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个人简介

谭蔚泓,美国密西根大学物理化学博士,中国科学院物理化学硕士,湖南师范大学化学本科。2000年国家杰出青年基金B获得者、2010年国家重大科学研究计划(蛋白质组)首席科学家,2012年国家自然基金会创新群体负责人,2013年“111”创智引新基地负责人。2005年创立湖南大学生物医学工程中心,2010至2015年担任湖南大学生物学院创院院长。现任教育部科技委员会委员,国家自然科学基金委化学部咨询委员会委员等。现任美国化学会JACS《Journal of American Chemical Society》杂志副主编.曾任美国《Analytical Chemistry》杂志副主编,现任ACS Nano、Chemical Science、中国科学化学,国家科学评论等国内外杂志编委。 谭蔚泓教授长期从事生命分析化学和化学生物学研究和教学工作,解决了分析化学与生物医学交叉领域中的一些关键科学问题,在国际生物分析化学领域有着重要的影响,入选2014、2015、2016年汤森路透全球高被引研究人员名单。在Science、PNAS和Nature系列等国际知名学术刊物上发表学术论文500余篇,H-index 102,SCI他引35,000多次。研究成果获2014年国家自然科学二等奖。2005年当选美国AAAS Fellow,2015年当选中国科学院院士,2016年当选发展中国家科学院院士。

