赵春常 - 华东理工大学 - 化学与分子工程学院

个人简介

1994-2001年就读于天津大学，并分别获得本科和硕士学位 2001-2004年就读于中科院理化技术研究所，并获得博士学位，师从佟振合院士、吴骊珠院士 2005年1月至2008年7月于美国罗彻斯特大学从事博士后研究 2008年9月起，华东理工大学精细化工研究所担任副教授、教授

研究领域

研究兴趣主要围绕国家健康领域的重大需求，创制新型分子探针并探讨其在重大疾病的快速、高效、精准诊疗等方面的应用，以期为医学和生命科学研究提供科学和技术支撑。研究涉及到有机合成化学、高分子化学、超分子化学、光化学和光物理、材料化学、药物化学、化学生物学等领域。

近期论文

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Tianli Zhu, Ning Ren, Xia Liu, Yan Dong, Rongchen Wang, Jinzhu, Gao, Jie Sun, Ying Zhu, Lihua Wang, Chunhai Fan, He Tian, Jiang Li,* Chunchang Zhao,* “Probing the Intracellular Dynamics of Nitric Oxide and Hydrogen Sulfide Using an Activatable NIR II Fluorescence Reporter”, Angew. Chem. Int. Ed.2021, 10.1002/anie.202015650. Rongchen Wang, Xianfeng Gu, Qizhao Li, Jie Gao, Ben Shi, Ge Xu, Tianli Zhu, He Tian, Chunchang Zhao,* “Aggregation Enhanced Responsiveness of Rationally Designed Probes to Hydrogen Sulfide for Targeted Cancer Imaging”, J. Am. Chem. Soc. 2020, 142, 15084-15090. Ge Xu, Wei Guo, Xianfeng Gu, Zhijun Wang, Rongchen Wang, Tianli Zhu, He Tian, Chunchang Zhao,* “Hydrogen Sulfide-Specific and NIR-Light-Controllable Synergistic Activation of Fluorescent Theranostic Prodrugs for Imaging-Guided Chemo-Photothermal Cancer Therapy”, CCS Chem.2020, 2, 527-538. Ben Shi, Ning Ren, Luyan Gu, Ge Xu, Rongchen Wang, Tianli Zhu, Ying Zhu,* Chunhai Fan,* Chunchang Zhao,* He Tian, “Theranostic Nanoplatform with Hydrogen Sulfide Activatable NIR Responsiveness for Imaging-Guided On-Demand Drug Release”, Angew. Chem. Int. Ed.2019, 58, 16826-16830. Rongchen Wang, Jian Chen, Jie Gao, Ji-An Chen, Ge Xu, Tianli Zhu, Xianfeng Gu, Zhiqian Guo, Wei-Hong Zhu and Chunchang Zhao,* “A Molecular Design Strategy toward Enzyme-Activated Probes with Near-Infrared I and II Fluorescence for Targeted Cancer Imaging”, Chem. Sci., 2019, 10, 7222-7227. Rongchen Wang, Kaikai Dong, Ge Xu, Ben Shi, Tianli Zhu, Ping Shi,* Zhiqian Guo, Wei-Hong Zhu, Chunchang Zhao,* “Activatable Near-Infrared Emission-Guided On-Demand Administration of Photodynamic Anticancer Therapy with a Theranostic Nanoprobe”, Chem. Sci., 2019, 10, 2785–2790. Ge Xu, Qinglong Yan, Xiaoguang Lv, Ying Zhu,* Kai Xin, Ben Shi, Rongchen Wang, Jian Chen, Wei Gao, Ping Shi, Chunhai Fan,* Chunchang Zhao,* He Tian, “Imaging of Colorectal Cancers Using Activatable Nanoprobes with Second Near-Infrared Window Emission”, Angew. Chem. Int. Ed.2018, 57, 3626-3630. Ben Shi, Qinglong Yan, Jie Tang, Kai Xin, Jichao Zhang, Ying Zhu,* Ge Xu, Rongchen Wang, Jian Chen, Wei Gao, Tianli Zhu, Jiye Shi, Chunhai Fan,* Chunchang Zhao,* He Tian, “Hydrogen Sulfide-Activatable Second Near-Infrared Fluorescent Nanoassemblies for Targeted Photothermal Cancer Therapy”, Nano Lett.2018, 18, 6411–6416. Feiyi Wang, Ge Xu, Xianfeng Gu, Zhijun Wang, Zhiqiang Wang, Ben Shi, Cuifen Lu, Xueqing Gong, Chunchang Zhao,* “Realizing highly chemoselective detection of H2S in vitro and in vivo with fluorescent probes inside core-shell silica nanoparticles”, Biomaterials2018,159, 82-90. Yingchao Liu, Jie Tan, Yi Zhang, Jianfeng Zhuang, Mingxu Ge, Ben Shi, Jiao Li, Ge Xu, Shangchen Xu,* Chunhai Fan,* Chunchang Zhao,* “Visualizing glioma margins by real-time tracking of γ-glutamyltranspeptidase activity”, Biomaterials2018, 173, 1-10. Ben Shi, Xianfeng Gu, Qiang Fei, Chunchang Zhao,* “Photoacoustic Probes for Real-Time Tracking of Endogenous H2S in Living Mice”, Chem. Sci., 2017, 8, 2150-2155. Ben Shi, Xianfeng Gu, Zhijun Wang, Ge Xu, Qiang Fei, Jie Tang, Chunchang Zhao,* “Fine Regulation of Porous Architectures of Core−Shell Silica Nanocomposites Offers Robust Nanoprobes with Accelerated Responsiveness”, ACS Appl. Mater. Interfaces 2017, 9, 35588-35596. Chunchang Zhao,* Xiuli Zhang, Kaibin Li, Shaojia Zhu, Zhiqian Guo, Lili Zhang, Feiyi Wang, Qiang Fei, Sihang Luo, Ping Shi,* He Tian, Wei-Hong Zhu,* “Förster Resonance Energy Transfer Switchable Self-Assembled Micellar Nanoprobe: Ratiometric Fluorescent Trapping of Endogenous H2S Generation via Fluvastatin-Stimulated Upregulation”, J. Am. Chem. Soc. 2015, 137, 8490-8498. Feiyi Wang, Ying Zhu, Li Zhou, Liang Pan, Zhifen Cui, Qiang Fei, Sihang Luo, Dun Pan, Qing Huang, Rui Wang, Chunchang Zhao,* He Tian, Chunhai Fan,* “Fluorescent In Situ Targeting Probes for Rapid Imaging of Ovarian-Cancer Specific γ-Glutamyltranspeptidase”, Angew. Chem. Int. Ed.2015, 54, 7349-7353. Feiyi Wang, Li Zhou, Chunchang Zhao,* Rui Wang, Qiang Fei, Sihang Luo, Zhiqian Guo, He Tian, Weihong Zhu,* “A dual-response BODIPY-based fluorescent probe for the discrimination of glutathione from cysteine and homocystein”, Chem. Sci.2015, 6, 2584-2589.