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S. Yang, M. Wang, D. Tian, X. Zhang, K. Cui, S. Lü, H.-H. Wang, M. Long, Z. Nie*. DNA-functionalized artificial mechanoreceptor for de novo force-responsive signaling. Nat. Chem. Biol., 2024, DOI: 10.1038/s41589-024-01572-x.
W. Kang, F. Xiao, X. Zhu, X. Ling, S. Xie, R. Li, P. Yu, L. Cao, C. Lei*, Y. Qiu, T. Liu, Z. Nie*. Engineering anti-CRISPR proteins to create CRISPR-Cas protein switches for activatable genome editing and viral protease detection. Angew. Chem. Int. Ed., 2024, 63, e20240599.
F. He, M. Wang, J. Wang, H-.H. Wang, Z. Nie*. An extracellular miRNA-responsive artificial receptor via dynamic DNA nano-assembly for biomarker-driven therapy. Angew. Chem. Int. Ed., 2023, 62, e202305227.
R. Tang, Y. Fu, B. Gong, Y.-Y. Fang, H.-H. Wang, Y. Huang, Z. Nie*. P. Wei*. A chimeric conjugate of antibody and programmable DNA nanoassembly smartly activates T cells for precise cancer cell targeting. Angew. Chem. Int. Ed., 2022, 61, e202205902.
M. Wang, D. Yang, Q Lu, L. Liu, Z. Cai, Y. Wang, H.-H. Wang, P. Wang*, Z. Nie*. Spatially reprogramed receptor organization to switch cell behavior using a DNA origami-templated aptamer nanoarray. Nano Lett., 2022, 22, 8445-8454.
J. Zhang, H. Li, B. Lin, X. Luo, P. Yin, T. Yi, B. Xue, X.-L. Zhang, H. Zhu, Z. Nie*. Development of near-infrared nucleic acid mimics of fluorescent proteins for in vivo imaging of viral RNA with turn-on fluorescence. J. Am. Chem. Soc., 2021, 143, 19317-19329.
K. Shi, S. Xie, R. Tian, S. Wang, Q. Lu, D. Gao, C. Lei, H. Zhu, Z. Nie*. A CRISPR-Cas autocatalysis-driven feedback amplification network for supersensitive DNA diagnostics. Science Advances, 2021, 7, eabc7802.
H. Li, J. Gao, L. Cao, X. Xie, J. Fan, H. Wang, H.-H. Wang*, Z. Nie*. A DNA molecular robot that autonomously walks on the cell membrane to drive cell motility. Angew. Chem. Int. Ed., 2021, 60, 26087-26095.
J. Zhang, Z. Qiu, J. Fan, F. He, W. Kang, S. Yang, H.-H. Wang*, J. Huang*, Z. Nie*. Scan and Unlock: A programmable DNA molecular automaton for cell-selective activation ligand-based signaling. Angew. Chem. Int. Ed., 2021, 60, 6733-6743.
X. Zhu, R. Tang, S Wang, X. Chen, J. Hu, C. Lei, Y. Huang, H. Wang, Z. Nie*, S. Yao. Protein@inorganic nanodumpling system for high-loading protein delivery with activatable fluorescence and magnetic resonance bimodal imaging capabilities, ACS Nano, 2020, 14, 2172-2182.
X. Luo, B. Xue, G. Feng, J. Zhang, B. Lin, P. Zeng, H. Li, H. Yi, X.-L. Zhang, H. Zhu*, Z. Nie*.Lighting up the native viral RNA genome with a fluorogenic probe for the live-cell visualization of virus infection. J. Am. Chem. Soc., 2019, 141, 5182-5191.
G. Feng, X. Luo, X. Lu, S. Xie, L. Deng, W. Kang, F. He, J. Zhang, C. Lei*, B, Lin, Y. Huang, Z. Nie*, S. Yao. Engineering of nucleic acids and synthetic cofactors as holo sensors for probing signaling molecules in the cellular membrane microenvironment.Angew. Chem. Int. Ed., 2019, 58, 6590-6594. (Very Important Paper, Back Cover)
M. Wang, F. He, H. Li, S.H. Yang, J. Zhang, P. Ghosh, H.-H. Wang*, Z. Nie*. Near-infrared light-activated DNA-agonist nanodevice for nongenetically and remotely controlled cellular signaling and behaviors in live animals. Nano Lett., 2019, 19, 2603-2613.
H. Li, M. Wang, T. Shi, S. Yang, J. Zhang, H.-H. Wang*, Z. Nie*. A DNA-mediated chemically induced dimerization (D-CID) nanodevice for nongenetic engineering of receptor to control cell behavior. Angew. Chem. Int. Ed., 2018, 57,10226-10230. (Hot paper)
Y. Li, S. Sun, L. Fan, S. Hu, Y. Huang, K. Zhang, Z. Nie*, S. Yao. Peptide logic circuits based on chemoenzymatic ligation for programmable cell apoptosis.Angew. Chem. Int. Ed., 2017, 56, 14888-14892.
Z. Nie*, P. Wang, C. Tian, C. Mao*. Synchronization of two assembly processes to build responsive DNA nanostructures. Angew. Chem. Int. Ed., 2014, 53, 8402-8405.
C. Lei, Y. Huang, Z. Nie*, J. Hu, L. Li, G. Lu, Y. Han, S. Yao. Supercharged fluorescent protein as a versatile probe for homogenous DNA detection and methylation analysis. Angew. Chem. Int. Ed., 2014, 53, 8358-8362.
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