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Iodine-Catalyzed Cascade Formal [3 + 3] Cycloaddition Reaction of Indolyl Alcohol Derivatives with Enaminones: Constructions of Functionalized Spirodihydrocarbolines
ACS Catalysis ( IF 11.3 ) Pub Date : 2013-10-08 00:00:00 , DOI: 10.1021/cs400703u
Wen-Juan Hao 1 , Shun-Yi Wang 1 , Shun-Jun Ji 1
Affiliation  

A simple and practical method for the synthesis of spirodihydrocarboline derivatives from indolyl alcohol derivatives with enaminones via an iodine-catalyzed cascade formal [3 + 3] cycloaddition reaction has been developed. The reaction afforded the desired products under mild conditions in moderate to good yields with excellent regioselectivities.

中文翻译:

碘催化吲哚醇衍生物与烯胺酮的级联式[3 + 3]环加成反应:功能化螺二烃基化合物的构建

开发了一种简单实用的方法,该方法通过碘催化的级联[3 + 3]环加成反应,从吲哚醇衍生物与烯胺酮合成螺二烃代衍生物。该反应在温和条件下以中等至良好的产率提供了所需的产物,具有优异的区域选择性。
更新日期:2013-10-08
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