Vitamin D Protects Against Alcohol‐Induced Liver Cell Injury Within an NRF2–ALDH2 Feedback Loop,Molecular Nutrition & Food Research

当前位置： X-MOL 学术 › Mol. Nutr. Food Res. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Vitamin D Protects Against Alcohol‐Induced Liver Cell Injury Within an NRF2–ALDH2 Feedback Loop
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2019-02-06 , DOI: 10.1002/mnfr.201801014
Hong Zhang ₁ , Lian Xue ₁ , Bingyan Li ₂ , Zengli Zhang ₁ , Shasha Tao _{1,

3}

Affiliation

Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide. Oxidative stress induced during the alcohol metabolism plays a crucial role in ALD, and clinical evidence demonstrates the prevalence and risks of vitamin D (VD) deficiency in ALD. This study aims to explore the mechanism of VD administration to ameliorate alcohol‐induced cell injury.

中文翻译：

维生素D可防止NRF2-ALDH2反馈回路内的酒精引起的肝细胞损伤

酒精性肝病（ALD）是全球发病率和死亡率的主要原因。酒精代谢过程中引起的氧化应激在ALD中起着至关重要的作用，临床证据表明ALD中维生素D（VD）缺乏症的患病率和风险。这项研究旨在探讨VD给药改善酒精诱导的细胞损伤的机制。

更新日期：2019-02-06

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南