个人简介
学习经历
2006.9-2010.7:山东大学药学院药学专业学士
2011.9-2017.7:山东大学药学院免疫药物学专业博士
工作经历
2010.9-2011.7:山东大学研究生支教团,平型关寄宿制学校教师
2017.8-至今:鲁东大学生命科学学院讲师
研究领域
1. 沙门氏菌分离、鉴定及耐药性研究:探究沙门氏菌分离鉴定方法、沙门氏菌耐药表型及其与耐药基因的关系,阐明沙门氏菌耐药机制
2. 肝脏肿瘤免疫学:探究天然模式识别受体在肝癌转移中的作用及分子机制,为肝癌治疗提供理论依据
近期论文
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1. Xin Yu, Peixiang Lan, Xuben Hou, Qiuju Han, Nan Lu, Tao Li, Chenwei Jiao, Jian Zhang, Cai Zhang*, Zhigang Tian*. HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1bproduction via suppressing NF-kB pathway and ROS production, Journal of Hepatology, 2017; 66(4):693-702.
2. Xin Yu#, Hongru Zhang#, Linyan Yu, Meifang Liu, Qiuju Han, Jian Zhang, Zhigang Tian, Cai Zhang*. Intestinal lamina propria CD4+T cells promote bactericidal activity of macrophages via galectin-9 and Tim-3 interaction duringSalmonella typhimuriuminfection. Infection and Immunity, 2018;86(8).
3. 于馨,张彩*.炎症小体信号通路的负调控.生物化学与生物物理进展, 2014;41(1):87-95.
4. Zhixia Zhou,Xin Yu, Jian Zhang, Zhigang Tian, Cai Zhang*.TLR7/8 agonists promote NK-DC cross-talk to enhance NK cell anti-tumor effects in hepatocellular carcinoma. Cancer Letters, 2015; 369(2):298-306.
5. Qie Guo, Peixiang Lan,Xin Yu, Qiuju Han, Jian Zhang, Zhigang Tian, Cai Zhang*. Immunotherapy for hepatoma using a dual-function vector with both immunostimulatory and Pim-3-silencing effects. Molecular Cancer Therapeutics, 2014; 13(6):1503-1513.