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个人简介

科研情况: [1]国家自然科学基金青年科学基金项目,81703014,2018/01-2020/12,主持 [2]天津市教委科研计划项目,2017KJ010,2017/05-2020/04,主持 [3]国家自然科学基金面上项目,81673647,2017/01-2020/12,第二参与人 [4]国家自然科学基金青年科学基金项目,31601203,2017/01-2019/12,第二参与人 [5]中国博士后科学基金面上项目,2015M570229,2015-2016,主持,已结题

研究领域

[1]抗肿瘤药物药理作用研究 [2]抗肿瘤药物的剂型研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.LiuZ,ZhengQ,ChenWZ,WuM,PanGJ,YangK,LiXZ,ManSL,TengYO,YuP,GaoWY.ChemosensitizingeffectofParisSaponinIonCamptothecinand10-hydroxycamptothecininlungcancercellsviap38MAPK,ERK,andAktsignalingpathways.EuropeanJournalofMedicinalChemistry,2017,125:760-769. 2.LiuZ,ZhengQ,ChenWZ,ManSL,TengYO,MengX,ZhangYM,YuP,GaoWY.ParissaponinIinhibitsproliferationandpromotesapoptosisthroughdown-regulatingAKTactivityinhumannon-small-celllungcancercellsandinhibitingERKexpressioninhumansmall-celllungcancercells.RSCAdvances,2016,6:70816-70824. 3.TengYO,WangLX,LiuH,YuanY,ZhangQ,WuM,WangLY,WangHM,LiuZ*,YuP*.3"-Geranyl-mono-substitutedchalconeXanthoangelovlinducesapoptosisinhumanleukemiaK562cellsviaactivationofmitochondrialpathway.Chemico-BiologicalInteractions,2017,261:103-107. 4.LiuZ,WangJY,GaoWY,ManSL,GuoHM,ZhangJZ,LiuCX.FormulationandinvitroabsorptionanalysisofRhizomaparidissteroidalsaponins.InternationalJournalofPharmaceutics,2013,441(1-2):680-686. 5.LiuZ,LiHF,FanYY,LiuYX,ManSL,YuP,GaoWY.CombinationtreatmentwithRhizomaParidisandRhizomaCurcumalongaextractsand10-hydroxycamptothecinenhancestheantitumoreffectinH22tumormodelbyincreasingtheplasmaconcentration.Biomedicine&Pharmacotherapy,2016,83:627-634. 6.LiuZ,GaoWY,ManSL,ZhangY,LiHF,WuSS,ZhangJZ,LiuCX.SynergisticeffectsofRhizomaParidisandRhizomaCurcumalongaondifferentanimaltumormodels.EnvironmentalToxicologyandPharmacology,2014,38(1):31-40. 7.LiuZ,GaoWY,JingSS,ZhangY,ManSL,WangY,ZhangJZ,LiuCX.Correlationamongcytotoxicity,hemolyticactivityandthecompositionofsteroidalsaponinsfromParisL..JournalofEthnopharmacology,2013,149(2):422-430. 8.LiuZ,WangJY,GaoWY,ManSL,WangY,LiuCX.PreparativeseparationandpurificationofsteroidalsaponinsinParispolyphyllavar.yunnanensisbymacroporousadsorptionresins.PharmaceuticalBiology,2013,51(7):899-905. 9.LiuZ,ZhangJZ,GaoWY,LiuCX.AntinociceptiveactivityandChemicalcompositionofWei-Chang-An-Wanextracts.PharmaceuticalBiology,2013,51:790-797. 10.LiuZ,LiN,GaoWY,ManSL,YinSS,LiuCX.Comparativestudyonhemostatic,cytotoxicandhemolyticactivitiesofdifferentspeciesofParisL..JournalofEthnopharmacology,2012,142(3):789-794. 11.LiuZ,GaoWY,ManSL,WangJY,LiN,YinSS,WuSS.,LiuCX.Pharmacologicalevaluationofsedative-hypnoticactivityandgastro-intestinaltoxicityofRhizomaParidissaponins.JournalofEthnopharmacology,2012,144(1):67-72.

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