个人简介
中国免疫学学会会员,毕业于中山大学中山医学院,获免疫学博士学位,导师周洁教授(国家杰青)。研究成果及科研项目:目前在国内外主流学术期刊发表论文20余篇,其中以第一作者或通讯作者在(Oncogene. 2017, IF:7.932), (J Immunol. 2017,IF: 4.985), (Mol Cell Biol. 2015, IF: 4.427),(Front Immunol. 2019, IF: 4.716),(Sci Rep. 2019, IF: 4.011)等国际知名期刊上发表研究性论文。主持在研科研项目多项,包括国家级(国家自然科学基金青年项目,3180050156、IRF4调控c-Myc表达对肿瘤中髓系抑制性细胞分化的影响及机制研究、2019/01-2021/12、23万)、省级(广东省自然科学基金2项)、市局级(广东省医学科研基金)和厅级(广东省教育厅特色创新项目)等多个级别科研项目,研究经费充足。同时为广州医科大学高水平大学学术骨干培育对象。
研究领域
肿瘤免疫及抗感染免疫,主要从事免疫细胞包括髓源性抑制细胞(MDSCs)、树突状细胞(DCs)、Tfh细胞等在免疫相关疾病(肿瘤和感染等)发生发展中的作用,及相关分子调控机制研究。
近期论文
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(1) Quan Yang#,Xing Li, Yingjiao Cao, Qiang Xiao, Jianyang Wei, Jie Zhou*. IRF7 regulates the development of granulocytic myeloid-derived suppressor cells through S100A9 transrepression in cancer.Oncogene, 2017 25;36(21):2969-2980. (IF: 7.932)
(2) Zitao Li#,,Anping Peng#, Yuanfa Feng#,Xiaona Zhang,Fenghua Liu,Chuangqi Chen, Xin Ye, Jiale Qu,Chenxi Jin, Mei Wang, Huaina Qiu, Yanwei Qi, Jun Huang*,Quan Yang*(通讯).Detection of T lymphocyte subsets and related functional molecules in follicular fluid of patients with polycystic ovary syndrome.Sci Rep.2019. 15;9(1):6040 (IF=4.011)
(3) Quan Yang#, Jiale Qu#, Chenxi Jin, Yuanfa Feng, Shihao Xie, Jinxin Zhu, Gaoshen Liu, Hongyan Xie, Huaina Qiu, Yanwei Qi, Jianbing Mu* and Jun Huang* Schistosoma japonicum Infection Promotes the Response of Tfh Cells Through Down-Regulation of Caspase-3–Mediating Apoptosis,Front. Immunol., 13 September 2019 (IF=4.716)
(4) Quan Yang#, Huaina Qiu#, Hongyan Xie#, Yanwei Qi, Hefei Cha, Jiale Qu, Mei Wang, Yuanfa Feng, Xin Ye, Jianbing Mu*and Jun Huang*,A Schistosoma japonicum Infection Promotes the Expansion of Myeloid-DerivedSuppressor Cells by Activating the JAK/STAT3 Pathway,J Immunol.2017 15;198(12):4716-4727.(IF: 4.985)
(5) Quan Yang#,Jianyang Wei, Limei Zhong, Maohua Shi, Pan Zhou, Shengkai Zuo, Kang Wu, Mingjiang Zhu, Xi Huang, Ying Yu, Hui Zhang, Huiyong Yin , Jie Zhou*. Cross-talk between HDAC4 and STAT6 in the transcriptional regulation of arginase-1 during mouse dendritic cell differentiation.Molecular and Cellular Biology, 2015 Jan;35(1):63-75. (IF: 4.427)