T.; Xia, Q.; Zou, Y.; Liu, F.; Shu, T.; Dong, J.; Li, F.; Huang, C. Tunable gel formation by both sonication and thermal processing in a cholesterol-based self-assembly system. Chem. Eur. J. 2009, 15, 6234-6243. Wu, J.; Yi, T.; Zou, Y.; Shu, T.; Liu, F.; Yan, H.; Li, F.; Zhou, Z.; Huang, C. Gelation induced reversible syneresis via structural evolution. J. Mater. Chem. 2009, 19, 3971-3978. Chen, L.; Wu, J.; Yuwe, L.; Shu, T.; Xu, M.; Zhang, M.; Yi, T. Inclusion of tetracycline hydrochloride within supramolecular gels and its controlled release to bovine serum albumin. Langmuir 2009, 25, 8434-8438. Piao, X.; Zou, Y.; Wu, J.; Li C.; Yi, T. Multiresponsive switchable diarylethene and its application in bioimaging. Org. Lett. 2009, 11, 3818-3821. Wu, J.; Yi, T.; Shu, T.; Yu, M.; Zhou, Z.; Xu, M.; Zhou, Y.; Zhang, H.; Han, J.; Li, F.; Huang, C., Ultrasound switch and thermal self-repair of morphology and surface wettability in cholesterol-based self-assembly system. Angew. Chem., Int. Ed. 2008, 47, 1063-1067. (Highlighted by “Nature China”) Zou, Y.; Yi, T.; Xiao, S.; Li, F.; Li, C.; Gao, X.; Wu, J.; Yu, M.; Huang, C. Cells Amphiphilic diarylethene as a photoswitchable probe for imaging living cells. J. Am. Chem. Soc. 2008, 130, 15750-15751. Shu, T.; Wu, J.; Lu, M.; Chen, L.; Yi, T.; Li, F.; Huang, C. Tunable red-green-blue fluorescent organogels on the basis of intermolecular energy-transfer. J. Mater. Chem. 2008, 18, 886-893. (Cover Image; News: chemistry world). Zhou, Y.; Xu, M.; Wu, J.; Yi, T.; Han, J.; Xiao, S.; Li, F.; Huang, C. A novel photo responsive organogel based on azobenzene. J. Org. Phy. Chem. 2008, 21, 338-343. Xiao, S.; Zou, Y.; Wu, J.; Zhou, Y.; Yi, T.; Li, F.; Huang, C. Hydrogen bonding assisted switchable fluorescence in self-assembled complexes containing diarylethene: controllable fluorescent emission in the solid state. J. Mater. Chem. 2007, 17, 2483-2489. Yang, H.; Yi, T.; Zhou, Z.; Zhou, Y.; Wu, J.; Xu, M.; Li, F.; Huang, C. Switchable fluorescent organogels and mesomorphic superstructure based on naphthalene derivatives. Langmuir, 2007, 23, 8224-8230. Mu, X.; Zou, J.; Zeng R.; Wu, J. Mn(III)-Promoted cyclization of substituted thioformanilides under microwave irradiation: a new reagent for 2-substituted benzothiazoles. Tetrahedron Lett. 2005, 46, 4345-4347."

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