研究领域
现从事抗骨质疏松药物、抗肿瘤药物的合成及药物工艺研究工作。
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Guangyu Xu, Chunhao Yang, et al. Catechol-bisphosphonate conjugates: new potential chelating agents for metal intoxication therapy. Chinese Chem. Lett. 2004, 15(12), 1403-1406.
Guangyu Xu, Yuyuan Xie, et al. A facile and direct synthesis of alendroante from pyrrolidone. Org. Prep. & Proc. Int. 2004, 36(2), 185-7.
Guangyu Xu, Chunhao Yang, et al. Synthesis of new potential chelating agents catechol-bisphosphonate conjugates for metal intoxication therapy. Heteroatom Chem. 2004, 15(3), 251-257.
Huasheng Ding, Guangyu Xu, et al. Catechol–bisphosphonate conjugates: new types of chelators for metal intoxication therapy. Heteroatom Chem. 2004, 15(7), 549-555.
Chunhao Yang, Guangyu Xu, et al. Benzothiophenes containing a piperazine side chain as selective ligands for the estrogen receptor α and their bioactivities in vivo. Bioorg. Med. Chem. Lett. 2005, 15(5), 1505-1507.
Bo Liu, Guangyu Xu, et al. A novel and facile method to synthesize (R) and (S)-2-methylpiperazine. Synthetic Communications 2004 34(22), 4111-4118.
Guangyu Xu, Yi Zhou, et al. A convenient synthesis of antibacterial Linezolid from ascorbic acid. Chinese Chem. Lett. 2006, 17(3) 302-304
Guangyu Xu, Yi Zhou, Gaolei Zuo, Yongjun Jiang. An improved procedure for synthesis of a-asarone. Org. Prep. & Proc. Int.. 2007, 39 (5), 514-517.
Guangyu Xu, Yi Zhou, Chunhao Yang, Yuyuan Xie. An effective synthesis of linezolid and eperezolid using (S)-glyceraldehyde acetonide as chiral building block. Heteroatom Chemistry 2008, 19 (3), 316-319.
Guangyu Xu, Chang Liu, Wei Zhang, Gaolei Zuo. A practical synthesis of α-asarone via iodine-catalyzed isomerization of α/β-asarone. Org. Prep. & Proc. Int.. 2009, 41(2), 152-155.
徐广宇，周伊，左高磊，蒋勇军. 1-氨基-7-甲氧基-β-咔啉及其1-烷氧羰基氨基衍生物的合成和初步抗肿瘤活性研究. 有机化学, 2009, 29(10),1593-1597.
Long-Range’ Pummerer-Type Cyclization: A Simple and Facile Synthesis of 5-Vinyl-1,3-oxazoles Guangsyu Xu, Kaixiong Chen, Hongwei Zhou. Synthesis, 2009, (21) 3565-3570.
Guangyu Xu, Gaolei Zuo, Shihua Zhong, Wei Zhang. Synthesis and Hydroxyapatite Binding Activity of Bisphosphonate-Statin Conjugates. Lett. Org. Chem. 2009, 6(5), 419-423.
Kaixiong Chen, Chang Liu, Guangyu Xu.*A practical 1-dehydroge- nation of 4-3-keto- steroids with DDQ in the presence of TBDMSCl at room temperature. Steroids, 2010, 75, 513–16
Guangyu Xu, Kaixiong Chen, Hongwei Zhou. Sulfur-assisted propargyl–allenyl isomerizations and intramolecular cyclization for the synthesis of tricyclic thiophene derivatives. Tetrahedron Letters, 2010, 51(48), 6240-6242
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