个人简介
分析化学家 1935年11月21日生于上海,籍贯湖南长沙。1959年毕业于苏联列宁格勒大学化学系。湖南大学教授,曾任该校校长。1991年当选为中国科学院学部委员(院士)
研究领域
主要研究方向为化学计量学及化学生物传感器。研制成功多种新型电化学及光化学传感器,并实现产业化生产。合成多种新的分析及增敏试剂与离子载体,建立铌等稀有金属分析方法
近期论文
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Wu H.W., Liu S.H., Jiang J.H., Shen G.L., Yu R.Q. A sensitive electrochemical biosensor for detection of DNA methyltransferase activity by combining DNA methylation-sensitive cleavage and terminal transferase-mediated extension. Chemical Communications, 2012, 48, 6280-6282.
Zhao J.J., Zhang L.L., Jiang J.H., Shen G.L., Yu R.Q. A label-free fluorescence DNA probe based on ligation reaction with quadruplex formation for highly sensitive and selective detection of nicotinamide adenine dinucleotide. Chemical Communications, 2012, 48, 4468-4470.
Jin J.W., Chen Z.P., Li L.M., Steponavicius R., Thennadil S.N., Yang J., Yu R.Q. Quantitative Spectroscopic Analysis of Heterogeneous Mixtures: the Correction of Multiplicative Effects Caused by Variations in Physical Properties of Samples. Analytical Chemistry, 2012, 84, 320-326.
Zhang Z., Tang A., Liao S., Chen P., Wu Z., Shen G.L, Yu R.Q. Oligonucleotide probes applied for sensitive enzyme-amplified electrochemical assay of mercury(II) ions. Biosensors and Bioelectronics, 2011, 26, 3320-3324.
Qiu L.P., Wu Z.S., Shen G.L., Yu R.Q. Highly sensitive and selective bifunctional oligonucleotide probe for homogeneous parallel fluorescence detection of protein and nucleotide sequence. Analytical Chemistry, 2011, 83, 3050-3057.
He J.L., Yang Y.F., Shen G.L., Yu R.Q. Electrochemical aptameric sensor based on the Klenow fragment polymerase reaction for cocaine detection. Biosensors and Bioelectronics, 2011, 26, 4222-4226.
Feng K., Qiu L.P., Yang Y., Wu Z.S., Shen G.L., Yu R.Q. Label-free optical bifunctional oligonucleotide probe for homogeneous amplification detection of disease markers. Biosensors and Bioelectronics, 2011, 29, 66-75.
Zhang Z., Zhou J., Tang A., Wu Z., Shen G., Yu R.Q. Scanning electrochemical microscopy assay of DNA based on hairpin probe and enzymatic amplification biosensor. Biosensors and Bioelectronics, 2010, 25, 1953-1957.
Sun C., Zhang L.L., Jiang J., Shen G.L., Yu R.Q. Electrochemical DNA biosensor based on proximity-dependent DNA ligation assays with DNAzyme amplification of hairpin substrate signal. Biosensors and Bioelectronics, 2010, 25, 2483-2489.
He J.L., Wu Z.S., Zhou H., Wang H.Q., Jiang J.H., Shen G.L., Yu R.Q. Fluorescence aptameric sensor for strand displacement amplification detection of cocaine. Analytical Chemistry, 2010, 82, 1358-1364.
Kong R.M., Zhang X.B., Zhang L.L., Jin X.Y., Huan S.Y., Shen G.L., Yu R.Q. An ultrasensitive electrochemical “turn-on” label-free biosensor for Hg2+ with AuNP-functionalized reporter DNA as a signal amplifier. Chemical Communications, 2009, 5633-5635.
Chen H., Zheng Y., Jiang J.H., Wu H.L., Shen G.L., Yu R.Q. An ultrasensitive chemiluminescence biosensor for cholera toxin based on ganglioside-functionalized supported lipid membrane and liposome,Biosensors and Bioelectronics,2008, 24, 684-689.
Chen J.W., Liu X.P., Feng K.J., Liang Y., Jiang J.H., Shen G.L., Yu R.Q. Detection of adenosine using surface-enhanced Raman scattering based on structure-switching signaling aptamer, Biosensors and Bioelectronics, 2008, 24, 66-71.
Lin W.Q., Jiang J.H., Zhou Y.P., Wu H.L., Shen G.L., Yu R.Q. Support vector machine based training of multilayer feedforward neural networks as optimized by particle swarm algorithm: Application in QSAR studies of bioactivity of organic compounds. Journal of Computational Chemistry, 2007, 28, 519-527.
Lin W.Q., Jiang J.H., Yang H.F., Ozaki Y., Shen G.L., Yu R.Q. Characterization of chloramphenicol palmitate drug polymorphs by raman mapping with multivariate image segmentation using a spatial directed agglomeration clustering method. Analytical Chemistry, 2006, 78, 6003-6011.