个人简介
工学博士,教授、博士生导师。南京理工大学学士学位、浙江大学硕士学位、日本国立山口大学博士学位,上海市浦江计划学者。先后在中石化、日本冈山大学、美国加州大学戴维斯分校从事研究工作。2006年至今任职华东理工大学生物工程学院和生物反应器工程国家重点实验室。作为课题负责人主持了973、863、国家自然科学基金课题,以及中石油等工业应用课题数十项。现任SCI期刊Applied Biochemistry and Biotechnology副主编、Biofuels, Bioproducts and Biorefining和Bioprocess and Biosystems Engineering编委、Springer和Elsevier学术期刊客座编辑,亚洲生物技术联合会生物能源与生物炼制分会理事,生物反应器工程国家重点实验室副主任。作为秘书长或共同主席组织了亚洲生物技术大会、生物过程与生物技术国际研讨会等多次国际学术会议。
学历
1997-2001 工学博士,日本国立山口大学物质工学专业
1995-1997 工学硕士,浙江大学化学工程专业
1980-1984 工学学士,南京理工大学化学工程专业
研究经历
2006-现在 华东理工大学生物工程学院教授、博士生导师
2002-2006 美国加州大学戴维斯分校博士后研究员
2001-2002 日本国立冈山大学工学部客座研究员
1984-1995 中石化齐鲁石化研究院工程师、课题组长
研究领域
研究领域聚焦于木质纤维素生物炼制和生物能源方向的应用基础研究。提出了木质纤维素干法生物炼制技术,在液体燃料和生物基化学品生产上显示了巨大的技术优势和环境友好性,奠定了以木质纤维素替代粮食和石油资源的可持续生物与化学工业的技术基础;对一系列生物炼制工业发酵菌株的代谢工程改造,成倍提高了生物催化和发酵效率,达到了迄今国内外最高水平的生物炼制转化、能耗和排放指标;独特的生物脱毒菌株和代谢机制的发现,极大提高了生物炼制过程效率和环境质量,实现了抑制物脱毒关键瓶颈的突破;提出了基于严格热力学和流变学基础上的生物炼制流程模拟和计算流体力学模型,实施了多项面向产业化规模的工艺包设计和工业应用。在生物航空燃油、氨基酸生物炼制等前沿领域取得重大进展,并开拓了重金属土壤污染的生物炼制治理新方向。
1. 木质纤维素原料生产液体生物燃料(燃料乙醇、生物油脂)的过程合成、模拟、优化及其工业示范;
2. 能源微生物的代谢路径重构与整合生物加工细胞;
3. 基于纤维素和果聚糖生物质的关键中间体化学品生物制造。
近期论文
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Gang Liu, Qiang Zhang, Hongxing Li, Abdul Sattar Qurishi, Jian Zhang, Xiaoming Bao*, Jie Bao*. Dry biorefining maximizes the potentials of simultaneous saccharification and co-fermentation for cellulosic ethanol production. Biotechnology and Bioengineering (IF 4.481), 2017, DOI: 10.1002/bit.26444.
Zhongyang Qiu, Qiuqiang Gao, Jie Bao*. Engineering Pediococcus acidilactici with xylose assimilation pathway for high titer cellulosic L-lactic acid fermentation. Bioresource Technology (IF 5.651), 2017, doi.org/10.1016/j.biortech.2017.09.117.
Zhongyang Qiu, Qiuqiang Gao, Jie Bao*. Constructing xylose-assimilating pathways in Pediococcus acidilactici for high titer D-lactic acid fermentation from corn stover feedstock. Bioresource Technology (IF 5.651), 2017, doi.org/10.1016/j.biortech.2017.05.128.
Gang Liu, Jie Bao*. Maximizing cellulosic ethanol potentials by minimizing wastewater generation and energy consumption: Competing with corn ethanol. Bioresource Technology (IF 5.651), 2017, doi.org/10.1016/j.biortech.2017.08.070.
Gang Liu, Jie Bao*. Evaluation of electricity generation from lignin residue and biogas in cellulosic ethanol production. Bioresource Technology (IF 5.651), 2017, 243:1232-1236.
