Stem cell dynamics, migration and plasticity during wound healing.,Nature Cell Biology

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Stem cell dynamics, migration and plasticity during wound healing.
Nature Cell Biology ( IF 17.3 ) Pub Date : 2019-01-02 , DOI: 10.1038/s41556-018-0237-6
Sophie Dekoninck ₁ , Cédric Blanpain _{1,

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Affiliation

Tissue repair is critical for animal survival. The skin epidermis is particularly exposed to injuries, which necessitates rapid repair. The coordinated action of distinct epidermal stem cells recruited from various skin regions together with other cell types, including fibroblasts and immune cells, is required to ensure efficient and harmonious wound healing. A complex crosstalk ensures the activation, migration and plasticity of these cells during tissue repair.

中文翻译：

伤口愈合过程中的干细胞动力学、迁移和可塑性。

组织修复对于动物的生存至关重要。皮肤表皮特别容易受到伤害，因此需要快速修复。从不同皮肤区域招募的不同表皮干细胞与其他细胞类型（包括成纤维细胞和免疫细胞）的协调作用是确保伤口高效、和谐愈合所必需的。复杂的串扰确保了这些细胞在组织修复过程中的激活、迁移和可塑性。

更新日期：2019-01-25

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