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Renewable and Ultralong Nanoelectrochemical Sensor: Nanoskiving Fabrication and Application for Monitoring Cell Release
Analytical Chemistry ( IF 6.7 ) Pub Date : 2015-12-22 00:00:00 , DOI: 10.1021/acs.analchem.5b04055
Wanling Qiu 1 , Muzhen Xu 1 , Ruixin Li 1 , Xiaomeng Liu 1 , Meining Zhang 1
Affiliation  

Nanoscaled electrode has been attracting increasing attention because of striking fundamentals and practical applications. Usually, the nanoscaled electrode is fabricated by manual or photo or electron-beam lithography, which is not easy to reproducibly fabricate with simple equipment. In this paper, a cost-effective method, nanoskiving, is developed to fabricate an ultralong nanowire electrode (ULNE). The ULNE is reproducibly obtained by simply sectioning a sandwich epoxy block with a Au film. The width of ULNE could be down to nanometer dependence on the thickness of the Au film, while the length could reach to the millimeter. Thus, the created Au ULNE shows steady-state microamperometric current, characteristic of the nanoelectrode array attributed to its macroscopic length and nanoscaled width without considering the overlap of the diffusion layer of the neighboring nanoelectrode. The electrodeposited Pt/Au ULNE displays unusual electrocatalytic performance toward both the oxidation and reduction of hydrogen peroxide and, as a nanosensor, gives rise to high sensitivity and selectivity of monitoring hydrogen peroxide released from cells stimulated by ascorbic acid.

中文翻译:

可再生和超长纳米电化学传感器:纳米刮片的制作及其在监测细胞释放中的应用

由于惊人的基本原理和实际应用,纳米级电极已引起越来越多的关注。通常,纳米级电极是通过手动或光电子照相平版印刷术制造的,这不容易用简单的设备重复生产。在本文中,开发了一种成本有效的方法,即纳米刮削,以制造超长纳米线电极(ULNE)。通过简单地将夹心环氧块与Au膜切片,可重复获得ULNE。ULNE的宽度可以取决于金膜的厚度而降低到纳米,而长度可以达到毫米。因此,创建的Au ULNE显示出稳态的微安培电流,纳米电极阵列的特征在于其宏观长度和纳米级宽度,而没有考虑相邻纳米电极的扩散层的重叠。电沉积的Pt / Au ULNE对过氧化氢的氧化和还原均显示出不同寻常的电催化性能,作为纳米传感器,它对监测由抗坏血酸刺激的细胞释放的过氧化氢具有很高的灵敏度和选择性。
更新日期:2015-12-22
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