Ruimiao Yao, Weiliang Hou, Jie Bao*. Complete oxidative conversion of lignocellulose derived non-glucose sugars to sugar acids by Gluconobacter oxydans. Bioresource Technology (IF 5.651), 2017, 244: 1188-1192.
Hongsen Zhang, Xushen Han, Chengxiang Wei, Jie Bao*. Oxidative production of xylonic acid using xylose in distillation stillage of cellulosic ethanol fermentation broth by Gluconobacter oxydans. Bioresource Technology (IF 5.651), 2017, 224:573-580.
Ping-Ping Zhou, Jiao Meng, Jie Bao*. Fermentative production of high titer citric acid from corn stover feedstock after dry dilute acid pretreatment and biodetoxification. Bioresource Technology (IF 5.651), 2017, 224:563-572.
Shuai Shao, Jian Zhang*, Weiliang Hou, Abdul Sattar Qureshi, Jie Bao. Lower pressure heating steam is practical for the distributed dry dilute sulfuric acid pretreatment. Bioresource Technology (IF 5.651), 2017, 238: 744-748.
Abdul Sattar Qureshi, Jian Zhang*, Leonardo da Costa Sousa*, Jie Bao*. An antibacterial peptide secreted by Pediococcus acidilactici enables efficient cellulosic open L-lactic acid fermentation. ACS Sustainable Chemistry & Engineering (IF 5.951), 2017, DOI: 10.1021/acssuschemeng.7b02212.
Yi Jiang, Kuimei Liu, Hongsen Zhang, Yingli Wang, Quanquan Yuan, Ning Su, Jie Bao, Xu Fang*. Gluconic acid production from potato waste by Gluconobacter oxidans using sequential hydrolysis and fermentation. ACS Sustainable Chemistry & Engineering (IF 5.951), 2017, 5: 6116-6123.
Xia Wang, Qiuqiang Gao, Jie Bao*. Enhancement of furan aldehydes conversion in Zymomonas mobilis by elevating dehydrogenase activity and cofactor regeneration. Biotechnology for Biofuels (IF 5.203), 2017, 10:24.
Dong Tian, Jinguang Hu, Jie Bao, Richard P. Chandra, Jack N. Saddler, CanhuiLuhongyang. Lignin valorization: lignin nanoparticles as high-value bio-additive for multifunctional nanocomposites. Biotechnology for Biofuels (IF 5.203), 2017, 10:192.
Shuai Shao, Jian Zhang, Jie Bao*. Reduction of reactor corrosion by eliminating liquid phase existence in dry dilute acid pretreatment of corn stover. Energy & Fuels (IF 3.091), 2017, 31(6): 6140-6144.
Qiang Zhang, Jie Bao*. Industrial cellulase performance in the simultaneous saccharification and co-fermentation (SSCF) of corn stover for high titer ethanol production. Bioresources and Bioprocessing, 2017, 4:17.
Juan Wang, Mingshan Hu, Huizhan Zhang*, Jie Bao*. Converting chemical oxygen demand (COD) of cellulosic ethanol fermentation wastewater into microbial lipid by oleaginous yeast Trichosporon cutaneum. Applied Biochemistry and Biotechnology (IF 1.751), 2017, 182:1121-1130.
Hongsen Zhang, Gang Liu, Jian Zhang, Jie Bao*. Fermentative production of high titer gluconic and xylonic acids from corn stover feedstock by Gluconobacter oxydans and techno-economic analysis. Bioresource Technology (IF 5.651), 2016, 219:123-131.
Hongsen Zhang, Jian Zhang, Jie Bao*. High titer gluconic acid fermentation by Aspergillus niger from dry dilute acid pretreated corn stover without detoxification. Bioresource Technology (IF 5.651), 2016, 203:211-219.
Juan Wang, Qiuqiang Gao, Huizhan Zhang, Jie Bao*. Inhibitor degradation and lipid accumulation potentials of oleaginous yeast Trichosporon cutaneum using lignocellulose feedstock. Bioresource Technology (IF 5.651), 2016, 218:892-901.
Jian Zhang, Shuai Shao, Jie Bao*. Long term storage of dilute acid pretreated corn stover feedstock and ethanol fermentability evaluation. Bioresource Technology (IF 5.651), 2016, 201:355-359.