个人简介
Harvard College, A.B. 1983
Universität Erlangen-Nürnberg 1983-1984
University of California, Berkeley, Ph.D. 1990
Yale University, NIH Postdoctoral Fellow 1990-1994
研究领域
DNA structure and topology in multi-protein DNA complexes and DNA loops.
Construction of nanoscale objects using DNA and protein-DNA complexes.
DNA packaging by peptides used for transfection of DNA and siRNA.
Role of DNA structure in transcription and gene regulation.
近期论文
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Title: Direct observation of dynamic mechanical regulation of DNA condensation by environmental stimuli.
Author(s): Lee A; Karcz A; Akman R; et al.
DOI: 10.1002/anie.201403499 / Author-provided URL :
added
18-Dec-14
Title: DNA, flexibly flexible.
Author(s): Kahn JD
DOI: 10.1016/j.bpj.2014.06.007 / Author-provided URL :
added
18-Dec-14
Title: Enhanced silencing and stabilization of siRNA polyplexes by histidine-mediated hydrogen bonds.
Author(s): Chou ST; Hom K; Zhang D; et al.
DOI: 10.1016/j.biomaterials.2013.10.019 / Author-provided URL :
added
18-Dec-14
Title: Tethered particle motion reveals that LacI·DNA loops coexist with a competitor-resistant but apparently unlooped conformation.
Author(s): Revalee JD; Blab GA; Wilson HD; et al.
DOI: 10.1016/j.bpj.2013.12.024 / Author-provided URL :
added
18-Dec-14
Title: LacI-DNA-IPTG Loops: Equilibria among Conformations by Single-Molecule FRET
Author(s): Goodson, Kathy A.; Wang, Zifan; Haeusler, Aaron R.; et al.
Source: Journal of Physical Chemistry B Volume: 117 Issue: 16 Pages: 4713-4722 Published: APR 25 2013
DOI: 10.1021/jp308930c
added
25-Jun-13
Title: Rationally Designed Coiled-Coil DNA Looping Peptides Control DNA Topology
Author(s): Gowetski, Daniel B.; Kodis, Erin J.; Kahn, Jason D.
Source: Biophysical Journal Volume: 104 Issue: 2 Pages: 420A Published: JAN 29 2013
added
25-Jun-13
Title: Rationally designed coiled-coil DNA looping peptides control DNA topology.
Author(s): Gowetski DB; Kodis EJ; Kahn JD
DOI: 10.1093/nar/gkt553 / Author-provided URL :
added
18-Dec-14
Title: Surface-Modified HK:siRNA Nanoplexes with Enhanced Pharmacokinetics and Tumor Growth Inhibition
Author(s): Chou, Szu-Ting; Leng, Qixin; Scaria, Puthupparampil; et al.
Source: Biomacromolecules Volume: 14 Issue: 3 Pages: 752-760 Published: MAR 2013
DOI: 10.1021/bm3018356
added
25-Jun-13
Title: FRET studies of a landscape of Lac repressor-mediated DNA loops
Author(s): Haeusler, Aaron R.; Goodson, Kathy A.; Lillian, Todd D.; et al.
Source: Nucleic Acids Research Volume: 40 Issue: 10 Pages: 4432-4445 Published: MAY 2012
DOI: 10.1093/nar/gks019
added
28-Jun-12
Title: FRET and Sm-FRET Characterization of a Lac Repressor-Dna Looping Landscape
Author(s): Kahn, Jason D.; Haeusler, Aaron R.; Goodson, Kathy A.; et al.
Source: Biophysical Journal Volume: 100 Issue: 3 Pages: 70-71 Published: 2011