Weibel, Douglas B. - University of Wisconsin-Madison

个人简介

Douglas B. Weibel is an Associate Professor of Biochemistry, Chemistry, and Biomedical Engineering at the University of Wisconsin-Madison. He received his B.S. degree in chemistry in 1996 from the University of Utah (with Prof. C. Dale Poulter). From 1996-1997 he was a Fulbright Fellow at Tohoku University, Japan and studied organometallic chemistry (with Prof. Yoshinori Yamamoto). He received his Ph.D. in chemistry from Cornell University in 2002 (with Prof. Jerrold Meinwald) for research in the fields of organic and analytical chemistry. During his graduate studies he was an intern at Orchid Biosciences Inc. (now Orchid Cellmark) and a visiting scientist at the Max Planck Institute for Chemical Ecology, Jena, Germany (with Prof. Wilhelm Boland). From 2002-2006 he was a postdoctoral fellow with Prof. George M. Whitesides at Harvard University where his research spanned the fields of chemistry, materials science and engineering, and microbiology. In 2005 he was a student in the Physiology Course ('Modern Cell Biology using Microscopic, Biochemical, and Computational Approaches') at the Marine Biological Laboratory at Woods Hole (Course Directors, Prof. Ron Vale and Prof. Tim Mitchison). Douglas is currently a visiting professor of physics at the University of Washington, Seattle and a principal scientist at Amazon, Inc (2014-2015). He has consulted for a range of public and privately-held companies in the areas of biotechnology, bioengineering, chemistry, and materials science, and has participated in a range of government advisory positions in the areas of biodefense, infectious diseases, and biomedicine. His research interests span the fields of biochemistry, biophysics, chemistry, materials science and engineering, and microbiology

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Microfluidics for High School Chemistry Students. Hemling M, Crooks JA, Oliver PM, Brenner K, Gilbertson J, Lisensky GC, Weibel DB. J Chem Educ. 2014 Jan 14;91(1):112-115. Agarose particle-templated porous bacterial cellulose and its application in cartilage growth in vitro. Yin N, Stilwell MD, Santos TM, Wang H, Weibel DB. Acta Biomater. 2015 Jan;12:129-38. doi: 10.1016/j.actbio.2014.10.019. Epub 2014 Oct 27. Localization of anionic phospholipids in Escherichia coli cells. Oliver PM, Crooks JA, Leidl M, Yoon EJ, Saghatelian A, Weibel DB. J Bacteriol. 2014 Oct;196(19):3386-98. doi: 10.1128/JB.01877-14. Epub 2014 Jul 7. Using liquid crystals to reveal how mechanical anisotropy changes interfacial behaviors of motile bacteria. Mushenheim PC, Trivedi RR, Weibel DB, Abbott NL. Biophys J. 2014 Jul 1;107(1):255-65. doi: 10.1016/j.bpj.2014.04.047. Polar localization of Escherichia coli chemoreceptors requires an intact Tol-Pal complex. Santos TM, Lin TY, Rajendran M, Anderson SM, Weibel DB. Mol Microbiol. 2014 Jun;92(5):985-1004. doi: 10.1111/mmi.12609. Epub 2014 May 2. Gyramides prevent bacterial growth by inhibiting DNA gyrase and altering chromosome topology. Rajendram M, Hurley KA, Foss MH, Thornton KM, Moore JT, Shaw JT, Weibel DB. ACS Chem Biol. 2014 Jun 20;9(6):1312-9. doi: 10.1021/cb500154m. Epub 2014 Apr 22. Dynamic self-assembly of motile bacteria in liquid crystals. Mushenheim PC, Trivedi RR, Tuson HH, Weibel DB, Abbott NL. Soft Matter. 2014 Jan 7;10(1):88-95. doi: 10.1039/c3sm52423j. Bacterial cellulose as a substrate for microbial cell culture. Yin N, Santos TM, Auer GK, Crooks JA, Oliver PM, Weibel DB. Appl Environ Microbiol. 2014 Mar;80(6):1926-32. doi: 10.1128/AEM.03452-13. Epub 2014 Jan 17. Studying biomolecule localization by engineering bacterial cell wall curvature. Renner LD, Eswaramoorthy P, Ramamurthi KS, Weibel DB. PLoS One. 2013 Dec 31;8(12):e84143. doi: 10.1371/journal.pone.0084143. eCollection 2013. A chemist building paths to cell biology. Weibel DB. Mol Biol Cell. 2013 Nov;24(21):3264-6. doi: 10.1091/mbc.E13-07-0401. From swimming to swarming: Escherichia coli cell motility in two-dimensions. Swiecicki JM, Sliusarenko O, Weibel DB. Integr Biol (Camb). 2013 Dec;5(12):1490-4. doi: 10.1039/c3ib40130h. Structure-activity studies of divin: an inhibitor of bacterial cell division. Zhou M, Eun YJ, Guzei IA, Weibel DB. ACS Med Chem Lett. 2013 Sep 12;4(9):880-885. Bacteria-surface interactions. Tuson HH, Weibel DB. Soft Matter. 2013 May 14;9(18):4368-4380. Bacterial growth and adaptation in microdroplet chemostats. Jakiela S, Kaminski TS, Cybulski O, Weibel DB, Garstecki P. Angew Chem Int Ed Engl. 2013 Aug 19;52(34):8908-11. doi: 10.1002/anie.201301524. Epub 2013 Jul 5. No abstract available. Divin: a small molecule inhibitor of bacterial divisome assembly. Eun YJ, Zhou M, Kiekebusch D, Schlimpert S, Trivedi RR, Bakshi S, Zhong Z, Wahlig TA, Thanbichler M, Weibel DB. J Am Chem Soc. 2013 Jul 3;135(26):9768-76. doi: 10.1021/ja404640f. Epub 2013 Jun 18. Draft Genome Sequences of Two Pairs of Human Intestinal Bifidobacterium longum subsp. longum Strains, 44B and 1-6B and 35B and 2-2B, Consecutively Isolated from Two Children after a 5-Year Time Period. Shkoporov AN, Efimov BA, Khokhlova EV, Chaplin AV, Kafarskaya LI, Durkin AS, McCorrison J, Torralba M, Gillis M, Sutton G, Weibel DB, Nelson KE, Smeianov VV. Genome Announc. 2013 May 16;1(3). pii: e00234-13. doi: 10.1128/genomeA.00234-13. Inhibitors of bacterial tubulin target bacterial membranes in vivo. Foss MH, Eun YJ, Grove CI, Pauw DA, Sorto NA, Rensvold JW, Pagliarini DJ, Shaw JT, Weibel DB. Medchemcomm. 2013 Jan 1;4(1):112-119. Epub 2012 Jul 18. Flagellum density regulates Proteus mirabilis swarmer cell motility in viscous environments. Tuson HH, Copeland MF, Carey S, Sacotte R, Weibel DB. J Bacteriol. 2013 Jan;195(2):368-77. doi: 10.1128/JB.01537-12. Epub 2012 Nov 9. MinD and MinE interact with anionic phospholipids and regulate division plane formation in Escherichia coli. Renner LD, Weibel DB. J Biol Chem. 2012 Nov 9;287(46):38835-44. doi: 10.1074/jbc.M112.407817. Epub 2012 Sep 25. Rapid identification of ESKAPE bacterial strains using an autonomous microfluidic device. Ho JY, Cira NJ, Crooks JA, Baeza J, Weibel DB. PLoS One. 2012;7(7):e41245. doi: 10.1371/journal.pone.0041245. Epub 2012 Jul 27.

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