Schistosomiasis japonica caused by Schistosoma japonicum infection is recognized as a considerable economic and public health concern in Asia. Oncomelania hupensis is the sole intermediate host of S. japonicum. The only molluscicide recommended by World Health Organization (WHO) since 1960s is relative toxic to other aquatic species. In this article, we evaluated the novel molluscicide PPU07 in field trials on their efficiency against O. hupensis and toxicity for local fish. 25% PPU07 sulfate WP exhibited similar molluscicidal effect at 2.0 g/m² and 2.0 g/m³ in the spraying and immersion trials with the WHO recommended molluscicide niclosamide (1 g/m² and 1 g/m³). The mortality rates reached 95% and 96%, respectively. Moreover, little toxicity was observed for local fish and other aquatic organisms at the effective mollusicicidal concentrations. In all, 25% PPU07 sulfate WP is a promising molluscicide for snail control, particularly in semi-commercial or commercial aquaculture ponds.

在日本，由日本血吸虫感染引起的日本血吸虫病被认为是对经济和公共卫生的重大关注。钉螺是日本血吸虫的唯一中间宿主。自1960年代以来，世界卫生组织（WHO）推荐的唯一杀软体动物剂对其他水生物种具有相对毒性。在这篇文章中，我们评估了他们对效率的田间试验新型灭螺PPU07 O.钉螺和毒性本地鱼类。25％PPU07硫酸盐可湿性粉剂在世界卫生组织推荐的杀软体动物烟酰胺（1 g / m ^2）的喷雾和浸没试验中，在2.0 g / m ²和2.0 g / m ³时表现出相似的杀软体动物作用。和1 g / m ³）。死亡率分别达到95％和96％。此外，在有效的杀软体动物浓度下，对本地鱼类和其他水生生物几乎没有观察到毒性。总之，25％的PPU07硫酸盐可湿性粉剂是一种有希望的蜗牛防治螺杀剂，特别是在半商业或商业水产养殖池塘中。