研究领域

长期从事生命分析化学和化学生物学研究和教学工作

近期论文

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Phosphorylated Lipid-Conjugated Oligonucleotide Selectively Anchors on Cell Membranes with High Alkaline Phosphatase Expression Jin C , He JX , Zou JM , Xuan WJ, Fu T , Wang RW, Tan WH Nature Communications, ,[2019]>> Fulltext Link A cell membrane-anchored DNA nano-platform for programming cellular interactions Jin LiKanyu XunKe PeiXiaojing LiuXueyu PengYulin DuLiping Qiu and Weihong Tan Journal of the American Chemical Society, ,[2019]>> Fulltext Link Hypoxia-activated PEGylated aptamer/antibody for cancer imaging with improved specificity Fang Zhou, Ting Fu, Qin Huang, Hailan Kuai, Liuting Mo, Honglin Liu, Qianqian Wang, Yongbo Peng, Dongmei Han, Zilong Zhao, Xiaohong Fang, Weihong Tan Journal of the American Chemical Society, ,[2019]>> Nitric Oxide-Activated “Dual-Key–One-Lock” Nanoprobe for in Vivo Molecular Imaging and High-Specificity Cancer Therapy Lili Teng, Guosheng Song, Yongchao Liu, Xiaoyu Han, Zhe Li, Youjuan Wang, Shuangyan Huan, Xiao-Bing Zhang, Weihong Tan Journal of the American Chemical Society, ,[2019]>> Generalized Preparation of Two-Dimensional Quasi-nanosheets via Self-assembly of Nanoparticles Ca R, Yang T, Lin KT, Lyu YF, Zhu BW, Zhen He Z, Zhang LL, Kitamura Y, Qiu LP, Chen XG, Zhao YL, Chen Z and Tan WH Journal of the American Chemical Society, 1725?1734 DOI:10.1021/jacs.8b12415,[2019]>> Engineering of Bioinspired, Size-controllable and Self-degradable Cancertargeting DNA Nanoflowers via Incorporation of an Artificial Sandwich Base Zhang LL, Abdullah R, Hu XX, Bai HR, Fan HH, He L, Liang H, Zou JM, Liu YL, Sun Y, Zhang XB, and Tan WH Journal of the American Chemical Society, DOI: 10.1021/jacs.8b10795,[2019]>> Engineering Aptamer with Enhanced Affinity by Triple Helix-based Terminal Fixation Lianhui ZhaoXiaoyan QiXiaochen YanYunfei HuangXingguo LiangLiqin ZhangSai WangWeihong Tan Journal of the American Chemical Society, ,[2019]>> Fulltext Link Engineering Aptamer with Enhanced Affinity by Triple Helix-based Terminal Fixation Aptamer Displacement Reaction from Live-Cell Surfaces and Its Applications Long LiXigao ChenCheng CuiXiaoshu PanXiaowei LiHoda Safari YazdQiong WuLiping QiuJuan Li*Weihong Tan Journal of the American Chemical Society, ,[2019]>> Fulltext Link Aptamer Displacement Reaction from Live-Cell Surfaces and Its Applications Construction of a Multiple-Aptamer-Based DNA Logic Device on Live Cell Membranes via Associative Toehold Activation for Accurate Cancer Cell Identification Xu Chang, Chao Zhang, Cheng Lv, Yang Sun,Mingzhi Zhang, Yumeng Zhao, Linlin Yang, Da Han, Weihong Tan* Journal of the American Chemical Society, ,[2019]>> Elucidation and Structural Modeling of CD71 as a Molecular Target for Cell-Specific Aptamer Binding Xiaoqiu Wu, Honglin Liu, Dongmei Han, Bo Peng, Hui Zhang, Lin Zhang, Jiang, lin Li, Jing Liu, Cheng CuiSenbiao FangMin LiMao Ye Weihong Tan Journal of the American Chemical Society, ,[2019]>> Ostwald ripening-mediated grafting of metal-organic frameworks on a single colloidal nanocrystal to form uniform and controllable MXF, Yuan Liu, Yu Yang, Yujia Sun, Jibin Song, Nicholas G. Rudawski, Xiaoyuan Chen, Weihong Tan Journal of the American Chemical Society, ,[2019]>> Artificial signal feedback network mimicking cellular adaptivity Hui Liu, Qiuxia Yang, Ruizi Peng, Hailan Kuai, Yifan Lyu, Xiaoshu Pan, Qiaoling Liu*, Weihong Tan Journal of the American Chemical Society, ,[2019]>> Fulltext Link Artificial signal feedback network mimicking cellular adaptivity Molecular engineering-based aptamer-drug conjugates with accurate tunability of drug ratios for drug combination targeted cancer therapy Fang Zhou#, Peng Wang#, Yongbo Peng, Pengge Zhang, Qin Huang, Weidi Sun, Nongyue He, Ting Fu, Zilong Zhao*, Xiaohong Fang*, and Weihong Tan Angewandte Chemie International Edition, ,[2019]>> In situ amplification-based imaging of RNA in living cells Zhihe Qing,* Jingyuan Xu, Jinlei Hu, Jing Zheng, Lei He, Zhen Zou, Sheng Yang, Weihong Tan, and Ronghua Yang Angewandte Chemie International Edition, ,[2019]>> Fulltext Link NIR‐II Driven Plasmon‐Enhanced Catalysis for a Timely Supply of Oxygen to Overcome Hypoxia‐Induced Radiotherapy Tolerance Yue Yang, Mei Chen, Bingzhe Wang, Peng Wang, Yongchun Liu, Yan Zhao, Kun Li, Guosheng Song Xiao‐Bing Zhang Weihong Tan Angewandte Chemie International Edition, ,[2019]>> Naked‐Eye Readout of Analyte‐Induced NIR Fluorescence Responses by an Initiation‐Input‐Transduction Nanoplatform Dailiang Zhang, Linlin Wang, Xi Yuan, Yijun Gong, Hongwen Liu, Jing Zhang, Xiaobing Zhang, Yanlan Liu, and Weihong Tan Angewandte Chemie International Edition, ,[2019]>> Regulation of Protein Activity and Cellular Functions Mediated by Molecularly Evolved Nucleic Acids Tan J, Zhao MM, Wang J, Li AH, Liang L, Zhang LQ, Yuan Q, and Tan WH Angewandte Chemie International Edition, 1621-1625 DOI:10.1002/anie.201809010,[2019]>> Fulltext Link Spherical directed Synthesis and enhanced cellular internalization of metal-crosslinked DNA micelles Lyn YF, Guo Y, Cai R, Peng RZ, Hong CY, Chen XG, Hou WJ, Li XW, Tan J, Zou YX, Zhang XB, Liu QL, and Tan WH Angewandte Chemie International Edition, 10.1016/j.chempr.2019.02004,[2019]>> Interaction-Transferable Graphene-Isolated Superstable AuCo Nanocrystal-Enabled Direct Cyanide Capture Lufeng Zhang, Jiashi Zhang, Zhongfan Zheng, Yixin Liao, Yiting Xu, Zhiwei Li, Shengkai Li, Liang Zhang, Zhangkun Liu, Haibo Yi, Zhuo Chen,*, and Weihong Tan Analytical Chemistry, ,[2019]>> Fulltext Link

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