研究领域
主要研究方向: (1)中药物质基础与药效关系的研究与中药新药研发,在中药质量分析、提取分离、药理活性、作用机制与中药新药筛选等方面开展了大量工作,多项成果在中药企业应用转化。(2)化学计量学方法及近红外技术的应用研究,在烟草、牛奶等天然产物领域运用近红外技术进行质量分析与监控,得到了业内的广泛关注与高度认可。
近期论文
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Li-Guo Zhang, Xin Zhang, Li-Jun Ni,* Zhi-Bin Xue, Xin Gu, Shi-Xin Huang, Rapid identification of adulterated cow milk by non-linear pattern recognition methods based on near infrared spectroscopy , Food Chemistry, 2014,145:342-348(该文自2013年12月网上登出-2014年7月30号,下载900多次,受到业内广泛关注)
Li-Jun Ni, Xiao-Ling Xu, Li-Guo Zhang*, Wan-Zhong Shi, Quantitative evaluation of the in vitro effect and interactions of active fractions in Yaotongning-based formulae on prostaglandin E2 production, Journal of Ethnopharmacology, 2014,154:807-817
Zhang,L.G., Ouyang,X.W., Ni L.J., Shi, W.Z., Preparation and evaluation of the microcapsule containing volatile oil of Herba Schizonepetae by emulsion solvent diffusion method. Transactions of Tianjin University, 2014. 20:103-111.
Li-Guo Zhang, Xiao-Wen Ouyang, Ting-Ting Wu, Li-Jun Ni*, Wan-Zhong Shi, Quantitative evaluation of in vitro effects and interactions of active fractions in a Chinese medicinal formula (Yaotongning Capsule) on rat chondrocytes, Journal of Ethnopharmacology,DOI: 10.1016/j.jep.2014.07.011
Zhang Liguo, Fang Congying, Ouyang Xiaowen, Ni Lijun*, Simultaneous Determination of Saponins in Radix Glycyrrhizae, Notoginseng and Ginseng by High Performance Liquid Chromatography, Transactions of Tianjin University, 2013, 19(6): 430-435
L.G. Zhang, C.Zhang, L.J. Ni*, Y.J. Yang and C.M. Wang, Rectification extraction ofChineseherbs volatile oils and comparison with conventional steam distillation,Separation and Purification Technology,2011,77:261-268
L.J. Ni, L. G. Zhang*, J. Xie and J. Q. Luo, Pattern recognition of Chinese flue-cured tobaccos by an improved and simplified K- nearest neighbors classification algorithm on near infrared spectra,Anal. Chim. Acta,2009, 633: 43-50
L.J. Ni, L. G. Zhang*, J. Hou, W. Z. Shi and M. L. Guo, A strategy for evaluating antipyretic efficacy of Chinese herbal medicines based on UV spectra fingerprints,Journal of Ethnopharmacology,2009, 124: 79-8...